Phenelzine Sulfate

Product Name: Phenelzine Sulfate
CAS No.: 156-51-4
Chemical Name: Phenelzine Sulfate
Synonyms: wl7;p1531;ep-411;alazin;kalgan;S-1544;alazine;alacine;mao-rem;N-1544A
CBNumber: CB1719066
Molecular Formula: C8H14N2O4S
Formula Weight: 234.27
MOL File: 156-51-4.mol

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Phenelzine Sulfate Property

Melting point:: 166.5-167.5 °C
storage temp.: 2-8°C
solubility: Freely soluble in water; practically insoluble in ethanol (96%) and in ether .
form: A solid
color: White to off-white
Merck: 13,7300
CAS DataBase Reference: 156-51-4
IARC: 3 (Vol. 24, Sup 7) 1987

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Safety

Hazard Codes: Xn
Risk Statements: 22
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: MV8750000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 2928002500
Toxicity: LD50 orally in mice: 156 mg/kg (Gylys)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P6777
Product name: Phenelzine sulfate salt
Packaging: 5g
Price: $407
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1517006
Product name: Phenelzine sulfate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $436
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP1166
Product name: Phenelzine sulfate
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 100MG
Price: $231
Updated: 2023/01/07

Cayman Chemical

Product number: 23956
Product name: Phenelzine (sulfate)
Purity: ≥98%
Packaging: 250mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 23956
Product name: Phenelzine (sulfate)
Purity: ≥98%
Packaging: 500mg
Price: $120
Updated: 2024/03/01

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Phenelzine Sulfate Chemical Properties,Usage,Production

Chemical Properties

A white powder or pearly platelets.

Originator

Nardil ,Parke Davis, US ,1959

Uses

antihistaminic

Uses

Phenelzine Sulfate is a hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidep ressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders.

Definition

ChEBI: Phenelzine sulfate is an organic molecular entity.

Manufacturing Process

To a refluxing solution containing 147.5 grams of 85% hydrazine hydrate in 500 cc of ethanol was added, during a period of 5 hours, 92.5 grams of phenethylbromide (0.50 mol) in 150 cc of ethanol. Stirring and refluxing were continued for two hours. The ethanol was removed by distillation and the residue extracted repeatedly with ether. The ether was dried with potassium carbonate and the product base collected by distillation, BP 74°C/0.1 mm, yield 52.3 grams (77%). The base is reacted with sulfuric acid in propanol to give the sulfate.

brand name

Nardil (Parke-Davis).

Therapeutic Function

Psychostimulant

General Description

Phenelzine sulfate, 2-(phenylethyl)hydrazine sulfate(Nardil), is an effective antidepressant agent. A mechanismbasedinactivator, it irreversibly inactivates the enzyme orits cofactor, presumably after oxidation to the diazine,which can then break up into molecular nitrogen, a hydrogen atom, and a phenethyl free radical. The latter would bethe active species in irreversible inhibition.

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: wakefulness, blood pressure lowering, constipation, hepatitis, fibrous hepatitis. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. Used as a drug for the treatment of depression. When heated to decomposition it emits very toxic fumes of SOx and NOx.

Phenelzine Sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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Phenelzine Sulfate Suppliers

Canada 1 China 68 Germany 1 India 5 Italy 1 Switzerland 2 United Kingdom 2 United States 17 Global 97

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-61856358 15229202216
Fax: 029-88380327
Email: 1020@dideu.com
Country: China
ProdList: 10011
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
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Email: info@chemlin.com.cn
Country: China
ProdList: 19172
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

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View Lastest Price from Phenelzine Sulfate manufacturers

Dideu Industries Group Limited

Product: Phenelzine Sulfate 156-51-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-26

Career Henan Chemical Co

Product: Phenelzine (sulfate) 156-51-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-25

156-51-4, Phenelzine SulfateRelated Search:

Hydrazine sulfate Phenelzine Phenelzine Sulfate Methylhydrazine sulfate PHENELZINE-D5 SULFATE 2-PHENYLETHYLAMINE SULFATE 7-(4-FLUOROPHENYL)-1,2,3,4-TETRAHYDRO-2-(OXOPHENYLACETYL)-8-(4-PYRIDINYL)-PYRAZOLO[5,1-C][1,2,4]TRIAZINE SULFATE

Acid sulfate

alacine

alazin

alazine

beta-phenylethylhydrazinedihydrogensulfate

beta-phenylethylhydrazinehydrogensulphate

beta-phenylethylhydrazinesulfate

ep-411

estinerval

felazine

fenelzin

kalgan

mao-rem

nardelzine

p1531

phelazin

phenelzineacidsulfate

phenelzinebisulphate

phenelzinesulphate

phenethylhydrazinesulfate(1:1)

phenethylhydrazinesulphate

phenethyl-hydrazinsulfate(1:1)

(β-Phenylethyl)hydrazine dihydrogen sulfate

2-Phenethylhydrazine sulfate

NSC 170957

Phenelzine Bisulfate

Phenelzine Dihydrogen Sulfate

Phenelzine Hydrogen Sulfate

Phenethylhydrazine Sulfate

2-PHENYLETHYLHYDRAZINE SULFATE

(2-phenylethyl)-hydrazinsulfate(1:1)

1-hydrazino-2-phenylethanehydrogensulphate

2-phenylethylhydrazinedihydrogensulphate

2-phenylethylhydrazinehydrogensulphate

2-phenylethylhydrazinesulphate

PHENELZINE SULFATE

PHENELZINE SULFATE SALT

PHENYLETHYLHYDRAZINE SULFATE

phenline

phenylethylhydrazinedihydrogensulphate

phenylethylhydrazinesulphate

wl7

phenelzine hydrogen sulphate

3-PHENYLETHYLHYDRAZINESULPHATE

BETA-PHENYLETHYLHYDRAZINESULPHATE

HYDRAZINE,(2-PHENYLETHYL)-,SULPHATE

N-1544A

S-1544

Phenelzine Sulfate (200 mg)

(2-Phenylethyl)hydrazine dihydrogen sulfate

henelzine Sulfate

Phenelzine Sulfate USP/EP/BP

Phenelzine Sulfate (1517006)

inhibit,Inhibitor,Phenelzine sulfate,MAO,Monoamine Oxidase,Phenelzine

Phenelzine-d5 sulfate (phenyl-d5) in methanol

156-51-4

56-51-4

C8H14N2O4S