6-CHLORO-2-PYRAZINECARBOXAMIDE
- Product Name
- 6-CHLORO-2-PYRAZINECARBOXAMIDE
- CAS No.
- 36070-79-8
- Chemical Name
- 6-CHLORO-2-PYRAZINECARBOXAMIDE
- Synonyms
- 6-Chloropyrazinecarboxamide;6-Chloropyrazine-2-carboxamide;2-Chloro-6-pyrazinecarboxamide;6-CHLORO-2-PYRAZINECARBOXAMIDE;PyrazinecarboxaMide, 6-chloro-;2-Pyrazinecarboxamide, 6-chloro-;6-Chloropyrazine-2-carboxylic acid amide;6-chloro-2-pyrazinecarboxamide(SALTDATA: FREE)
- CBNumber
- CB51110693
- Molecular Formula
- C5H4ClN3O
- Formula Weight
- 157.56
- MOL File
- 36070-79-8.mol
6-CHLORO-2-PYRAZINECARBOXAMIDE Property
- Melting point:
- 180-182℃
- Density
- 1.478±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CBR02075
- Product name
- 6-Chloro-2-pyrazinecarboxamide
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 1 g
- Price
- $259
- Updated
- 2025/07/31
- Product number
- C384468
- Product name
- 6-Chloropyrazine-2-carboxamide
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- C384468
- Product name
- 6-Chloropyrazine-2-carboxamide
- Packaging
- 250mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 4538AB
- Product name
- 6-Chloropyrazine-2-carboxamide
- Packaging
- 250mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 143891
- Product name
- 6-Chloropyrazine-2-carboxamide
- Purity
- 95%
- Packaging
- 1g
- Price
- $452
- Updated
- 2021/12/16
6-CHLORO-2-PYRAZINECARBOXAMIDE Chemical Properties,Usage,Production
Synthesis
23688-89-3
36070-79-8
Intermediate 13-2: Synthesis of 6-chloropyrazine-2-carboxamide 6-Chloropyrazine-2-carboxylic acid (2.00 g, 12.62 mmol) was dissolved in DMF (7 mL) and the solution was cooled to -40 °C. Under stirring, N-methylpyrrolidone (NMP, 2.77 mL, 25.23 mmol) and isobutyl chloroformate (3.27 mL, 25.23 mmol) were added sequentially. After controlling the reaction temperature to slowly rise to -20 °C over 20 min, ammonia (NH4OH) was added. A precipitate rapidly formed in the reaction mixture and after continued stirring for 15 min, the precipitate was collected by filtration and washed with cold water. Purification by recrystallization from ethanol (EtOH) afforded the title compound 6-chloropyrazine-2-carboxamide (670 mg, 34% yield) as light brown needle-like crystals. The product was characterized by 1H NMR (500 MHz, DMSO-d6): δ 7.93 (br s, 1H), 8.24 (br s, 1H), 8.99 (s, 1H), 9.12 (s, 1H).
References
[1] Patent: WO2009/81195, 2009, A1. Location in patent: Page/Page column 77
[2] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 2, p. 450 - 453
6-CHLORO-2-PYRAZINECARBOXAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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