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ALOIN

Product Name
ALOIN
CAS No.
8015-61-0
Chemical Name
ALOIN
Synonyms
alloin;Aloins;Cafaloin;Jafaloin;Socaloin;Ai3-19097;Ugandaloin;Aloin, cape;ALOIN, CRUDE;ALOIN,POWDER
CBNumber
CB1502400
Molecular Formula
C21H22O9
Formula Weight
418.39398
MOL File
8015-61-0.mol
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ALOIN Property

storage temp. 
2-8°C
solubility 
pyridine: 50 mg/mL, clear, dark red
form 
Solid
color 
Dark Yellow
Stability:
Hygroscopic
InChIKey
AFHJQYHRLPMKHU-GQMFJIQQNA-N
SMILES
C1(O)=C2C([C@H]([C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C3=C(C2=O)C(O)=CC=C3)=CC(CO)=C1 |&1:4,5,6,8,10,12,r|
EPA Substance Registry System
Aloin (8015-61-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
8
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A575423
Product name
Aloin(mixtureofAandB)
Packaging
1g
Price
$65
Updated
2021/12/16
TRC
Product number
A575423
Product name
Aloin(mixtureofAandB)
Packaging
5g
Price
$265
Updated
2021/12/16
ChemScene
Product number
CS-0032167
Product name
Aloin(mixtureofA&B)
Purity
98.03%
Packaging
1mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0032167
Product name
Aloin(mixtureofA&B)
Purity
98.03%
Packaging
10mg
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001864
Product name
ALLOIN
Purity
95.00%
Packaging
5MG
Price
$505.52
Updated
2021/12/16
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ALOIN Chemical Properties,Usage,Production

Description

Aloin is the major anthraquinone glycoside obtained from the Aloe species[1]. It exhibits anti-inflammatory and anti-oxidative activities[2]. As a quality standard compound based on the Chinese Pharmacopoeia (CHP), it has a wide range of pharmacological activities, including anti-tumor, anti-inflammatory, anti-osteoporotic, organ-protective, anti-viral, anti-microbial, anti-parasitic, and laxative potentials[3]. Moreover, it regulates blood lipids and glucose and improves neuropathic pain effects, depicting the potential to be transformed into promising medicines and healthcare products.

Uses

Aloin is used as a stimulant-laxative, treating constipation by inducing bowel movements. The compound is present in what is commonly referred to as the aloe latex that exudes from cells adjacent to the vascular bundles, found under the rind of the leaf and in between it and the gel.

Purification Methods

Aloin forms the monohydrate as lemon yellow crystals on crystallisation from H2O (450g/1.5L) which has a lower m ~70-80o than the anhydrous substance. [Cahn & Simonsen J Chem Soc 2573 1932, Hay & Haynes J Chem Soc 3141 1956.]

References

[1] Lee L, et al. Inhibitory effects of aloin on TGFBIp-mediated septic responses. Journal of Asian Natural Products Research, 2020; 23: 189-203.
[2] Lee L, et al.Suppressive effects of aloin on polyphosphate-mediated vascular inflammatory responses. Journal of Asian Natural Products Research, 2020; 23: 89-99.
[3] Yang Y, et al.Can aloin develop to medicines or healthcare products?. Biomedicine Pharmacotherapy, 2022; 153: 113421.

ALOIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ALOIN Suppliers

BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5115
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
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View Lastest Price from ALOIN manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
ALOIN 8015-61-0
Price
US $80.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-23
Career Henan Chemical Co
Product
ALOIN 8015-61-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-17

8015-61-0, ALOINRelated Search:


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