2,6-Dichloropurine

Product Name: 2,6-Dichloropurine
CAS No.: 5451-40-1
Chemical Name: 2,6-Dichloropurine
Synonyms: 2,6-DICHLORO-9H-PURINE;2,6-dichloro-7H-purine;2,6-dichloro-1H-purine;NSC 18395;Dichloropurine;6-Dichloropurine;2,6-DICHLOROPURINE;Cefepime Intermediate;2,6-Dichloropurine>2,6-Dichloropurine.97%
CBNumber: CB1720642
Molecular Formula: C5H2Cl2N4
Formula Weight: 189
MOL File: 5451-40-1.mol

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2,6-Dichloropurine Property

Melting point:: 185-195 °C (dec.) (lit.)
Boiling point:: 310.62°C (rough estimate)
Density: 1.7265 (rough estimate)
refractive index: 1.6300 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble
form: Crystalline Powder
pka: 5.22±0.20(Predicted)
color: White to yellow
Water Solubility: soluble
BRN: 9354
InChIKey: RMFWVOLULURGJI-UHFFFAOYSA-N
CAS DataBase Reference: 5451-40-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-22
Safety Statements: 22-24/25-37/39-26-36
RIDADR: UN2811
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D73103
Product name: 2,6-Dichloropurine
Purity: 97%
Packaging: 1g
Price: $17.48
Updated: 2024/03/01

Sigma-Aldrich

Product number: D73103
Product name: 2,6-Dichloropurine
Purity: 97%
Packaging: 5g
Price: $83.2
Updated: 2024/03/01

TCI Chemical

Product number: D2470
Product name: 2,6-Dichloropurine
Purity: >97.0%(HPLC)(T)
Packaging: 1g
Price: $24
Updated: 2024/03/01

TCI Chemical

Product number: D2470
Product name: 2,6-Dichloropurine
Purity: >97.0%(HPLC)(T)
Packaging: 5g
Price: $60
Updated: 2024/03/01

Alfa Aesar

Product number: B21289
Product name: 2,6-Dichloropurine, 97%
Packaging: 1g
Price: $76.65
Updated: 2024/03/01

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2,6-Dichloropurine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Suzuki-Miyaura cross-coupling between halopurines and arylboronic acids in water-acetonitrile.1

Uses

2,6-Dichloropurine is used in the synthesis of 2,6-diamino-substituted purine derivatives as potential cardiomyogenesis inducing agents.

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 404, 1958 DOI: 10.1021/ja01535a040

Purification Methods

It can be recrystallised from 150 parts of boiling H2O and dried at 100o to constant weight. It is soluble in EtOAc. The HgCl2 salt separates from EtOH solution. UV: max 275nm ( 8.9K) at pH 1; and 280nm ( 8.5K) at pH 11 [Elion & Hitchings J Am Chem Soc 78 3508 1956, Schaeffer & Thomas J Am Chem Soc 80 3738 1958, Beaman & Robins J Appl Chem (London) 12 432 1962, Montgomery J Am Chem Soc 78 1928 1956]. [Beilstein 26 III/IV 1747.]

2,6-Dichloropurine Preparation Products And Raw materials

Raw materials

Preparation Products

Cladribine 2,6-Dichloro-7-methylpurine

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2,6-Dichloropurine Suppliers

Americas 1 Belgium 1 Canada 3 China 444 Europe 3 France 1 Germany 7 India 16 Italy 1 Japan 3 Poland 1 Russia 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 20 United States 64 Global 572

Hunan Caiya Biological Technology Co., Ltd

Tel: 15580017485
Email: 2036676503@qq.com
Country: China
ProdList: 88
Advantage: 58

Nanjing Redwood Fine Chemical Co., Ltd.

Tel: 400-8464006 15805183379
Fax: 86-025-58905816
Email: zjp@redwood.com.cn
Country: China
ProdList: 645
Advantage: 60

LinkChem Co.,Ltd.

Tel: 021-021-58950110 13124863828
Fax: 021-20922272
Email: sales@linkchem.cn
Country: China
ProdList: 3000
Advantage: 58

Changzhou Jintan Maosheng Chemical Plant

Tel: 13382827140
Email: maoshengchem@126.com
Country: China
ProdList: 67
Advantage: 58

Suzhou Tianhong Medicine Chemical Technology Co.,Ltd.

Tel: 18949937116
Email: dongye.huaxue@126.com
Country: China
ProdList: 45
Advantage: 58

NANJING DORRA PHARMACEUTICAL TECHNOLOGY CO.,LTD.

Tel: 025-82232336 13815517432
Email: sales@dorrapharma.com
Country: China
ProdList: 33
Advantage: 58

Shanghai Tuolei Chemical Reagents Co., Ltd.

Tel: 86-021-50318510
Fax: 021-58650104
Country: China
ProdList: 69
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3576
Advantage: 66

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View Lastest Price from 2,6-Dichloropurine manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: 2,6-Dichloropurine 5451-40-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.91%
Supply Ability: 200000
Release date: 2024-04-19

Hebei Dangtong Import and export Co LTD

Product: 2,6-Dichloropurine 5451-40-1
Price: US $455.00-440.00/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 100Tons
Release date: 2023-03-03

airuikechemical co., ltd.

Product: 2,6-Dichloropurine 5451-40-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 20 tons
Release date: 2024-04-07

5451-40-1, 2,6-DichloropurineRelated Search:

Allopurinol 2',4'-Dichloroacetophenone 1,2-Dichloroethane Dichloroethane Adenine 2,6-DICHLOROPURINE-2'-DEOXYRIBOSIDE 2,6-Dichloropurine-9--D-riboside,2,6-Dichloropurine-9-b-D-riboside,2,6-DICHLOROPURINE RIBO,2,6-DICHLOROPURINE-9-BETA-D-RIBOSIDE,2,6-DICHLOROPURINE RIBOSIDE 2,6-dichloro-9-(1-methylethyl)-9H-purine 2,6,8-TRICHLOROPURINE 2,6-Dichloro-7-methylpurine DRB Cefepime Purine 2,6-dichloro-9-cyclopentyl-9H-purine 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE 2,6-DICHLORO-9-(2-DEOXY-3,5,DI-O-(4-METHYLBENZOYL-BETA-D-ERYTHROPENTOFURANOSYL)-9H-PURINE) 2,6-DICHLORO-9-METHYL-9H-PURINE 2,6,8-TRICHLORO-7-METHYLPURINE

2,6-DICHLORO-9H-PURINE

2,6-DICHLOROPURINE

2,6-Dichloropurine.97%

2,6-dichloro-1H-purine

1H-Purine, 2,6-dichloro-

Dichloropurine

Cefepime Intermediate

2,6-dichloro-7H-purine

9H-Purine, 2,6-dichloro-

6-Dichloropurine

NSC 18395

2,6-Dichloropurine&gt

2,6-Dichloropurine USP/EP/BP

5451-40-1

2001-2-5

5451-41-0

C5H2ClN4

HETERO CHLORIDE

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Purines

Building Blocks

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

Intermediates & Fine Chemicals

Pharmaceuticals

Nucleotides

Fused Ring Systems

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

PurinesHeterocyclic Building Blocks

Biochemistry

Nucleobases and their analogs

Nucleosides, Nucleotides & Related Reagents

Nucleic acids

Bases & Related Reagents

Pyridines, Pyrimidines, Purines and Pteredines

Halides

Purine

Nucleotides and Nucleosides

Purines

FINE Chemical & INTERMEDIATES

Starting Raw Materials & Intermediates

Heterocycles

5451-40-1