2-Chloro-6-methylpyrazine

Product Name: 2-Chloro-6-methylpyrazine
CAS No.: 38557-71-0
Chemical Name: 2-Chloro-6-methylpyrazine
Synonyms: 6-Methyl-2-chloropyrazine;2-Methyl-6-chloropyrazine;2-CHLORO-6-METHYLPYRAZINE;2-Chloro-6-methylpyrazine97%;Pyrazine, 2-chloro-6-methyl-;2-Chloro-6-methylpyrazine >2-Chloro-6-methyl-1,4-diazine;2-Chloro-6-methylpyrazine 97%;2-Chloro-6-methylpyrazine, >=98%;2-Chloro-6-methylpyrazine ISO 9001：2015 REACH
CBNumber: CB5283341
Molecular Formula: C5H5ClN2
Formula Weight: 128.56
MOL File: 38557-71-0.mol

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2-Chloro-6-methylpyrazine Property

Melting point:: 49-52
Boiling point:: 83°C/35mmHg(lit.)
Density: 1.234±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: -0.89±0.10(Predicted)
color: White to Almost white
InChIKey: CKUVSPQGYLELRG-UHFFFAOYSA-N

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 22-26-36/37/39
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS013631
Product name: 2-Chloro-6-methylpyrazine
Purity: Aldrich
Packaging: 1g
Price: $216
Updated: 2025/07/31

TCI Chemical

Product number: C2777
Product name: 2-Chloro-6-methylpyrazine
Purity: >98.0%(GC)
Packaging: 1g
Price: $108
Updated: 2025/07/31

TCI Chemical

Product number: C2777
Product name: 2-Chloro-6-methylpyrazine
Purity: >98.0%(GC)
Packaging: 5g
Price: $430
Updated: 2025/07/31

TRC

Product number: C368855
Product name: 2-Chloro-6-methylpyrazine
Packaging: 1g
Price: $120
Updated: 2021/12/16

Apolloscientific

Product number: OR9783
Product name: 2-Chloro-6-methylpyrazine
Purity: 97%
Packaging: 25g
Price: $155
Updated: 2021/12/16

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2-Chloro-6-methylpyrazine Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

2-Chloro-6-methylpyrazine was used in the synthesis of palm site inhibitors of HCV NS5B polymerase and potent dipeptidyl peptidase IV inhibitors.

Synthesis

930798-25-7

38557-71-0

Step 3: To a 5L sealed reaction tube was added (6-chloropyrazin-2-yl)acetic acid (220 g, 1.27 mol, 1.00 equiv) and deionized water (3L). The reaction mixture was stirred at 130 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently extracted with ether (2 x 3 L). The organic phases were combined, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to afford 238 g (73% yield) of 2-chloro-6-methylpyrazine as a yellow solid.

References

[1] Patent: US2015/31674, 2015, A1. Location in patent: Paragraph 0325; 0322

2-Chloro-6-methylpyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-6-methylpyrazine Suppliers

Americas 1 Belgium 1 China 167 Czech Republic 1 Europe 2 Germany 2 India 3 Japan 1 Switzerland 1 United Kingdom 6 United States 20 Global 205

Yangzhou beierdun new material technology co., ltd

Tel: 13776432722
Email: 358854490@qq.com
Country: China
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
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Energy Chemical

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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
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Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
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Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
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View Lastest Price from 2-Chloro-6-methylpyrazine manufacturers

PNP Biotech Co. Ltd

Product: 2-Chloro-6-methylpyrazine 38557-71-0
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-17

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Chloro-6-methylpyrazine 38557-71-0
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

Career Henan Chemical Co

Product: 2-Chloro-6-methylpyrazine 38557-71-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

38557-71-0, 2-Chloro-6-methylpyrazineRelated Search:

Tetramethylpyrazine N-(5-CHLORO-3-PYRAZINE)-4-AMINOBENZENESULFONAININO Sulfachoropyrazine sodium 2-Methylpyrazine Glipizide Hydrochlorothiazide Pyrazinamide Epichlorohydrin METHYL 3-AMINO-5,6-DICHLORO-2-PYRAZINECARBOXYLATE 5-(N,N-HEXAMETHYLENE)-AMILORIDE 5,6-DICHLORO-2,3-DICYANOPYRAZINE 3-CHLORO-2,5-DIMETHYLPYRAZINE Amiloride hydrochloride Difluorochloromethane Chloroacetic acid 2-amino-3-chloro-5-methyl-pyrazine 2-CHLORO-3-METHYLPYRAZINE 6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE

2-Chloro-6-methylpyrazine 97%

2-Methyl-6-chloropyrazine

6-Methyl-2-chloropyrazine

2-Chloro-6-methylpyrazine, >=98%

2-Chloro-6-methylpyrazine97%

2-CHLORO-6-METHYLPYRAZINE

2-Chloro-6-methyl-1,4-diazine

2-Chloro-6-methylpyrazine &gt

Pyrazine, 2-chloro-6-methyl-

2-Chloro-6-methylpyrazine ISO 9001：2015 REACH

6-chloro-2-methyl-2,5-dihydropyrazine-2,5-diide

38557-71-0

Halides

Pyrazines, Pyrimidines & Pyridazines