3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
- Product Name
- 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
- CAS No.
- 380238-10-8
- Chemical Name
- 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE
- Synonyms
- AKOS BBS-00006677;5-Methyl-2-[2-(trifluoromethyl)phenyl]pyrazol-3-amine;3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE;5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE;1H-Pyrazol-5-amine, 3-methyl-1-[2-(trifluoromethyl)phenyl]-;5-Amino-3-methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazole, 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)benzotrifluoride
- CBNumber
- CB1667679
- Molecular Formula
- C11H10F3N3
- Formula Weight
- 241.21
- MOL File
- Mol file
3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Property
- Boiling point:
- 342.7±42.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 3.37±0.10(Predicted)
- form
- powder
- color
- Off-white
Safety
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M332168
- Product name
- 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1h-pyrazol-5-amine
- Packaging
- 250mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 101930
- Product name
- 3-Methyl-1-(2-(trifluoromethyl)-phenyl)-1H-pyrazol-5-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $357
- Updated
- 2021/12/16
- Product number
- 3H30-3-1R
- Product name
- 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine
- Packaging
- 1g
- Price
- $244
- Updated
- 2021/12/16
- Product number
- HCH0054282
- Product name
- 5-METHYL-2-(2-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $910.76
- Updated
- 2021/12/16
- Product number
- 101930
- Product name
- 3-Methyl-1-(2-(trifluoromethyl)-phenyl)-1H-pyrazol-5-amine
- Purity
- 95%
- Packaging
- 5g
- Price
- $983
- Updated
- 2021/12/16
3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Chemical Properties,Usage,Production
Synthesis
1118-61-2
365-34-4
380238-10-8
GENERAL METHOD: 3-Aminobut-2-enenenitrile (10 mmol) was added to a suspension of (2-(trifluoromethyl)phenyl)hydrazine (10 mmol) in 12 M HCl-H2O (12 mL, 1:3 v/v). The reaction mixture was heated to reflux for 12 h, subsequently cooled to room temperature and neutralized with 2.5 M NaOH solution. The reaction mixture was extracted with dichloromethane (3 x 30 mL). The organic phases were combined, washed with saturated saline (20 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was ground with hexane to give a solid product, which was separated by filtration. If necessary, the product was purified by column chromatography.
References
[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 11, p. 3429 - 3445
[2] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 136-137
[3] Journal of Combinatorial Chemistry, 2010, vol. 12, # 4, p. 510 - 517
3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE Suppliers
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View Lastest Price from 3-METHYL-1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-5-AMINE manufacturers
- Product
- 3-Methyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine 380238-10-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2020-01-10