2,4,5-Trifluorobenzoic acid
- Product Name
- 2,4,5-Trifluorobenzoic acid
- CAS No.
- 446-17-3
- Chemical Name
- 2,4,5-Trifluorobenzoic acid
- Synonyms
- 2,4,5-Trilfuorobenzoic acid;2,4,5-TrifL;RARECHEM AL BO 0258;2,4,5-Trifluorobenzo;5-Trifluorobenzoic acid;2,4,5-tifluorobenzoicacid;2,4,5-TRIFLUOROBENZOIC ACID;Benzoic acid, 2,4,5-trifluoro-;2,4,5-Trifluorobenzoic acid 99%;2,4,5-Trifluorobenzoic acid ,99%
- CBNumber
- CB1742985
- Molecular Formula
- C7H3F3O2
- Formula Weight
- 176.09
- MOL File
- 446-17-3.mol
2,4,5-Trifluorobenzoic acid Property
- Melting point:
- 94-96 °C (lit.)
- Boiling point:
- 241.9±35.0 °C(Predicted)
- Density
- 1.4362 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 2.87±0.10(Predicted)
- color
- Off-White
- BRN
- 3257609
- InChIKey
- AKAMNXFLKYKFOJ-UHFFFAOYSA-N
- CAS DataBase Reference
- 446-17-3(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 2,4,5-trifluoro- (446-17-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 328154
- Product name
- 2,4,5-Trifluorobenzoic acid
- Purity
- 99%
- Packaging
- 5g
- Price
- $25.62
- Updated
- 2024/03/01
- Product number
- T1586
- Product name
- 2,4,5-Trifluorobenzoic Acid
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $54
- Updated
- 2024/03/01
- Product number
- T1586
- Product name
- 2,4,5-Trifluorobenzoic Acid
- Purity
- >97.0%(GC)(T)
- Packaging
- 25g
- Price
- $216
- Updated
- 2024/03/01
- Product number
- A14193
- Product name
- 2,4,5-Trifluorobenzoic acid, 98%
- Packaging
- 5g
- Price
- $94.65
- Updated
- 2024/03/01
- Product number
- A14193
- Product name
- 2,4,5-Trifluorobenzoic acid, 98%
- Packaging
- 1g
- Price
- $30.5
- Updated
- 2021/12/16
2,4,5-Trifluorobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
2,4,5-Trifluorobenzoic Acid is a useful synthetic intermediate. It can be used to synthesize quinolone antibacterial agnts.
Preparation
Synthesis of 2,4,5-trifluorobenzoic acid: Tetrachloroisophthalonitrile was used as the starting material, which was fluoridated, selectively reduced, and partially defluoridated to obtain 2,4,5-trifluoroisophthalonitrile. This compound was hydrolyzed to form 2,4,5-trifluoroisophthalic acid. Then, selective decarboxylation of 2,4,5-trifluorobenzoic acid was carried out to prepare 2,4,5-trifluorobenzoic acid.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 34, p. 168, 1991 DOI: 10.1021/jm00105a025
General Description
2,4,5-Trifluorobenzoic acid is an important quinolone antibacterial intermediate. It is used in the synthesis of Temafloxacin and liquid crystals, among others.
2,4,5-Trifluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2,4,5-Trifluorobenzoic acid Suppliers
View Lastest Price from 2,4,5-Trifluorobenzoic acid manufacturers
- Product
- 2,4,5-trifluorobenzoic acid 446-17-3
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 446-17-3
- Release date
- 2019-12-24
- Product
- 2,4,5-Trifluorobenzoic acid 446-17-3
- Price
- US $35.00-1.10/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-19
- Product
- 2,4,5-Trifluorobenzoic acid 446-17-3
- Price
- US $70.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-04-20