Tyrphostin AG1433

Product Name: Tyrphostin AG1433
CAS No.: 168835-90-3
Chemical Name: Tyrphostin AG1433
Synonyms: 1,2-Benzenediol, 4-(6,7-dimethyl-2-quinoxalinyl)-;cytotoxicity,PDGFRβ,Tyrphostin AG 1433,AG-1433,Tyrphostin AG1433,VEGFR,AG 1433,kinases,Vascular endothelial growth factor receptor,SU 1433,Tyrphostin AG-1433,Platelet-derived growth factor receptor,angiogenesis,tyrosine,inhibit,VEGFR-2,Inhibitor,ATM,PDGFR,SU-1433
CBNumber: CB15854618
Molecular Formula: C16H14N2O2
Formula Weight: 266.29
MOL File: 168835-90-3.mol

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Tyrphostin AG1433 Property

Melting point:: 280-282 °C
Boiling point:: 490.9±45.0 °C(Predicted)
Density: 1.300±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 62.5 mg/mL (234.71 mM)
pka: 8.32±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0077937
Product name: TyrphostinAG1433
Purity: 99.20%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0077937
Product name: TyrphostinAG1433
Purity: 99.20%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0077937
Product name: TyrphostinAG1433
Purity: 99.20%
Packaging: 50mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-0077937
Product name: TyrphostinAG1433
Purity: 99.20%
Packaging: 100mg
Price: $1050
Updated: 2021/12/16

DC Chemicals

Product number: 012455
Product name: TyrphostinAG1433
Packaging: 003
Price: $1800
Updated: 2021/12/16

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Tyrphostin AG1433 Chemical Properties,Usage,Production

Biological Activity

Tyrphostin AG1433 (SU1433) is a tyrosine kinase inhibitor. It is also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor with IC50 of 5.0 μM and 9.3 μM, respectively. It prevents blood vessel formation.

in vivo

Chorion allantoic membrane (CAM) assays are used to determine the effects of the Flk-i inhibitors on angiogenesis. Tyrphostin AG1433 (SU1433) is prepared in methylcellulose pellets and applies to the CAMs of 4-6-day- old chicken embryos. Tyrphostin AG1433 prevents the formation of new yessels under the pellets.

target

Flk-1

< span> 9.3 μM (IC ₅₀ )

PDGFRβ

5 μM (IC ₅₀ )

Tyrphostin AG1433 Preparation Products And Raw materials

Raw materials

Preparation Products

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Tyrphostin AG1433 Suppliers

China 19 United States 3 Global 22

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
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ShangHai Biochempartner Co.,Ltd

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Zhengzhou Huiju Chemical Co., Ltd.

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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
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DC Chemicals

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Shandong Jirun Biomedical Technology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Hefei Mokai Pharmaceutical Technology Co., Ltd

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Bide Pharmatech Ltd.

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168835-90-3, Tyrphostin AG1433Related Search:

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1,2-Benzenediol, 4-(6,7-dimethyl-2-quinoxalinyl)-

cytotoxicity,PDGFRβ,Tyrphostin AG 1433,AG-1433,Tyrphostin AG1433,VEGFR,AG 1433,kinases,Vascular endothelial growth factor receptor,SU 1433,Tyrphostin AG-1433,Platelet-derived growth factor receptor,angiogenesis,tyrosine,inhibit,VEGFR-2,Inhibitor,ATM,PDGFR,SU-1433

168835-90-3