PEA15 antibody
Source Reactivity Background References- Product Name
- PEA15 antibody
- Chemical Name
- PEA15 antibody
- Synonyms
- PEA15 antibody
- CBNumber
- CB15671372
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb6687
- Product name
- PEA15 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb6687
- Product name
- PEA15 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
PEA15 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
PEA-15 is a 15 kDa phosphoprotein expressed abundantly in astrocytes and fibroblasts as well as in tissues, including the lung and eye. The protein has been shown to coordinate cell growth, death, and glucose utilization. The amino-terminal DED domain of PEA-15 mediates its binding to FADD or Erk and further regulates the Erk and apoptosis signaling pathways. PEA-15 can be phosphorylated at two serine residues, Ser104 and Ser116, located within the carboxy terminus. Phosphorylation at these sites regulates binding to Erk and FADD.
References
[1] Danziger, N. et al. (1995) J. Neurochem. 64, 1016-1025.
[2] Krueger, J. et al. (2005) Mol. Biol. Cell 16, 3552-3561.
[3] Renganathan, H. et al. (2005) Biochem. J. 390, 729-735.
[4] Condorelli, G. et al. (1998) EMBO J. 17, 3858-3866.
PEA15 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
PEA15 antibody Suppliers
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