Sulforaphene

Pharmacological action Cancer Treatment

Product Name: Sulforaphene
CAS No.: 592-95-0
Chemical Name: Sulforaphene
Synonyms: sativin;RAPHANIN;Sul aphene;sulforaphene;Sulphoraphen;L-SULFORAPHENE;S-SULFORAPHENE;L-SULPHORAPHENE;SULFORAPHENE, L-;Sulforaphen (6CI)
CBNumber: CB1686355
Molecular Formula: C6H9NOS2
Formula Weight: 175.27
MOL File: 592-95-0.mol

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Sulforaphene Property

alpha: D19 -107° (c = 1.37 in chloroform); D14 -136° (c = 1.38 in alcohol)
Boiling point:: bp0.015 125-130°
Density: 1.16±0.1 g/cm3(Predicted)
storage temp.: Refrigerator, Under inert atmosphere
solubility: Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethylacetate (Slightly)
form: Slightly yellowish liquid.
color: Colourless to Yellow
CAS DataBase Reference: 592-95-0

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17152
Product name: L-Sulforaphene
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 17152
Product name: L-Sulforaphene
Purity: ≥98%
Packaging: 5mg
Price: $166
Updated: 2024/03/01

Cayman Chemical

Product number: 17152
Product name: L-Sulforaphene
Purity: ≥98%
Packaging: 10mg
Price: $275
Updated: 2024/03/01

TRC

Product number: S699440
Product name: Sulforaphene
Packaging: 10mg
Price: $185
Updated: 2021/12/16

ChemScene

Product number: CS-0022676
Product name: Sulforaphene
Purity: 98.01%
Packaging: 10mg
Price: $202
Updated: 2021/12/16

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Sulforaphene Chemical Properties,Usage,Production

Pharmacological action

Sulforaphene, or raphanin, is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage. It was first described by G. Ivanovics and S. Horvath in 1947. Sulforaphene inhibits activity of viruses, some fungi and various bacteria including Staphylococcus, Streptococcus, Pneumococcus and Escherichia coli. The effect is stronger against Gram-positive than Gram-negative bacteria and against DNA than RNA viruses; it is suppressed by serum and by sulfur compounds such as hydrogen sulfide, mercaptoacetic acid, cystine and glutathione. The antibacterial, antifungal and antiviral effects from consuming radishes were recognized in traditional Chinese medicine. However, in the abstract to his 1947 paper, Ivanovics noted that because sulforaphene is highly toxic, it did not "hold the promise of a useful therapeutic agent".

Cancer Treatment

Sulforaphene may be a potential anti-triple negative breast cancer natural compound and its antiproliferation effects may be mediated by tumor suppressor Egr1; it has chemotherapeutic potential, it promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation; it enhances radiosensitivity of hepatocellular carcinoma through suppression of the NF-κB pathway. Sulforaphene has anti-proliferative and antibacterial properties. Sulforaphene also has herbicidal activity, the ED50 of it against velvetleaf seedlings was approximately 2×10^-4 M.

Uses

Sulforaphene is an extract from the seeds of Raphanus sativus and displays anti-inflammatory and anti-cancer activity.

Synthesis Reference(s)

Tetrahedron, 22, p. 2139, 1966 DOI: 10.1016/S0040-4020(01)82133-5

Sulforaphene Preparation Products And Raw materials

Raw materials

Preparation Products

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Sulforaphene Suppliers

China 114 Germany 1 India 1 Switzerland 1 United Kingdom 4 United States 18 Global 139

TargetMol Chemicals Inc.

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Aladdin Scientific

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TargetMol Chemicals Inc.

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Cayman Chemical Company

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Quality Phytochemicals LLC

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ChromaDex

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View Lastest Price from Sulforaphene manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Sulforaphene 592-95-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: >98%
Supply Ability: 1000 kg
Release date: 2024-04-25

Shanghai Standard Technology Co., Ltd.

Product: Sulforaphene 592-95-0
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-05-12

Career Henan Chemical Co

Product: Sulforaphene 592-95-0
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-12

592-95-0, SulforapheneRelated Search:

Fluorescein isothiocyanate Tiglic aldehyde 1,4-PHENYLENE DIISOTHIOCYANATE Phenyl isothiocyanate GLUCOTROPAEOLIN Z-LIGUSTILIDE ALPHA-CARYOPHYLLENE Hydroxycitric acid Xanthiside Muscone ISOQUERCITRIN ERUCIN Allyl isothiocyanate ISOTHIOCYANIC ACID 3-BUTEN-1-YL ESTER SULFORAPHENE, L-(RG) Sulforaphene ISOTHIOCYANATE, POLYMER-BOUND, 200-400

(E)-4-Isothiocyanato-1-(methylsulfinyl)-1-butene

sativin

sulforaphene

S-Sulforaphenefromradishseeds

SULFORAPHANE, DL-(SH)

1-Butene,4-isothiocyanato-1-(Methylsulfinyl)-

L-SULFORAPHENE

L-SULPHORAPHENE

4-isothiocyanato-1-(methylsulfinyl)-1-buten

4-isothiocyanato-1-(methylsulfinyl)-1-butene

isothiocyanicacid,4-(methylsulfinyl)-3-butenylester

Sul aphene

4-Methylsulfinylbut-3-enyl isothiocyanate

Isothiocyanicacid, 4-(methylsulfinyl)-3-butenyl ester (7CI,8CI)

Sulforaphen (6CI)

SULFORAPHENE, L-

S-SULFORAPHENE

RAPHANIN

(-)4 ISOTHIOCYANATO-4R-METHYLSULFINYL)-1-BUTENE

4-ISOTHIOCYANATO-4R(METHYLSULFINYL)-1-BUTENE

(-)4-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-1-BUTENE

(-)-4-ISOTHIOCYANATO-(1R)-(METHYLSULFINYL)-1-BUTENE

(-)-4-ISOTHIOCYANATO-(1S)-(METHYLSUFINYL)-1-BUTENE

Sulforaphene USP/EP/BP

Sulphoraphen

4-Isothiocyanato-1-(methylsulfinyl)but-1-ene

592-95-0

C6H9NOS2

Miscellaneous Natural Products