ChemicalBook > CAS DataBase List > 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE

Product Name: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE
CAS No.: 6622-92-0
Chemical Name: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE
Synonyms: 4-Hydroxy-2,6-dimethyL;2,6-DIMETHYL-4-PYRIMIDINO;2,6-dimethlpyrimidin-4-ol;6-dimethyl pyrimidin-4-ol;2,6-DIMETHYLPYRIMIDIN-4-OL;2,6-DIMETHYL-4-PYRIMIDINOL;2,4-Dimethyl-6-pyrimidinol;2,4-Dimethylpyrimidine-6-ol;2,6-Dimethylpyrimidine-4-ol;2,6-dimethylpyrimidine-4--one
CBNumber: CB1692244
Molecular Formula: C6H8N2O
Formula Weight: 124.14
MOL File: 6622-92-0.mol

Less

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Property

Melting point:: 198.5-200 °C (lit.)
Boiling point:: 230.92°C (rough estimate)
Density: 1.1683 (rough estimate)
refractive index: 1.5378 (estimate)
storage temp.: Inert atmosphere,Room Temperature
form: Crystalline Needles
pka: 9.87±0.50(Predicted)
color: White
BRN: 114324
InChI: InChI=1S/C6H8N2O/c1-4-3-6(9)8-5(2)7-4/h3H,1-2H3,(H,7,8,9)
InChIKey: UQFHLJKWYIJISA-UHFFFAOYSA-N
SMILES: C1(C)=NC(C)=CC(=O)N1
CAS DataBase Reference: 6622-92-0(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29335995

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: D2579
Product name: 2,4-Dimethyl-6-hydroxypyrimidine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $97
Updated: 2025/07/31

TCI Chemical

Product number: D2579
Product name: 2,4-Dimethyl-6-hydroxypyrimidine
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $317
Updated: 2025/07/31

TRC

Product number: D480258
Product name: 2,6-Dimethyl-1H-pyrimidin-4-one
Packaging: 1g
Price: $45
Updated: 2021/12/16

TRC

Product number: D480258
Product name: 2,6-Dimethyl-1H-pyrimidin-4-one
Packaging: 10g
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-W6
Product name: 2,4-Dimethyl-6-hydroxypyrimidine
Packaging: 5G
Price: $24
Updated: 2021/12/16

Less

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

white crystalline needles

Synthesis

124-42-5

141-97-9

6622-92-0

General procedure for the synthesis of 2,4-dimethyl-6-hydroxypyrimidines from acetamidine hydrochloride and ethyl acetoacetate: to a solution of sodium ethanolate (10.5 g, 154 mmol) in ethanol (200 mL) was added ethyl 3-oxobutanoate (10.0 g, 77 mmol) and acetamidine hydrochloride (7.23 g, 77 mmol) sequentially. The reaction mixture was heated to reflux for 20 hours. After completion of the reaction, water (10 mL) was added to the mixture. The reaction mixture was concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography (silica gel as stationary phase, dichloromethane/methanol=15:1 as mobile phase) to afford 2,6-dimethylpyrimidin-4-ol as a yellow solid (3.43 g, 36% yield).LRMS (M+H+) m/z: Calculated value 124.06; measured value 124.

References

[1] Patent: WO2013/75083, 2013, A1. Location in patent: Paragraph 00374; 00375
[2] Synthesis (Germany), 2016, vol. 48, # 23, p. 4246 - 4252
[3] Patent: US2012/95031, 2012, A1. Location in patent: Page/Page column 159-160

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Suppliers

Americas 1 Belgium 1 China 148 Europe 2 Germany 2 India 10 Japan 4 Slovakia 1 Switzerland 1 The Netherlands 4 United Kingdom 12 United States 27 Global 213

Shanghai Arbor Chemical Co., Ltd.

Tel: 021-60451683 15021268886
Fax: +86-21-60451682
Email: sales@arborchemical.com
Country: China
ProdList: 896
Advantage: 55

SiChuang NanBu Honesty Technology Co., Ltd.

Tel: 0838-5675166 15883665058
Fax: 0838-5675535
Email: nbcxkj@126.com
Country: China
ProdList: 918
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Santai Labs, Inc.

Tel: 519-85601385
Fax: +86 519 8560 1389
Email: marketing@santailabs.com
Country: China
ProdList: 891
Advantage: 62

RYSS TECH LTD

Tel: 400-188-0725 +86 21 34310725 13611771617
Fax: +86 21 34311076
Country: China
ProdList: 2002
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai ChriChem Co., Ltd.

Tel: 021-54880687
Fax: 021-54880687
Country: China
ProdList: 511
Advantage: 55

Chimica Laboratories Co., Ltd

Tel: 0086-573-82585213
Fax: 0086-573-82585233
Email: bai@chimicalabs.com
Country: China
ProdList: 861
Advantage: 64

Taizhou Tongxin Bio-Tech Co., Ltd

Tel: 0523-86818997 18652728585
Email: sales@allyrise.com
Country: China
ProdList: 2966
Advantage: 60

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5872
Advantage: 58

Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd.

Tel: 19943855286
Fax: 0371-53392065
Email: triz-4@trizpharma.cn
Country: China
ProdList: 1936
Advantage: 56

Changzhou Qinuo Chemical Co., Ltd.Co., Ltd.

Tel: 0519-0519-83812535
Email: sales@qinuochem.com
Country: China
ProdList: 287
Advantage: 60

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Shanghai Tombiopharma Chemical Co. Ltd.

Tel: 13391076197
Email: tombiopharma@163.com
Country: China
ProdList: 4987
Advantage: 55

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Giant chemicals

Tel: 028-85434334 18108076537
Fax: QQ：245797092
Email: market@gianthx.com
Country: China
ProdList: 4505
Advantage: 56

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Nanjing Vital Chemical Co., Ltd.

Tel: 025-87193546 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 9021
Advantage: 60

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Nanjing XiLang Chemical Products Co., Ltd.

Tel: 18936048580
Email: chemxilang@163.com
Country: China
ProdList: 3909
Advantage: 58

Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003
Email: info@qiaochem.com
Country: China
ProdList: 6059
Advantage: 65

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Nanijing m&m biotechnology Co. ,Ltd.

Tel: 025-87782433 18021532344
Fax: 025-87782433
Email: 1345332203@qq.com
Country: China
ProdList: 4134
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

BIO-PHARMACY (Wuhan) Co., Ltd.

Tel: 0711-5919292 15307133740
Fax: 0711-5919292
Email: 3451683016@qq.com
Country: China
ProdList: 1069
Advantage: 58

Combiphos (Shanghai) Biological Technology Co., Ltd.

Tel: 021-65232103 17602124823
Email: combiphos@vip.qq.com
Country: China
ProdList: 30000
Advantage: 58

Chemtarget Technologies Co., Ltd

Tel: 0816-2541516 13548425599
Fax: +86-816-2538509
Email: 626079707@qq.com
Country: China
ProdList: 163
Advantage: 58

Less

View Lastest Price from 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE 6622-92-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-09

Career Henan Chemical Co

Product: 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE 6622-92-0
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-23

6622-92-0, 2,4-DIMETHYL-6-HYDROXYPYRIMIDINERelated Search:

N-NONANE 6-(Chloromethyl)-2-phenylpyrimidin-4-ol 2,4-DIMETHYL-6-HYDROXYPYRIMIDINE Diazinon 4,6-Dimethyl-2-hydroxypyrimidine 5-Pyrimidinol, 4,6-dimethyl- (6CI,9CI) 4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE 97+%,4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE 4,5-Dimethyl-2-pyrimidinol 2-AMINO-5,6-DIMETHYL-4-HYDROXYPYRIMIDINE 2-(TERT-BUTYL)-6-(CHLOROMETHYL)PYRIMIDIN-4-OL 2-(4-PYRIDYL)-4-HYDROXY-6-MENTHYL PYRIMIDINE 5-CHLORO-6-METHYL-2-(2-PYRIDYL)PYRIMIDIN-4-OL 4-HYDROXY-6-METHOXYMETHYL-2-METHYLPYRIMIDINE 2-methylamino-5,6-dimethyl-4-hydroxypyrimidine 2-Ethylamino-4,5-dimethyl-6-hydroxypyrimidine BUTTPARK 12\02-33 BUTTPARK 74\02-43 O,O-DIETHYL O-(6-METHYL-2-PHENYL-5-[3-(TRIFLUOROMETHYL)PHENOXY]PYRIMIDIN-4-YL) PHOSPHOTHIOATE

6-HYDROXY-2,4-DIMETHYLPYRIMIDINE

4-HYDROXY-2,6-DIMETHYLPYRIMIDINE

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE

2,6-DIMETHYLPYRIMIDIN-4-OL

2,6-DIMETHYL-4-PYRIMIDINO

2,6-DIMETHYL-4-PYRIMIDINOL

2,6-DIMETHYL-4-HYDROXYPYRIMIDINE

2,6-Dimethyl-4(3H)-pyrimidinone

2,6-dimethyl-1,4-dihydropyrimidin-4-one

2,6-Dimethyl-4-pyrimidinol 6-Hydroxy-2,4-dimethylpyrimidine

2,6-DiMethylpyriMidin-4(3H)-One

hydroxy-2,6-diMethylpyriMidine

2,4-Dimethyl-6-hydroxypyrimidine, 2,6-Dimethyl-4-pyrimidinol

2,4-Dimethylpyrimidine-6-ol

2,6-Dimethylpyrimidin-4(1H)-one

2,6-Dimethylpyrimidine-4(3H)-one

2,6-Dimethylpyrimidine-4-ol

2,6-Dimethylpyrimidin-4-ol, 2,4-Dimethyl-6-hydroxy-1,3-diazine

2,4-Dimethyl-6-pyrimidinol

6-hydroxy-2,4-dimethylyrimidine

2,6-dimethyl-1H-pyrimidin-4-one

4-Hydroxy-2,6-dimethylpyrimidine, >=99%

4(1H)-Pyrimidinone, 2,6-dimethyl- (8CI,9CI)

2,4-Dimethyl-6-hydroxypyrimidine, 99+%

2,4-Dimethyl-6-hydroxypyrimidine&gt

4-Hydroxy-2,6-dimethyL

4(3H)-Pyrimidinone, 2,6-dimethyl-

2,4-DIMETHYL-6-HYDROXYPYRIMIDINE ISO 9001：2015 REACH

2,6-dimethylpyrimidine-4--one

2,6-Dimethyl-4(1H)-pyrimidinone

2,6-dimethlpyrimidin-4-ol

6-dimethyl pyrimidin-4-ol

6622-92-0

Building Blocks

Heterocyclic Building Blocks

Pyrimidines

alcohol

PYRIMIDINE

APIs & Intermediate