ChemicalBook > CAS DataBase List > DOFETILIDE-D4

DOFETILIDE-D4

Product Name
DOFETILIDE-D4
CAS No.
1189700-56-8
Chemical Name
DOFETILIDE-D4
Synonyms
Tikosyn-d;Tikosyn-d4;UK 68789 D4; UK-68798-d4;DOFETILIDE-D4;N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-methanesulfonamide-d4;N-[4-(2-{[2-(4-methanesulfonamidophenoxy)(1,1,2,2-2H?)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide;Dofetilide D4Q: What is Dofetilide D4 Q: What is the CAS Number of Dofetilide D4 Q: What is the storage condition of Dofetilide D4 Q: What are the applications of Dofetilide D4
CBNumber
CB1648928
Molecular Formula
C19H27N3O5S2
Formula Weight
441.56478
MOL File
1189700-56-8.mol
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DOFETILIDE-D4 Property

Melting point:
130-1350C
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White
CAS DataBase Reference
1189700-56-8
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26451
Product name
Dofetilide-d4
Packaging
500μg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
26451
Product name
Dofetilide-d4
Packaging
1mg
Price
$290
Updated
2024/03/01
Usbiological
Product number
D8079-25C
Product name
Dofetilide-d4
Packaging
1mg
Price
$460
Updated
2021/12/16
TRC
Product number
D525702
Product name
Dofetilide-d4
Packaging
10mg
Price
$1455
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D3782
Product name
Dofetilide-d4
Purity
98%
Packaging
1mg
Price
$950
Updated
2021/12/16
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DOFETILIDE-D4 Chemical Properties,Usage,Production

Description

Dofetilide-d4 is intended for use as an internal standard for the quantification of dofetilide by GC- or LC-MS. Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg. Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.

Chemical Properties

White Crystalline Solid

Uses

Potassium channel blocker.

Uses

Dofetilide-d4 is intended for use as an internal standard for the quantification of Dofitilide by GC- or LC-mass spectrometry.

DOFETILIDE-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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DOFETILIDE-D4 Suppliers

Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58

1189700-56-8, DOFETILIDE-D4Related Search:


  • DOFETILIDE-D4
  • UK-68798-d4
  • N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-methanesulfonamide-d4
  • Tikosyn-d
  • Tikosyn-d4
  • UK 68789 D4
  • Dofetilide D4Q: What is Dofetilide D4 Q: What is the CAS Number of Dofetilide D4 Q: What is the storage condition of Dofetilide D4 Q: What are the applications of Dofetilide D4
  • N-[4-(2-{[2-(4-methanesulfonamidophenoxy)(1,1,2,2-2H?)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide
  • 1189700-56-8
  • C19H23D4N3O5S2
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Isotope Labelled Compounds