DOFETILIDE-D4
- Product Name
- DOFETILIDE-D4
- CAS No.
- 1189700-56-8
- Chemical Name
- DOFETILIDE-D4
- Synonyms
- Tikosyn-d;Tikosyn-d4;UK 68789 D4;UK-68798-d4;DOFETILIDE-D4;N-[4-[2-[Methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-methanesulfonamide-d4;N-[4-(2-{[2-(4-methanesulfonamidophenoxy)(1,1,2,2-2H?)ethyl](methyl)amino}ethyl)phenyl]methanesulfonamide;Dofetilide D4Q: What is Dofetilide D4 Q: What is the CAS Number of Dofetilide D4 Q: What is the storage condition of Dofetilide D4 Q: What are the applications of Dofetilide D4
- CBNumber
- CB1648928
- Molecular Formula
- C19H27N3O5S2
- Formula Weight
- 441.56478
- MOL File
- 1189700-56-8.mol
DOFETILIDE-D4 Property
- Melting point:
- 130-1350C
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White
- CAS DataBase Reference
- 1189700-56-8
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
H360May damage fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P330Rinse mouth.
P337+P313IF eye irritation persists: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 26451
- Product name
- Dofetilide-d4
- Packaging
- 500μg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 26451
- Product name
- Dofetilide-d4
- Packaging
- 1mg
- Price
- $290
- Updated
- 2024/03/01
- Product number
- D8079-25C
- Product name
- Dofetilide-d4
- Packaging
- 1mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- D525702
- Product name
- Dofetilide-d4
- Packaging
- 10mg
- Price
- $1455
- Updated
- 2021/12/16
- Product number
- D3782
- Product name
- Dofetilide-d4
- Purity
- 98%
- Packaging
- 1mg
- Price
- $950
- Updated
- 2021/12/16
DOFETILIDE-D4 Chemical Properties,Usage,Production
Description
Dofetilide-d4 is intended for use as an internal standard for the quantification of dofetilide by GC- or LC-MS. Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg. Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.
Chemical Properties
White Crystalline Solid
Uses
Potassium channel blocker.
Uses
Dofetilide-d4 is intended for use as an internal standard for the quantification of Dofitilide by GC- or LC-mass spectrometry.
DOFETILIDE-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
DOFETILIDE-D4 Suppliers
- Tel
- --
- Fax
- --
- @pharmaffiliates.com
- Country
- India
- ProdList
- 6754
- Advantage
- 58
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- standards@synzeal.com
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- India
- ProdList
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- Tel
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- mktg@pharmaffiliates.com
- Country
- India
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- 6739
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