ChemicalBook > CAS DataBase List > 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE

5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE

Product Name
5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
CAS No.
1214-79-5
Chemical Name
5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
Synonyms
Dimethylamiloride;DMA HYDROCHLORIDE;5-dimethylamiloride;5-(N,N-Dimethyl)-amiloride;5-(N,N-DIMETHYL)AMILORIDE HCL;5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE;AMILORIDE, 5-(N,N-DIMETHYL)-, HYDROCHLORIDE;3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide;3-Amino-5-(dimethylamino)-6-chloro-N-(diaminomethylene)pyrazinecarboxamide;6-Chloro-3-amino-5-(dimethylamino)-N-(diaminomethylene)-2-pyrazinecarboxamide
CBNumber
CB6697022
Molecular Formula
C8H12ClN7O
Formula Weight
257.68
MOL File
1214-79-5.mol
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5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Property

Melting point:
216-217 °C
Density 
1.68±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Yellow solid.
pka
8.66±0.46(Predicted)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
2811
WGK Germany 
-
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A4562
Product name
5-(N,N-Dimethyl)amiloride hydrochloride
Packaging
25mg
Price
$239
Updated
2024/03/01
Sigma-Aldrich
Product number
A4562
Product name
5-(N,N-Dimethyl)amiloride hydrochloride
Packaging
100mg
Price
$790
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0008812
Product name
5-(N,N-DIMETHYL)AMILORIDE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$179.3
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008812
Product name
5-(N,N-DIMETHYL)AMILORIDE HYDROCHLORIDE
Purity
95.00%
Packaging
25MG
Price
$713.71
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008812
Product name
5-(N,N-DIMETHYL)AMILORIDE HYDROCHLORIDE
Purity
95.00%
Packaging
100MG
Price
$1109.06
Updated
2021/12/16
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5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Biochem/physiol Actions

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Suppliers

China 16 Germany 1 Switzerland 2 United Kingdom 1 United States 4 Global 24

1214-79-5, 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDERelated Search:

Pyrazinamide 2-amino-3-chloro-5-methyl-pyrazine 2-Chloropyrazine 2-Amino-5-chloropyrazine 2-Chloro-6-methylpyrazine 5-METHYL-PYRAZIN-2-YLAMINE AMILORIDE Amiloride hydrochloride 5-AMINOPYRAZINE-2-CARBOXAMIDE 2-AMINO-3-CHLOROPYRAZINE 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE Pyrazinecarboxaldehyde, 5-(dimethylamino)- (9CI) (PYRAZIN-2-YL)METHANAMINEHYDROCHLORIDE 3-AMINO-6-CHLOROPYRAZINE-2-CARBALDEHYDE 2-AMINOMETHYLPYRAZINE DIHYDROCHLORIDE Pyrazinecarboxamide, 3-amino- (7CI,9CI) 2-AMINO-3-AMINOMETHYLPYRAZINE 6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE

  • 5-(N,N-DIMETHYL)AMILORIDE HCL
  • 5-(N,N-DIMETHYL)-AMILORIDE HYDROCHLORIDE
  • AMILORIDE, 5-(N,N-DIMETHYL)-, HYDROCHLORIDE
  • 3-AMINO-N-(AMINOIMINOMETHYL)-5-(DIMETHYLAMINO)-6-CHLORO-PYRAZINE-CARBOXAMIDE HYDROCHLORIDE
  • 3-amino-n-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride
  • DMA, 3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride
  • 3-Amino-5-(dimethylamino)-6-chloro-N-(diaminomethylene)pyrazinecarboxamide
  • 5-(N,N-Dimethyl)-amiloride
  • 3-Amino-5-(N,N-dimethylamino)-6-chloro-N-(aminoiminomethyl)-2-pyrazinecarboxamide
  • 6-Chloro-3-amino-5-(dimethylamino)-N-(diaminomethylene)-2-pyrazinecarboxamide
  • Dimethylamiloride
  • N-(Diaminomethylene)-3-amino-5-(dimethylamino)-6-chloropyrazine-2-carboxamide
  • 3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazinamide
  • 3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide
  • 3-azanyl-N-[bis(azanyl)methylidene]-6-chloro-5-(dimethylamino)pyrazine-2-carboxamide
  • DMA HYDROCHLORIDE
  • 5-dimethylamiloride
  • 2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-
  • 1214-79-5
  • C8H12ClN7OHCl
  • Monovalent Ion Channels
  • Ion Channels
  • Sodium Channel Modulators
  • Voltage-gated Ion Channels
  • Amiloride and Derivatives
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology