ChemicalBook > CAS DataBase List > DOFETILIDE-D4

DOFETILIDE-D4

Product Name
DOFETILIDE-D4
CAS No.
1189700-56-8
Chemical Name
DOFETILIDE-D4
Synonyms
Tikosyn-d;Tikosyn-d4;UK 68789 D4; UK-68798-d4;DOFETILIDE-D4;N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-methanesulfonamide-d4;N-[4-(2-{[2-(4-methanesulfonamidophenoxy)(1,1,2,2-2H?)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide;Dofetilide D4Q: What is Dofetilide D4 Q: What is the CAS Number of Dofetilide D4 Q: What is the storage condition of Dofetilide D4 Q: What are the applications of Dofetilide D4
CBNumber
CB1648928
Molecular Formula
C19H27N3O5S2
Formula Weight
441.56478
MOL File
1189700-56-8.mol
More
Less

DOFETILIDE-D4 Property

Melting point:
130-1350C
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White
CAS DataBase Reference
1189700-56-8
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
26451
Product name
Dofetilide-d4
Packaging
500μg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
26451
Product name
Dofetilide-d4
Packaging
1mg
Price
$290
Updated
2024/03/01
Usbiological
Product number
D8079-25C
Product name
Dofetilide-d4
Packaging
1mg
Price
$460
Updated
2021/12/16
TRC
Product number
D525702
Product name
Dofetilide-d4
Packaging
10mg
Price
$1455
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D3782
Product name
Dofetilide-d4
Purity
98%
Packaging
1mg
Price
$950
Updated
2021/12/16
More
Less

DOFETILIDE-D4 Chemical Properties,Usage,Production

Description

Dofetilide-d4 is intended for use as an internal standard for the quantification of dofetilide by GC- or LC-MS. Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg. Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.

Chemical Properties

White Crystalline Solid

Uses

Potassium channel blocker.

Uses

Dofetilide-d4 is intended for use as an internal standard for the quantification of Dofitilide by GC- or LC-mass spectrometry.

DOFETILIDE-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DOFETILIDE-D4 Suppliers

Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2964
Advantage
58
Clearsynth Canada Inc.
Tel
+1.415.685.4395
Fax
+1.415.685.4395
Email
enquiry@clearsynth.com
Country
Canada
ProdList
912
Advantage
58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9577
Advantage
60
Chengdu Novel Biomedical Co., Ltd.
Tel
028-85255396 18302801538
Fax
028-85255396
Email
cdnovell@163.com
Country
China
ProdList
2310
Advantage
58
Shanghai ring qi biological technology co., LTD
Tel
13524106587
Email
sales@hq-chem.com
Country
China
ProdList
225
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Wuxi Minglu Medicine technology Co.,Ltd.
Tel
0510-88726693
Fax
0510-88726693
Email
3204601684@qq.com
Country
China
ProdList
2215
Advantage
58

1189700-56-8, DOFETILIDE-D4Related Search:


  • DOFETILIDE-D4
  • UK-68798-d4
  • N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-methanesulfonamide-d4
  • Tikosyn-d
  • Tikosyn-d4
  • UK 68789 D4
  • Dofetilide D4Q: What is Dofetilide D4 Q: What is the CAS Number of Dofetilide D4 Q: What is the storage condition of Dofetilide D4 Q: What are the applications of Dofetilide D4
  • N-[4-(2-{[2-(4-methanesulfonamidophenoxy)(1,1,2,2-2H?)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
  • 1189700-56-8
  • C19H23D4N3O5S2
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Isotope Labelled Compounds