ChemicalBook > CAS DataBase List > CINALUKAST
CINALUKAST
- Product Name
- CINALUKAST
- CAS No.
- 128312-51-6
- Chemical Name
- CINALUKAST
- Synonyms
- Ro 24-591;RO 24-5913;CINALUKAST;C·Nalukast;2,2-Diethyl-N-[3-[(E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]succinamidic acid;(E)-4-[[3-(2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL)PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID;4-[[3-[(1E)-2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL]PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID;Butanoic acid, 4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]aMino]-2,2-diethyl-4-oxo-;Ro 24-5913, (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
- CBNumber
- CB1486281
- Molecular Formula
- C23H28N2O3S
- Formula Weight
- 412.55
- MOL File
- 128312-51-6.mol
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CINALUKAST Property
- storage temp.
- 2-8°C
- solubility
- DMSO: >10 mg/mL
- form
- Powder
- color
- off-white
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Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C6239
- Product name
- Cinalukast
- Purity
- ~98% (HPLC)
- Packaging
- 5mg
- Price
- $203
- Updated
- 2024/03/01
TRC
- Product number
- C441900
- Product name
- Cinalukast
- Packaging
- 5mg
- Price
- $130
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC20441
- Product name
- Cinalukast
- Packaging
- 2mg
- Price
- $125
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FC20441
- Product name
- Cinalukast
- Packaging
- 5mg
- Price
- $227.2
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6930
- Product name
- Cinalukast
- Packaging
- 10mg
- Price
- $282
- Updated
- 2021/12/16
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CINALUKAST Chemical Properties,Usage,Production
Uses
A novel leukotriene D4 antagonist.
Definition
ChEBI: 2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in th human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.
Biological Activity
Potent, selective CysLT 1 (LTD 4 ) leukotriene receptor antagonist (IC 50 = 6.4 nM). Inhibits LTD 4 -induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol.
CINALUKAST Preparation Products And Raw materials
Raw materials
Preparation Products
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CINALUKAST Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91