ChemicalBook > CAS DataBase List > 3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE

3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE

Product Name
3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE
CAS No.
93246-53-8
Chemical Name
3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE
Synonyms
3-FLUORO-4-MORPHOLINOANILINE;Linezolid AMine IMpurity;AKOS B033533;TIMTEC-BB SBB010944;Linezolid Impurity 28;Linezolid Intermediate 1;3-Fluoro-4-morpholinoanili;3-Fluoro-4-morpholin-4-yl-;3-FLUORO-4-MORPHOLIN-ANILINE;Linezolid Phenylamine Impurity
CBNumber
CB1698428
Molecular Formula
C10H13FN2O
Formula Weight
196.22
MOL File
93246-53-8.mol
More
Less

3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE Property

Melting point:
121-123°C
Boiling point:
364.9±42.0 °C(Predicted)
Density 
1.232±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform, Methanol
form 
Solid
pka
6.53±0.40(Predicted)
color 
Off-White to Brown
InChI
InChI=1S/C10H13FN2O/c11-9-7-8(12)1-2-10(9)13-3-5-14-6-4-13/h1-2,7H,3-6,12H2
InChIKey
FQGIBHQUVCGEAC-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(N2CCOCC2)C(F)=C1
CAS DataBase Reference
93246-53-8(CAS DataBase Reference)
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
F0849
Product name
3-Fluoro-4-morpholinoaniline
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$89
Updated
2025/07/31
TCI Chemical
Product number
F0849
Product name
3-Fluoro-4-morpholinoaniline
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$269
Updated
2025/07/31
TRC
Product number
F595895
Product name
3-Fluoro-4-(4-morpholinyl)Benzenamine
Packaging
1g
Price
$50
Updated
2021/12/16
Matrix Scientific
Product number
051328
Product name
3-Fluoro-4-(4-morpholinyl)aniline
Packaging
25g
Price
$34
Updated
2021/12/16
AK Scientific
Product number
W9598
Product name
3-Fluoro-4-morpholinoaniline
Packaging
25g
Price
$45
Updated
2021/12/16
More
Less

3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE Chemical Properties,Usage,Production

Chemical Properties

Brown Solid

Uses

Intermediate in the synthesis of Linezolid (L466500).

Definition

ChEBI: 3-Fluoro-4-morpholinoaniline is a member of morpholines.

Synthesis

2689-39-6

93246-53-8

The general procedure for the synthesis of 3-fluoro-4-(4-morpholinyl)aniline from 3-fluoro-4-(4-morpholinyl)nitrobenzene was as follows: 4-(2-fluoro-4-nitrophenyl)morpholine D1 (42.6 g, 0.19 mol) was dissolved in ethanol (1.2 L), 10% Pd/C catalyst (4 g) was added, and hydrogenation was carried out at standard temperature and pressure (STP) for 18 hours. Upon completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was evaporated under vacuum to afford the target product 3-fluoro-4-(4-morpholinyl)aniline (36.9 g, 100% yield) as a colorless solid. The structure of the product was confirmed by 1H NMR (CDCl3): δ 2.96 (4H, m), 3.55 (2H, br s), 3.84 (4H, m), 6.41 (2H, m), 6.79 (1H, m).

References

[1] Patent: WO2005/58317, 2005, A1. Location in patent: Page/Page column 35
[2] Patent: WO2005/58885, 2005, A2. Location in patent: Page/Page column 33
[3] Patent: WO2005/75461, 2005, A1. Location in patent: Page/Page column 100
[4] Patent: WO2006/2956, 2006, A1. Location in patent: Page/Page column 31
[5] Journal of Medicinal Chemistry, 2018, vol. 61, # 9, p. 4052 - 4066

3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE Suppliers

Americas 1 Belgium 1 Canada 2 China 304 Europe 2 France 1 Germany 3 India 33 Japan 1 United Kingdom 6 United States 37 Global 391
Gansu Songsheng Pharmaceutical Co. , Ltd.
Tel
13705130158
Email
sales@unitechemical.com
Country
China
ProdList
136
Advantage
58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60189726 18812034280
Fax
86-22-60979672
Email
188120342808@163.com
Country
China
ProdList
142
Advantage
61
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
More
Less

View Lastest Price from 3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE 93246-53-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98
Supply Ability
10000KGS
Release date
2025-12-05
Hebei Chuanghai Biotechnology Co., Ltd
Product
3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE 93246-53-8
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-22
Longyan Tianhua Biological Technology Co., Ltd
Product
3-FLUORO-4-MORPHOLIN-ANILINE 93246-53-8
Price
US $21.00/Kg/Bag
Min. Order
25Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2020-11-02

93246-53-8, 3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINERelated Search:

Linezolid 4-(2-FLUORO-4-NITRO-PHENYL)-MORPHOLINE (R)-[3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate O-descarbonyl O-Acetyl Linezolid Linezolid Impurity 33 Linezolid Impurity 56 DeacetaMide Linezolid PhthaliMide Linezolid IMpurity D HCl Linezolid Related Impurity 1 Desacetyl-N,O-descarbonyl Linezolid Linezolid Impurity 21 Linezolid Diphthalimide Linezolid Impurity 37 Linezolid Impurity 24 Linezolid Impurity 25 Linezolid Impurity 34 Linezolid Impurity 57 (R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone

  • AKOS B033533
  • 3-FLUORO-4-(4-MORPHOLINYL)-BENZEAMINE
  • 3-FLUORO-4-(4-MORPHOLINYL)-BENZENAMINE
  • 3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE
  • 3-FLUORO-4-MORPHOLIN-ANILINE
  • 3-FLUORO-4-MORPHOLINOANILINE
  • 3-FLUORO-4-MORPHOLINOPHENYLAMINE
  • TIMTEC-BB SBB010944
  • Linazolamide intermediate B impurity 4
  • 3-Fluoro-4-(4-morpholinyl)aniline
  • 3-fluoro-4-morpholin-4-ylaniline
  • 3-fluoro-4-morpholinobenzenamine
  • 3-fluoro-4-(4-morpholinyl)aniline(SALTDATA: HCl)
  • Linezolid Intermediate 1
  • 3- fluorine-4-(4- Morphine groups)aniline
  • N-(4-AMino-2-fluorophenyl)Morpholine.
  • 4-(2-Fluoro-4-aminophenyl)morpholine
  • BenzenaMine, 3-fluoro-4-(4-Morpholinyl)-
  • Linezolid AMine IMpurity
  • 3-FLUORO3-FLUORO-4-MORPHOLIN-4-YL-PHENYLAMINE
  • 3-Fluoro-4-morpholinoanili
  • Linezolid Impurity 28
  • 3-Fluoro-4-morpholinoaniline&gt
  • Linezolid Phenylamine Impurity
  • 3-Fluoro-4-morpholinoaniline, 98+%
  • 3-Fluoro-4-(4-morpholinyl)-benzamine
  • 3-Fluoro-4-morpholin-4-yl-
  • 3-Fluoro-4-morpholinoaniline 98%
  • 93246-53-8
  • 93246-53-81
  • C10H13FN2O
  • linezolid intermediate
  • Agonist