ChemicalBook > CAS DataBase List > Phenelzine Sulfate

Phenelzine Sulfate

Product Name
Phenelzine Sulfate
CAS No.
156-51-4
Chemical Name
Phenelzine Sulfate
Synonyms
wl7;p1531;ep-411;alazin;kalgan;S-1544;alazine;alacine;mao-rem;N-1544A
CBNumber
CB1719066
Molecular Formula
C8H14N2O4S
Formula Weight
234.27
MOL File
156-51-4.mol
More
Less

Phenelzine Sulfate Property

Melting point:
166.5-167.5 °C
storage temp. 
2-8°C
solubility 
Freely soluble in water; practically insoluble in ethanol (96%) and in ether .
form 
A solid
color 
White to off-white
Merck 
13,7300
CAS DataBase Reference
156-51-4
IARC
3 (Vol. 24, Sup 7) 1987
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
MV8750000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2928002500
Toxicity
LD50 orally in mice: 156 mg/kg (Gylys)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P6777
Product name
Phenelzine sulfate salt
Packaging
5g
Price
$407
Updated
2024/03/01
Sigma-Aldrich
Product number
1517006
Product name
Phenelzine sulfate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Sigma-Aldrich
Product number
BP1166
Product name
Phenelzine sulfate
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$231
Updated
2023/01/07
Cayman Chemical
Product number
23956
Product name
Phenelzine (sulfate)
Purity
≥98%
Packaging
250mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
23956
Product name
Phenelzine (sulfate)
Purity
≥98%
Packaging
500mg
Price
$120
Updated
2024/03/01
More
Less

Phenelzine Sulfate Chemical Properties,Usage,Production

Chemical Properties

A white powder or pearly platelets.

Originator

Nardil ,Parke Davis, US ,1959

Uses

antihistaminic

Uses

Phenelzine Sulfate is a hydrazine derivative that is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) and also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA levels. It is an antidep ressant and anxiolytic used in the treatment of major depressive disorder (MDD) as well as other neural disorders.

Definition

ChEBI: Phenelzine sulfate is an organic molecular entity.

Manufacturing Process

To a refluxing solution containing 147.5 grams of 85% hydrazine hydrate in 500 cc of ethanol was added, during a period of 5 hours, 92.5 grams of phenethylbromide (0.50 mol) in 150 cc of ethanol. Stirring and refluxing were continued for two hours. The ethanol was removed by distillation and the residue extracted repeatedly with ether. The ether was dried with potassium carbonate and the product base collected by distillation, BP 74°C/0.1 mm, yield 52.3 grams (77%). The base is reacted with sulfuric acid in propanol to give the sulfate.

brand name

Nardil (Parke-Davis).

Therapeutic Function

Psychostimulant

General Description

Phenelzine sulfate, 2-(phenylethyl)hydrazine sulfate(Nardil), is an effective antidepressant agent. A mechanismbasedinactivator, it irreversibly inactivates the enzyme orits cofactor, presumably after oxidation to the diazine,which can then break up into molecular nitrogen, a hydrogen atom, and a phenethyl free radical. The latter would bethe active species in irreversible inhibition.

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: wakefulness, blood pressure lowering, constipation, hepatitis, fibrous hepatitis. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. Used as a drug for the treatment of depression. When heated to decomposition it emits very toxic fumes of SOx and NOx.

Phenelzine Sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Phenelzine Sulfate Suppliers

Canada 1 China 68 Germany 1 India 5 Italy 1 Switzerland 2 United Kingdom 2 United States 17 Global 97
Shaanxi Dideu Medichem Co. Ltd
Tel
029-61856358 15229202216
Fax
029-88380327
Email
1020@dideu.com
Country
China
ProdList
10007
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2964
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Chengdu Novel Biomedical Co., Ltd.
Tel
028-85255396 18302801538
Fax
028-85255396
Email
cdnovell@163.com
Country
China
ProdList
2310
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Conier Chem & Pharma Limited
Tel
13368167990
Email
sales@conier.com
Country
China
ProdList
2830
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
10057
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
TOSUN PHARM
Tel
020-61855200 13326451905
Email
260366801@qq.com
Country
China
ProdList
7772
Advantage
58
Zhengzhou Ruike Biochemical Technology Co., Ltd.
Tel
18521304688
Email
421551521@qq.com
Country
China
ProdList
219
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22883
Advantage
58
HUNAN CHEMFISH SCIENTIFIC CO.,LTD
Tel
0731-85567275 18932438858
Fax
QQ:3554193828
Email
sales@chemfish.com
Country
China
ProdList
8356
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39894
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49374
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988968278
Fax
QQ：3283937693
Email
sales@ubiochem.com
Country
China
ProdList
4297
Advantage
58
Nanjing shengyilai Chemical Co., Ltd
Tel
19951936396
Email
3158688292@qq.com
Country
China
ProdList
4902
Advantage
58
Shanghai Luofa Biochemical Technology Co., Ltd.
Tel
021-51111890 15317326293
Email
sales@molnova.com
Country
China
ProdList
4195
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
Zhuhai Anzhe Biotechnology Co,Ltd.
Tel
13169972583
Email
513211116@qq.com
Country
China
ProdList
3006
Advantage
58
Yancheng Tongming Biotechnology Co., Ltd.
Tel
15195160625
Email
2863565288@qq.com
Country
China
ProdList
5192
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62163
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6753
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29794
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
15583
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel
13417589054 13417589054
Email
trendseenbio@gmail.com
Country
China
ProdList
9470
Advantage
58
Hubei Enxing Biotechnology Co., Ltd
Tel
16621771607
Email
exbio_tech@163.com
Country
China
ProdList
8210
Advantage
58
Auonsi (Shanghai) Biology Technology Co., Ltd.
Tel
400-1107768 15058188853
Fax
0571-88150696
Email
478133536@qq.com
Country
China
ProdList
8552
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12005
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
Advantage
58
SHANGHAI ZZBIO CO., LTD.
Tel
15102117276 19921389125
Email
tech@zzbioco.com
Country
China
ProdList
12065
Advantage
58
Cato Research Chemicals Inc.
Tel
13342851930
Email
3008394369@qq.com
Country
China
ProdList
15726
Advantage
58
Shaoguan Qicheng Biotechnology Co., Ltd
Tel
18122215013
Email
780229652@qq.com
Country
China
ProdList
1163
Advantage
58
Tel
4008-099-669
Email
23419001name@qq.com
Country
CHINA
ProdList
70071
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Email
sales@coreychem.com
Country
China
ProdList
29882
Advantage
58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Tel
+8613817748580
Fax
021-50175322
Email
cooperation@kean-chem.com
Country
China
ProdList
40066
Advantage
58
Dorne Chemical Technology co. LTD
Tel
+86-86-13583358881 +8618560316533
Email
Ethan@dornechem.com
Country
China
ProdList
3096
Advantage
58
More
Less

View Lastest Price from Phenelzine Sulfate manufacturers

Dideu Industries Group Limited
Product
Phenelzine Sulfate 156-51-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-26
Career Henan Chemical Co
Product
Phenelzine (sulfate) 156-51-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2018-12-25

156-51-4, Phenelzine SulfateRelated Search:

Hydrazine sulfate Phenelzine Phenelzine Sulfate Methylhydrazine sulfate PHENELZINE-D5 SULFATE 2-PHENYLETHYLAMINE SULFATE 7-(4-FLUOROPHENYL)-1,2,3,4-TETRAHYDRO-2-(OXOPHENYLACETYL)-8-(4-PYRIDINYL)-PYRAZOLO[5,1-C][1,2,4]TRIAZINE SULFATE

  • Acid sulfate
  • alacine
  • alazin
  • alazine
  • beta-phenylethylhydrazinedihydrogensulfate
  • beta-phenylethylhydrazinehydrogensulphate
  • beta-phenylethylhydrazinesulfate
  • ep-411
  • estinerval
  • felazine
  • fenelzin
  • kalgan
  • mao-rem
  • nardelzine
  • p1531
  • phelazin
  • phenelzineacidsulfate
  • phenelzinebisulphate
  • phenelzinesulphate
  • phenethylhydrazinesulfate(1:1)
  • phenethylhydrazinesulphate
  • phenethyl-hydrazinsulfate(1:1)
  • (β-Phenylethyl)hydrazine dihydrogen sulfate
  • 2-Phenethylhydrazine sulfate
  • NSC 170957
  • Phenelzine Bisulfate
  • Phenelzine Dihydrogen Sulfate
  • Phenelzine Hydrogen Sulfate
  • Phenethylhydrazine Sulfate
  • 2-PHENYLETHYLHYDRAZINE SULFATE
  • (2-phenylethyl)-hydrazinsulfate(1:1)
  • 1-hydrazino-2-phenylethanehydrogensulphate
  • 2-phenylethylhydrazinedihydrogensulphate
  • 2-phenylethylhydrazinehydrogensulphate
  • 2-phenylethylhydrazinesulphate
  • PHENELZINE SULFATE
  • PHENELZINE SULFATE SALT
  • PHENYLETHYLHYDRAZINE SULFATE
  • phenline
  • phenylethylhydrazinedihydrogensulphate
  • phenylethylhydrazinesulphate
  • wl7
  • phenelzine hydrogen sulphate
  • 3-PHENYLETHYLHYDRAZINESULPHATE
  • BETA-PHENYLETHYLHYDRAZINESULPHATE
  • HYDRAZINE,(2-PHENYLETHYL)-,SULPHATE
  • N-1544A
  • S-1544
  • Phenelzine Sulfate (200 mg)
  • (2-Phenylethyl)hydrazine dihydrogen sulfate
  • henelzine Sulfate
  • Phenelzine Sulfate USP/EP/BP
  • Phenelzine Sulfate (1517006)
  • inhibit,Inhibitor,Phenelzine sulfate,MAO,Monoamine Oxidase,Phenelzine
  • Phenelzine-d5 sulfate (phenyl-d5) in methanol
  • 156-51-4
  • 56-51-4
  • C8H14N2O4S