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Pyrazinecarboxamide, 3-amino- (7CI,9CI)

Product Name
Pyrazinecarboxamide, 3-amino- (7CI,9CI)
CAS No.
32587-10-3
Chemical Name
Pyrazinecarboxamide, 3-amino- (7CI,9CI)
Synonyms
Aminopyrazine carboxamide;Pyrazinecarboxamide, 3-amino;3-amino-2-pyrazinecarboxamide;2-Pyrazinecarboxamide, 3-amino-;Pyrazinecarboxamide, 3-amino- (7CI,9CI);3-Amino-pyrazine-2-carboxylic acid amide
CBNumber
CB21051869
Molecular Formula
C5H6N4O
Formula Weight
138.13
MOL File
32587-10-3.mol
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Pyrazinecarboxamide, 3-amino- (7CI,9CI) Property

Melting point:
239.3 °C
Boiling point:
375.8±37.0 °C(Predicted)
Density 
1.426±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
form 
Solid
pka
13.68±0.50(Predicted)
Appearance
Light brown to brown Solid
CAS DataBase Reference
32587-10-3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
A615668
Product name
3-Aminopyrazine-2-carboxamide
Packaging
500mg
Price
$175
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA139395
Product name
3-Aminopyrazine-2-carboxamide
Packaging
1g
Price
$81
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA139395
Product name
3-Aminopyrazine-2-carboxamide
Packaging
2g
Price
$141
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0076955
Product name
3-AMINO-PYRAZINE-2-CARBOXYLIC ACID AMIDE
Purity
95.00%
Packaging
1G
Price
$262.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA139395
Product name
3-Aminopyrazine-2-carboxamide
Packaging
5G
Price
$282
Updated
2021/12/16
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Pyrazinecarboxamide, 3-amino- (7CI,9CI) Chemical Properties,Usage,Production

Synthesis Reference(s)

Journal of the American Chemical Society, 81, p. 2472, 1959 DOI: 10.1021/ja01519a047

Synthesis

16298-03-6

32587-10-3

Example 2 Synthesis of 3-aminopyrazine-2-carboxamide (Intermediate 1): methyl 3-aminopyrazine-2-carboxylate (5.0 g, 33 mmol) was dissolved in concentrated ammonium hydroxide solution (30 mL), heated to 60°C and kept for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and the precipitated solid was collected by filtration. The solid was washed well with water and ether in turn to afford the title compound 3-aminopyrazine-2-carboxamide as a brown solid (3.7 g, 82% yield). The product was characterized by 1H NMR (500 MHz, DMSO-d6): δ 8.19 (d, J = 2.4 Hz, 1H), 8.07 (br s, 2H), 7.80 (d, J = 2.4 Hz, 1H), 7.59 (br s, 2H). Mass spectrum (ES+): m/z 139 ([M + H]+).

References

[1] Journal of Heterocyclic Chemistry, 2012, vol. 49, # 4, p. 865 - 872
[2] Patent: CN106699759, 2017, A. Location in patent: Paragraph 0050; 0051; 0052
[3] Patent: US2007/259876, 2007, A1. Location in patent: Page/Page column 17
[4] Journal of the American Chemical Society, 1945, vol. 67, p. 1711
[5] Patent: US2011/118269, 2011, A1. Location in patent: Page/Page column 13

Pyrazinecarboxamide, 3-amino- (7CI,9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrazinecarboxamide, 3-amino- (7CI,9CI) Suppliers

Alfa Aesar
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400-6106006
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021-67582001/03/05
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saleschina@alfa-asia.com
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China
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30123
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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Jinan Trio PharmaTech Co., Ltd.
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0531-88811783
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+86 (531) 55696010 QQ 1762738062
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China
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SuZhou ShiYa Biopharmaceuticals, Inc.
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Shanghai Witofly Chemical Co.,Ltd
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China
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Shanghai XinKai Chemical Technology Co., Ltd.
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Shanghai Tombiopharma Chemical Co. Ltd.
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China
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Shanghai Boyners Pharm-Tech Co., Ltd.
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13817873692
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021-31329586
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Nanjing Huang Tai Pharmaceutical Technology Co. Ltd.
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China
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View Lastest Price from Pyrazinecarboxamide, 3-amino- (7CI,9CI) manufacturers

Career Henan Chemical Co
Product
Pyrazinecarboxamide, 3-amino- (7CI,9CI) 32587-10-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2019-08-29

32587-10-3, Pyrazinecarboxamide, 3-amino- (7CI,9CI)Related Search:


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  • Pyrazinecarboxamide, 3-amino
  • 3-amino-2-pyrazinecarboxamide
  • 32587-10-3
  • AMIDE