2,4-DIMETHYL-6-HYDROXYPYRIMIDINE

Product Name: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE
CAS No.: 6622-92-0
Chemical Name: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE
Synonyms: 4-Hydroxy-2,6-dimethyL;2,6-DIMETHYL-4-PYRIMIDINO;2,6-dimethlpyrimidin-4-ol;6-dimethyl pyrimidin-4-ol;2,6-DIMETHYLPYRIMIDIN-4-OL;2,6-DIMETHYL-4-PYRIMIDINOL;2,4-Dimethyl-6-pyrimidinol;2,4-Dimethylpyrimidine-6-ol;2,6-Dimethylpyrimidine-4-ol;2,6-dimethylpyrimidine-4--one
CBNumber: CB1692244
Molecular Formula: C6H8N2O
Formula Weight: 124.14
MOL File: 6622-92-0.mol

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2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Property

Melting point:: 198.5-200 °C (lit.)
Boiling point:: 230.92°C (rough estimate)
Density: 1.1683 (rough estimate)
refractive index: 1.5378 (estimate)
storage temp.: Inert atmosphere,Room Temperature
form: Crystalline Needles
pka: 9.87±0.50(Predicted)
color: White
BRN: 114324
InChI: InChI=1S/C6H8N2O/c1-4-3-6(9)8-5(2)7-4/h3H,1-2H3,(H,7,8,9)
InChIKey: UQFHLJKWYIJISA-UHFFFAOYSA-N
SMILES: C1(C)=NC(C)=CC(=O)N1
CAS DataBase Reference: 6622-92-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29335995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D2579
Product name: 2,4-Dimethyl-6-hydroxypyrimidine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $97
Updated: 2025/07/31

TCI Chemical

Product number: D2579
Product name: 2,4-Dimethyl-6-hydroxypyrimidine
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $317
Updated: 2025/07/31

TRC

Product number: D480258
Product name: 2,6-Dimethyl-1H-pyrimidin-4-one
Packaging: 1g
Price: $45
Updated: 2021/12/16

TRC

Product number: D480258
Product name: 2,6-Dimethyl-1H-pyrimidin-4-one
Packaging: 10g
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-W6
Product name: 2,4-Dimethyl-6-hydroxypyrimidine
Packaging: 5G
Price: $24
Updated: 2021/12/16

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2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

white crystalline needles

Synthesis

124-42-5

141-97-9

6622-92-0

General procedure for the synthesis of 2,4-dimethyl-6-hydroxypyrimidines from acetamidine hydrochloride and ethyl acetoacetate: to a solution of sodium ethanolate (10.5 g, 154 mmol) in ethanol (200 mL) was added ethyl 3-oxobutanoate (10.0 g, 77 mmol) and acetamidine hydrochloride (7.23 g, 77 mmol) sequentially. The reaction mixture was heated to reflux for 20 hours. After completion of the reaction, water (10 mL) was added to the mixture. The reaction mixture was concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography (silica gel as stationary phase, dichloromethane/methanol=15:1 as mobile phase) to afford 2,6-dimethylpyrimidin-4-ol as a yellow solid (3.43 g, 36% yield).LRMS (M+H+) m/z: Calculated value 124.06; measured value 124.

References

[1] Patent: WO2013/75083, 2013, A1. Location in patent: Paragraph 00374; 00375
[2] Synthesis (Germany), 2016, vol. 48, # 23, p. 4246 - 4252
[3] Patent: US2012/95031, 2012, A1. Location in patent: Page/Page column 159-160

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Suppliers

Americas 1 Belgium 1 China 148 Europe 2 Germany 2 India 10 Japan 4 Slovakia 1 Switzerland 1 The Netherlands 4 United Kingdom 12 United States 27 Global 213

Shanghai Arbor Chemical Co., Ltd.

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View Lastest Price from 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE 6622-92-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-09

Career Henan Chemical Co

Product: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE 6622-92-0
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-23

6622-92-0, 2,4-DIMETHYL-6-HYDROXYPYRIMIDINERelated Search:

N-NONANE 6-(Chloromethyl)-2-phenylpyrimidin-4-ol 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Diazinon 4,6-Dimethyl-2-hydroxypyrimidine 5-Pyrimidinol, 4,6-dimethyl- (6CI,9CI) 4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE 97+%,4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE 4,5-Dimethyl-2-pyrimidinol 2-AMINO-5,6-DIMETHYL-4-HYDROXYPYRIMIDINE 2-(TERT-BUTYL)-6-(CHLOROMETHYL)PYRIMIDIN-4-OL 2-(4-PYRIDYL)-4-HYDROXY-6-MENTHYL PYRIMIDINE 5-CHLORO-6-METHYL-2-(2-PYRIDYL)PYRIMIDIN-4-OL 4-HYDROXY-6-METHOXYMETHYL-2-METHYLPYRIMIDINE 2-methylamino-5,6-dimethyl-4-hydroxypyrimidine 2-Ethylamino-4,5-dimethyl-6-hydroxypyrimidine BUTTPARK 12\02-33 BUTTPARK 74\02-43 O,O-DIETHYL O-(6-METHYL-2-PHENYL-5-[3-(TRIFLUOROMETHYL)PHENOXY]PYRIMIDIN-4-YL) PHOSPHOTHIOATE

6-HYDROXY-2,4-DIMETHYLPYRIMIDINE

4-HYDROXY-2,6-DIMETHYLPYRIMIDINE

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE

2,6-DIMETHYLPYRIMIDIN-4-OL

2,6-DIMETHYL-4-PYRIMIDINO

2,6-DIMETHYL-4-PYRIMIDINOL

2,6-DIMETHYL-4-HYDROXYPYRIMIDINE

2,6-Dimethyl-4(3H)-pyrimidinone

2,6-dimethyl-1,4-dihydropyrimidin-4-one

2,6-Dimethyl-4-pyrimidinol 6-Hydroxy-2,4-dimethylpyrimidine

2,6-DiMethylpyriMidin-4(3H)-One

hydroxy-2,6-diMethylpyriMidine

2,4-Dimethyl-6-hydroxypyrimidine, 2,6-Dimethyl-4-pyrimidinol

2,4-Dimethylpyrimidine-6-ol

2,6-Dimethylpyrimidin-4(1H)-one

2,6-Dimethylpyrimidine-4(3H)-one

2,6-Dimethylpyrimidine-4-ol

2,6-Dimethylpyrimidin-4-ol, 2,4-Dimethyl-6-hydroxy-1,3-diazine

2,4-Dimethyl-6-pyrimidinol

6-hydroxy-2,4-dimethylyrimidine

2,6-dimethyl-1H-pyrimidin-4-one

4-Hydroxy-2,6-dimethylpyrimidine, >=99%

4(1H)-Pyrimidinone, 2,6-dimethyl- (8CI,9CI)

2,4-Dimethyl-6-hydroxypyrimidine, 99+%

2,4-Dimethyl-6-hydroxypyrimidine&gt

4-Hydroxy-2,6-dimethyL

4(3H)-Pyrimidinone, 2,6-dimethyl-

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE ISO 9001：2015 REACH

2,6-dimethylpyrimidine-4--one

2,6-Dimethyl-4(1H)-pyrimidinone

2,6-dimethlpyrimidin-4-ol

6-dimethyl pyrimidin-4-ol

6622-92-0

Building Blocks

Heterocyclic Building Blocks

Pyrimidines

alcohol

PYRIMIDINE

APIs & Intermediate