TYRPHOSTIN AG 1296
- Product Name
- TYRPHOSTIN AG 1296
- CAS No.
- 146535-11-7
- Chemical Name
- TYRPHOSTIN AG 1296
- Synonyms
- 1296;AG 1296;AG-1296;AG 1296;;TYRPHOSTIN AG 1296;TYRPHOSTIN AG 1296 USP/EP/BP;Tyrphostin AG 1296 (AG 1296);AG-1296 (Tyrphostin AG 1296);6,7-DIMETHOXY-3-PHENYLQUINOXALINE;6,7-DIMETHOXY-2-PHENYLQUINOXALINE;Quinoxaline,6,7-dimethoxy-2-phenyl-
- CBNumber
- CB7435034
- Molecular Formula
- C16H14N2O2
- Formula Weight
- 266.29
- MOL File
- 146535-11-7.mol
TYRPHOSTIN AG 1296 Property
- Boiling point:
- 420.2±40.0 °C(Predicted)
- Density
- 1.192±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- Soluble in DMSO.
- form
- White solid
- pka
- 0.48±0.30(Predicted)
- color
- Yellow
- Sensitive
- Light Sensitive
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- J67039
- Product name
- Tyrphostin AG-1296
- Purity
- 98%
- Packaging
- 5mg
- Price
- $182
- Updated
- 2021/12/16
- Product number
- 10010592
- Product name
- AG 1296
- Purity
- >98%
- Packaging
- 1mg
- Price
- $28
- Updated
- 2024/03/01
- Product number
- 10010592
- Product name
- AG 1296
- Purity
- >98%
- Packaging
- 5mg
- Price
- $117
- Updated
- 2024/03/01
- Product number
- 10010592
- Product name
- AG 1296
- Purity
- >98%
- Packaging
- 10mg
- Price
- $207
- Updated
- 2024/03/01
- Product number
- 10010592
- Product name
- AG 1296
- Purity
- >98%
- Packaging
- 25mg
- Price
- $448
- Updated
- 2024/03/01
TYRPHOSTIN AG 1296 Chemical Properties,Usage,Production
Description
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-
Uses
Tyrphostin AG 1296, is the platelet-derived growth factor receptor (PDGFR) inhibitor, which can causes growth inhibition in glioblastoma cells.
Definition
ChEBI: 6,7-dimethoxy-2-phenylquinoxaline is a quinoxaline derivative.
target
PDGFR
References
1) Kovalenko et al. (1997), Phosphorylation site-specific inhibition of platelet-derived growth factor beta-receptor autophosphorylation by the receptor blocking tyrphostin AG1296; Biochemistry, 36 6260 2) Krystal et al. (1997), Induction of apoptosis and inhibition of small cell lung cancer growth by the quinoxaline tyrphostins; Cancer Res., 57 220 3) Strutz et al. (2001), TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2); Kidney Int., 59 579
TYRPHOSTIN AG 1296 Preparation Products And Raw materials
Raw materials
Preparation Products
TYRPHOSTIN AG 1296 Suppliers
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View Lastest Price from TYRPHOSTIN AG 1296 manufacturers
- Product
- TYRPHOSTIN AG 1296 146535-11-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-25