5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE

Product Name: 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
CAS No.: 1214-79-5
Chemical Name: 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
Synonyms: Dimethylamiloride;DMA HYDROCHLORIDE;5-dimethylamiloride;5-(N,N-Dimethyl)-amiloride;5-(N,N-DIMETHYL)AMILORIDE HCL;5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE;AMILORIDE, 5-(N,N-DIMETHYL)-, HYDROCHLORIDE;5-(N,N-Dimethyl)amiloride hydrochloride;3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide;3-Amino-N-carbamimidoyl-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide
CBNumber: CB6697022
Molecular Formula: C8H12ClN7O
Formula Weight: 257.68
MOL File: 1214-79-5.mol

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5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Property

Melting point:: 216-217 °C
Density: 1.68±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: Yellow solid.
pka: 8.66±0.46(Predicted)
color: Light yellow to yellow
InChI: 1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H
InChIKey: IIUPTHVVXMBJMQ-UHFFFAOYSA-N
SMILES: Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)\N=C(\N)N

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: 2811
WGK Germany: -
HazardClass: 6.1(b)
PackingGroup: III
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A4562
Product name: 5-(N,N-Dimethyl)amiloride hydrochloride
Packaging: 25mg
Price: $233.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: A4562
Product name: 5-(N,N-Dimethyl)amiloride hydrochloride
Packaging: 100mg
Price: $812
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: API0008812
Product name: 5-(N,N-DIMETHYL)AMILORIDE HYDROCHLORIDE
Purity: 95.00%
Packaging: 100MG
Price: $1109.06
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008812
Product name: 5-(N,N-DIMETHYL)AMILORIDE HYDROCHLORIDE
Purity: 95.00%
Packaging: 25MG
Price: $713.71
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008812
Product name: 5-(N,N-DIMETHYL)AMILORIDE HYDROCHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $179.3
Updated: 2021/12/16

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5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na²/H⁺ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Biochem/physiol Actions

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Suppliers

China 34 Germany 1 Switzerland 2 United Kingdom 1 United States 6 Global 44

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1214-79-5, 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDERelated Search:

Pyrazinamide 2-amino-3-chloro-5-methyl-pyrazine 2-Chloropyrazine 2-Amino-5-chloropyrazine 2-Chloro-6-methylpyrazine 5-METHYL-PYRAZIN-2-YLAMINE AMILORIDE Amiloride hydrochloride 5-AMINOPYRAZINE-2-CARBOXAMIDE 2-AMINO-3-CHLOROPYRAZINE 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Pyrazinecarboxaldehyde, 5-(dimethylamino)- (9CI) (PYRAZIN-2-YL)METHANAMINEHYDROCHLORIDE 3-AMINO-6-CHLOROPYRAZINE-2-CARBALDEHYDE 2-AMINOMETHYLPYRAZINE DIHYDROCHLORIDE Pyrazinecarboxamide, 3-amino- (7CI,9CI) 2-AMINO-3-AMINOMETHYLPYRAZINE 6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE

5-(N,N-DIMETHYL)AMILORIDE HCL

5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE

AMILORIDE, 5-(N,N-DIMETHYL)-, HYDROCHLORIDE

3-AMINO-N-(AMINOIMINOMETHYL)-5-(DIMETHYLAMINO)-6-CHLORO-PYRAZINE-CARBOXAMIDE HYDROCHLORIDE

3-amino-n-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride

DMA, 3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride

3-Amino-5-(dimethylamino)-6-chloro-N-(diaminomethylene)pyrazinecarboxamide

5-(N,N-Dimethyl)-amiloride

3-Amino-5-(N,N-dimethylamino)-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide

6-Chloro-3-amino-5-(dimethylamino)-N-(diaminomethylene)-2-pyrazinecarboxamide

Dimethylamiloride

N-(Diaminomethylene)-3-amino-5-(dimethylamino)-6-chloropyrazine-2-carboxamide

3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide

3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide

3-azanyl-N-[bis(azanyl)methylidene]-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide

DMA HYDROCHLORIDE

5-dimethylamiloride

2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-

3-Amino-N-carbamimidoyl-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide

5-(<i>N</i>,<i>N</i>-Dimethyl)amiloride hydrochloride

1214-79-5

C8H12ClN7OHCl

Monovalent Ion Channels

Ion Channels

Sodium Channel Modulators

Voltage-gated Ion Channels

Amiloride and Derivatives

BioChemical

Cell Signaling and Neuroscience

Cell Biology