Orazamide

Product Name: Orazamide
CAS No.: 2574-78-9
Chemical Name: Orazamide
Synonyms: Orazamide;Qrazamide;AICA orotate;aicamindihydrate;aicoratdihydrate;Orazamide orotate;orazamidedihydrate;Orazamide USP/EP/BP;aicaorotatedihydrate;5-Aminoimedazole-4-carboxamideorotate
CBNumber: CB1476435
Molecular Formula: C9H10N6O5
Formula Weight: 282.21
MOL File: 2574-78-9.mol

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Orazamide Property

Melting point:: 284-285 °C (decomp)
InChI: InChI=1S/C5H4N2O4.C4H6N4O.2H2O/c8-3-1-2(4(9)10)6-5(11)7-3;5-3-2(4(6)9)7-1-8-3;;/h1H,(H,9,10)(H2,6,7,8,11);1H,5H2,(H2,6,9)(H,7,8);2*1H2
InChIKey: RAZMBRTXTADRMQ-UHFFFAOYSA-N
SMILES: C1(C(=O)O)NC(NC(=O)C=1)=O.C1(C(=O)N)NC=NC=1N.O.O
CAS DataBase Reference: 2574-78-9(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: O670608
Product name: Orazamide
Packaging: 500mg
Price: $60
Updated: 2021/12/16

TRC

Product number: O670608
Product name: Orazamide
Packaging: 2.5g
Price: $175
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003691
Product name: ORAZAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $504.79
Updated: 2021/12/16

AvaChem

Product number: 1613
Product name: Orazamide
Packaging: 10mg
Price: $189
Updated: 2021/12/16

AHH

Product number: MT-57521
Product name: Orazamide
Purity: 98%
Packaging: 0.1g
Price: $330
Updated: 2021/12/16

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Orazamide Chemical Properties,Usage,Production

Originator

Aicamine, Labaz , France ,1971

Uses

Orazamide is an AICA orotate. Orazamide can prevent anti-TB drug-induced liver damage by downregulating the protein expression of HMGB 1 and RAGE in liver tissue and inhibiting the secretion of inflammatory factors. Orazamide can be used in research on hepatitis and liver cirrhosis[1].

Manufacturing Process

14.4 grams of 4-amino-5-imidazolecarboxamide (monohydrate) and 17.4 grams of orotic acid (monohydrate) were dissolved with heating in 600 cc of water. The solution is decolorized with Norit, cooled and then filtered off. 28.8 grams of a white crystalline salt (dihydrate) is obtained with MP 284°C (decomposition).

Therapeutic Function

Hepatoprotectant

References

[1] HE L, et al. Study on the Prevention Mechanism of Anti-tuberculosis Drug-induced Liver Injury with Orazamide Based on HMGB1-RAGE Signaling Pathway[J]. China Pharmacy, 2021: 2229-2235.

Orazamide Preparation Products And Raw materials

Raw materials

Orotic acid Imidazole OROTIC ACID MONOHYDRATE

Preparation Products

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Orazamide Suppliers

China 63 Europe 2 Germany 1 South Korea 1 United Kingdom 4 United States 12 Global 83

Hunan Zhongnan Pharmaceutical Co., Ltd.

Tel: 0739-5278828,0739-5270119,0739-5270025
Fax: 0739-5271610/0739-5270365
Country: China
ProdList: 3
Advantage: 60

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Shijiazhuang Als Pharmaceutical Technology Co., Ltd.

Tel: 0311-85150550 18932901920
Fax: 0311-85150550
Email: alspharm@163.com
Country: China
ProdList: 231
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

SIMAGCHEM CORP

Tel: +86-5922680277 +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17346
Advantage: 58

Xiamen AmoyChem Co., Ltd

Tel: +86-86-5926051114 +8615060885618
Email: sales@amoychem.com
Country: China
ProdList: 6369
Advantage: 58

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View Lastest Price from Orazamide manufacturers

Dideu Industries Group Limited

Product: Orazamide 2574-78-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-30

2574-78-9, OrazamideRelated Search:

L-Alanyl-L-Glutamine Prochloraz Formamide Transglutaminase N,N-Dimethylformamide Boc-D-Glutamine Potassium orotate Orotic acid Benzamide Chlorantraniliprole Orazamide OROTIC ACID MONOHYDRATE Whey 2-[(4-AMINO-PHENYL)-ETHYL-AMINO]-ETHANOL CARBOXYLIC ACID Ca Orotate Orazamide Tetrahydro

aicamindihydrate

aicaorotatedihydrate

aicoratdihydrate

imidazole-4-carboxamide,5-amino-,compd.withoroticacid(1:1),dihydrate

1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid compound with 5-amino-1h-imidazole-4-carboxamide (1:1)

4-amino-5-imidazolecarboxamideorotatedihydrate

5-Aminoimedazole-4-carboxamideorotate

5-aminoimidazole-4-carboxamideorotatedihydrate

orazamidedihydrate

oroticacidcompd.with5(or4)-aminoimidazole-4(or5)-carboxamide(1:1)dihy

1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid, compound with 5-amino-1H-imidazole-4-carboxamide (1:1)

AICA orotate

5-AMINOIMIDAZOLE-4-CARBOXAMIDEOROTATE(ORAZAMIDE)

5-Aminoimidazole-4-carboxamide orotate

Orazamide

(3S)-3-(4-methoxyphenyl)-2-methyl-3H-1,2-benzothiazole 1,1-dioxide

Qrazamide

Orazamide USP/EP/BP

Orazamide/5-Aminoimidazole-4-carboxamide orotate

Orazamide orotate

2574-78-9

C5H3N2O4C4H6N4O

C5H4N2O4C5H7N3O2H2O

C5H4N2O4C4H6N4O

API