Pentoxyverine

Product Name: Pentoxyverine
CAS No.: 77-23-6
Chemical Name: Pentoxyverine
Synonyms: PENTOXIFYLLINE;Urex;Carbetapentane;Tuclase;Pentoxyverine Base;ucb2543;Atussil;Sedotussin;u.c.b.2543;U.C.B. 2543
CBNumber: CB1497317
Molecular Formula: C20H31NO3
Formula Weight: 333.46
MOL File: 77-23-6.mol

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Pentoxyverine Property

Boiling point:: 165-170 °C (1.33Pa)
Density: 1.048±0.06 g/cm3(Predicted)
refractive index: 1.4990-1.5010
storage temp.: Refrigerator
solubility: Dichloromethane (Slightly), Methanol (Slightly)
pka: 9.69±0.25(Predicted)
form: Oil
color: Clear Very Dark Red to Brown
CAS DataBase Reference: 77-23-6(CAS DataBase Reference)
NIST Chemistry Reference: 1-Cyclopentanecarboxylate, 2-(diethylaminoethoxy)ethyl-1-phenyl-(77-23-6)

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Safety

Hazardous Substances Data: 77-23-6(Hazardous Substances Data)
Toxicity: LD50 oral in rat: 150mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C178025
Product name: Carbetapentane
Packaging: 50mg
Price: $135
Updated: 2021/12/16

TRC

Product number: C178025
Product name: Carbetapentane
Packaging: 100mg
Price: $215
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007262
Product name: PENTOXYVERINE
Purity: 95.00%
Packaging: 1MG
Price: $401.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007262
Product name: PENTOXYVERINE
Purity: 95.00%
Packaging: 5G
Price: $2150
Updated: 2021/12/16

AHH

Product number: API-1156
Product name: Carbetapentane
Purity: 98%
Packaging: 10g
Price: $710
Updated: 2021/12/16

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Pentoxyverine Chemical Properties,Usage,Production

Originator

Asthma ,Nichiiko

Uses

Carbetapentane is an antitussive anticonvulsant sigma site agonist.

Definition

ChEBI: 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester is a member of benzenes.

Manufacturing Process

1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.
1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.
1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.
A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.

brand name

Toclase (Pfizer).

Therapeutic Function

Antitussive

Pentoxyverine Preparation Products And Raw materials

Raw materials

α-Phenylcyclopentanecarbonyl chloride 1-Phenylcyclopentanecarboxylic acid phenylacetonitrile Sesamol Calcium chloride Trichloroethylene Diethylamine 1,4-Dibromobutane 1-Phenyl-1-cyclopentanecarbonitrile

Preparation Products

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Pentoxyverine Suppliers

China 94 Europe 2 Germany 2 Switzerland 1 United Kingdom 6 United States 17 Global 122

LGM Pharma

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Ivy Fine Chemicals

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View Lastest Price from Pentoxyverine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Pentoxyverine Citrite 77-23-6
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 1000KG
Release date: 2021-11-23

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

Product: Pentoxyverine 77-23-6
Price: US $0.00/KG
Min. Order: 100g
Purity: 98%+
Supply Ability: 100kg
Release date: 2020-09-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pentoxyverine 77-23-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

77-23-6, PentoxyverineRelated Search:

Ethylbenzene Methylcyclopentane CARBETAPENTANE CITRATE,CARBETAPENTANE CITRATE SALT,PENTOXYVERINE CITRATE RESMETHRIN Bromocyclopentane Ethyl acrylate Ethylparaben Cyclopentyl chloride Ethyl formate Ethyl acetate 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester Ethyl propionate acetic acid, triethoxy-, ethyl ester Ethanol Cyclopentane PIPERAZINE CITRATE HYDRATE Clomiphene Citrate Ranitidinebismuthcitrate

1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester

1-phenyl-1-cyclopentanecarboxylate

1-Phenylcyclopentane-1-Carboxylic acid diethylaminoethoxyethyl ester

1-phenylcyclopentane-1-carboxylicaciddiethylaminoethoxyethylester

1-phenyl-cyclopentanecarboxylicaci2-(2-(diethylamino)ethoxy)ethylester

1-phenylcyclopentanecarboxylicacid2-(2-diethylaminoethoxy)ethylester

ucb2543

Urex

Pentoxyverine Base

CARETAPENTANE

Carbetapentane (base and/or unspecified salts)

PENTOXIFYLLINE

2-(2-DIETHYLAMINOETHOXY)ETHYL 1-PHENYLCYCLOPENTANECARBOXYLATE CITRATE

2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane

1-Phenylcyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl

1-phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethyloxy)ethyl ester

2-(2-diethylaminoethyloxy)ethyl 1-phenylcyclopentane-1-carboxylate

2-(2-Diethylaminoethoxy)ethyl 1-phenylcyclopentane-1-carboxylate

Carbetapentane

PENTOSYVERINECITRATE

Pentoxyverine citrate (Carbetapentane)

2-(2-Diethylaminoethoxy)ethyl 1-phenylcyclopentanecarboxylate

2-(2-diethylaminoethoxy)ethyl1-phenylcyclopentanecarboxylate

2-(Diethylaminoethoxy)ethyl 1-phenyl-1-cyclopentanecarboxylate

2-(Diethylaminoethoxy)ethyl 1-phenylcyclopentyl-1-carboxylate

2-(diethylaminoethoxy)ethyl1-phenyl-1-cyclopentanecarboxylate

2-(diethylaminoethoxy)ethyl1-phenylcyclopentyl-1-carboxylate

2-[2-(Diemthylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylate

Atussil

Cyclopentanecarboxylic acid, 1-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester

Ethanol, 2-[2-(diethylamino)ethoxy]-, 1-phenylcyclopentanecarboxylate (ester)

Pentoxiverin

Pentoxiverine

Pentoxyverin

Pentoxyverine

Sedotussin

Tuclase

U.C.B. 2543

u.c.b.2543

Pentoxyverine USP/EP/BP

Pentoxyverine Citrite

Cough will clear

Pentoxyverine Monomer

77-23-6

C26H39NO10

Miscellaneous Biochemicals