PHENAMIL METHANESULFONATE
- Product Name
- PHENAMIL METHANESULFONATE
- CAS No.
- 1161-94-0
- Chemical Name
- PHENAMIL METHANESULFONATE
- Synonyms
- MHPIZTURFVSLTJ-UHFFFAOYSA-N;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-, methanesulfonate (1:1)
- CBNumber
- CB1502107
- Molecular Formula
- C13H16ClN7O4S
- Formula Weight
- 401.8
- MOL File
- 1161-94-0.mol
PHENAMIL METHANESULFONATE Property
- storage temp.
- 2-8°C
- solubility
- 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble2.5mg/mL
- form
- solid
- color
- yellow
- CAS DataBase Reference
- 1161-94-0
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- P203
- Product name
- Phenamil methanesulfonate salt
- Purity
- solid
- Packaging
- 5mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- P203
- Product name
- Phenamil methanesulfonate salt
- Purity
- solid
- Packaging
- 25mg
- Price
- $177.6
- Updated
- 2024/03/01
- Product number
- 14308
- Product name
- Phenamil (methanesulfonate)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 14308
- Product name
- Phenamil (methanesulfonate)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 14308
- Product name
- Phenamil (methanesulfonate)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $357
- Updated
- 2024/03/01
PHENAMIL METHANESULFONATE Chemical Properties,Usage,Production
Chemical Properties
off-white to yellow solid
Uses
Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte
Uses
Phenamil methanesulfonate salt has been used:
- to stimulate adipocyte differentiation in 3T3 cells
- to test its effect on lateral flagella expression in Vibrio shilonii
- in nanoparticle preparation to test its effect on osteo/odontoblastic differentiation
General Description
Phenamil, a derivative of amiloride is an inhibitor of sodium channels including acid sensing ion channel (ASIC) and epithelial sodium channels (ENaC).
Biochem/physiol Actions
Phenamil is an inducer of peroxisome proliferator-activated receptor γ (PPARγ) and inhibits diamine oxidase. By favoring tribbles homolog 3 (Trb3) expression, phenamil holds therapeutic potential to treat pulmonary artery hypertension (PAH) and idiopathic PAH. It is also a bone morphogenetic protein (BMP) activator, which favors osteogenesis and odontogenesis of stem cells.
storage
Store at +4°C
PHENAMIL METHANESULFONATE Preparation Products And Raw materials
Raw materials
Preparation Products
PHENAMIL METHANESULFONATE Suppliers
View Lastest Price from PHENAMIL METHANESULFONATE manufacturers
- Product
- PHENAMIL METHANESULFONATE 1161-94-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 10 tons
- Release date
- 2024-09-03