4-DEOXYPYRIDOXINE 5-PHOSPHATE
- Product Name
- 4-DEOXYPYRIDOXINE 5-PHOSPHATE
- CAS No.
- 883-84-1
- Chemical Name
- 4-DEOXYPYRIDOXINE 5-PHOSPHATE
- Synonyms
- 4-Deoxypyridoxine Phosphate;4-DEOXYPYRIDOXINE 5-PHOSPHATE;4-Deoxypyridoxine 5'-phosphate;(5-hydroxy-4,6-dimethyl-3-pyridyl)methyl dihydrogen phosphate;(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate;(5-hydroxy-4,6-dimethyl-pyridin-3-yl)methyl dihydrogen phosphate;3-Pyridinemethanol, 5-hydroxy-4,6-dimethyl-, 3-(dihydrogen phosphate)
- CBNumber
- CB1506291
- Molecular Formula
- C8H12NO5P
- Formula Weight
- 233.16
- MOL File
- 883-84-1.mol
4-DEOXYPYRIDOXINE 5-PHOSPHATE Property
- storage temp.
- Store at -20°C
- solubility
- Water: soluble
- form
- A crystalline solid
- color
- White to off-white
- Water Solubility
- Water: soluble
N-Bromosuccinimide Price
- Product number
- 29973
- Product name
- 4-Deoxypyridoxine Phosphate
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 29973
- Product name
- 4-Deoxypyridoxine Phosphate
- Packaging
- 25mg
- Price
- $456
- Updated
- 2024/03/01
- Product number
- 29973
- Product name
- 4-Deoxypyridoxine Phosphate
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 29973
- Product name
- 4-Deoxypyridoxine Phosphate
- Packaging
- 10mg
- Price
- $214
- Updated
- 2024/03/01
- Product number
- CS-0022825
- Product name
- 4-Deoxypyridoxine5'-phosphate
- Purity
- ≥98.0%
- Packaging
- 5mg
- Price
- $120
- Updated
- 2021/12/16
4-DEOXYPYRIDOXINE 5-PHOSPHATE Chemical Properties,Usage,Production
Uses
4-Deoxypyridoxine 5'-phosphate is a Pyridoxal 5'-phosphate analogue and a sphingosine 1-phosphate (S1P) inhibitor. 4-Deoxypyridoxine 5'-phosphate inhibits ornithine decarboxylase activity with a Ki of 60 μM. 4-Deoxypyridoxine 5'-phosphate is a competitive inhibitor of the activation of glutamate apodecarboxylase by Pyridoxal 5'-phosphate (Ki of 0.27 μM) and strongly inhibits glutamate-dependent labeling of glutamate decarboxylase[1][2][3].
References
[1] Mamoru Ohtoyo, et al. Scintillation Proximity Assay to Detect the Changes in Cellular Dihydrosphingosine 1-Phosphate Levels. Lipids. 2016 Oct;51(10):1207-1216. DOI:10.1007/s11745-016-4187-0
[2] M J Connor, et al. Epidermal Pyridoxal 5'-phosphate Depletion, Inhibition of DNA Synthesis, and Inhibition of the Expression of Ornithine Decarboxylase Activity by the Vitamin B-6 Antagonist 4'-deoxypyridoxine. J Invest Dermatol. 1983 Aug;81(2):136-9. DOI:10.1111/1523-1747.ep12543346
[3] D L Martin, et al. Glutamate-dependent Active-Site Labeling of Brain Glutamate Decarboxylase. J Neurochem. 1990 Aug;55(2):524-32. DOI:10.1111/j.1471-4159.1990.tb04166.x
4-DEOXYPYRIDOXINE 5-PHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
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