TXN2 antibody
Applications Immunogen Background- Product Name
- TXN2 antibody
- Chemical Name
- TXN2 antibody
- Synonyms
- TXN2 antibody;Rabbit Polyclonal TXN2 Antibody
- CBNumber
- CB65703122
- Formula Weight
- 0
- MOL File
- Mol file
TXN2 antibody Chemical Properties,Usage,Production
Applications
The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity.
Immunogen
Anti-human TXN2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TXN2 protein 60-166 amino acids purified from E. coli.
Background
Thioredoxin-2 is a low molecular weight redox protein. TRX2 contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The TXN2 is involved in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Upon stimulation of Fas, TXN2 mediates denitrosylation of mitochondria-associated caspase-3, a process required for caspase-3 activation, and promoted apoptosis.
TRX2 is important at low oxidative stress conditions.
MTRX is involved in the regulation of the mitochondrial membrane potential and cell death. Mitochondrial thioredoxin plays an important roles in protection against oxidant-induced apoptosis. Thioredoxin1 and thioredoxin2 have opposed regulatory functions on hypoxia-inducible factor-1alpha.
TXN2 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
TXN2 antibody Suppliers
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