1-METHYLPIPERIDINE-4-CARBOXAMIDE

Product Name: 1-METHYLPIPERIDINE-4-CARBOXAMIDE
CAS No.: 62718-28-9
Chemical Name: 1-METHYLPIPERIDINE-4-CARBOXAMIDE
Synonyms: 1-methylisonipecotamide;1-METHYLPIPERIDINE-4-CARBOXAMIDE;N-METHYLPIPERIDINE-4-CARBOXAMIDE;1-Methyl-4-PiperidinecarboxaMide;4-Piperidinecarboxamide, 1-methyl-;4-Piperidinecarboxamide,1-methyl-(9CI)
CBNumber: CB1744015
Molecular Formula: C7H14N2O
Formula Weight: 142.2
MOL File: 62718-28-9.mol

More

Less

1-METHYLPIPERIDINE-4-CARBOXAMIDE Property

storage temp.: Sealed in dry,Room Temperature
Appearance: White to off-white Solid

More

Less

Safety

HazardClass: IRRITANT

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: M647330
Product name: 1-methylpiperidine-4-carboxamide
Packaging: 100mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: J96572
Product name: 1-Methylpiperidine-4-carboxamide
Packaging: 250mg
Price: $86
Updated: 2021/12/16

AK Scientific

Product number: J96572
Product name: 1-Methylpiperidine-4-carboxamide
Packaging: 100mg
Price: $43
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0006864
Product name: 1-METHYLPIPERIDINE-4-CARBOXAMIDE
Purity: 95.00%
Packaging: 0.5G
Price: $682
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0006864
Product name: 1-METHYLPIPERIDINE-4-CARBOXAMIDE
Purity: 95.00%
Packaging: 1G
Price: $750.75
Updated: 2021/12/16

More

Less

1-METHYLPIPERIDINE-4-CARBOXAMIDE Chemical Properties,Usage,Production

Synthesis

39546-32-2

50-00-0

62718-28-9

Piperidine-4-carboxamide (10 g, 78 mmol) was dissolved in distilled water (100 mL) and 37% aqueous formaldehyde solution (7.6 mL, equivalent to 2.81 g HCHO, 93.6 mmol) was added. Under argon protection, wet 10% Pd/C catalyst (8 spatula scoops) was added and the mixture was hydrogenated for 43 h at 25 °C and 50 psi hydrogen pressure. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the catalyst was washed with water and methanol. The filtrates were combined and evaporated to dryness. The residue was purified by silica gel column chromatography (60 x 5 cm) to afford 1-methylpiperidine-4-carboxamide (7.15 g, 64% yield) using 8%-10%-20% (10% concentrated ammonia in methanol solution)-dichloromethane as eluent. The product characterization data were as follows: FABMS: m/z 143.1 (MH+); HRFABMS: m/z 143.1184 (MH+), calculated value C7H15N2O: m/z 143.1184; 1H NMR (d6-DMSO) δ 1.50-1.57 (4H, m, CH2), 1.76-1.94 (4H, m. CH2), 2.10 (3H, s, -NCH3), 2.72 (1H, m, CH), 6.68-7.18 (2H, m, CONH2); 13C NMR (d6-DMSO) δ 41.2 (CH3), 28.5, 28.5, 54.9, 54.9 (CH2), 46.2 (CH), 176.7 (C).

References

[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 7, p. 1116 - 1119
[2] Patent: WO2004/22561, 2004, A1. Location in patent: Page 110
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 24, p. 7520 - 7534
[4] Helvetica Chimica Acta, 1954, vol. 37, p. 1672,1676

1-METHYLPIPERIDINE-4-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-METHYLPIPERIDINE-4-CARBOXAMIDE Suppliers

Canada 1 China 44 Europe 1 India 3 United Kingdom 3 United States 5 Global 57

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Dalian lichuang Chemical Co., Ltd

Tel: 0411-0411-00000000 13644282108
Fax: -
Email: 3500508746@qq.com
Country: China
ProdList: 2896
Advantage: 55

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8595
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

62718-28-9, 1-METHYLPIPERIDINE-4-CARBOXAMIDERelated Search:

SPIPERONE SPIROXATRINE FLUSPIRILENE N-Methylpiperidine 8-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE HYDROCHLORIDE 1-(3-NITROPYRIDIN-2-YL)PIPERIDINE-4-CARBOXAMIDE 1-benzyl-4-(ethylamino)piperidine-4-carboxamide 8-acetyl-3-dodecyl-7,7,9,9-tetramethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione N-METHYL-8-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-1-PHENYL-1,3,8-TRIAZASPIRO-[4.5]DECAN-4-ONE HYDROCHLORIDE N-(([(2,6-DICHLOROBENZYL)OXY]IMINO)METHYL)-1-(2-PYRIMIDINYL)-4-PIPERIDINECARBOXAMIDE N-(P-ISOTHIOCYANATOPHENETHYL)SPIPERONE HYDROCHLORIDE N-(([(4-CHLOROBENZYL)OXY]IMINO)METHYL)-1-(2-PYRIMIDINYL)-4-PIPERIDINECARBOXAMIDE N-[(DIMETHYLAMINO)METHYLENE]-1-(2-PYRIMIDINYL)-4-PIPERIDINECARBOXAMIDE 1-(2-cyano-3-fluorophenyl)piperidine-4-carboxamide 1-[5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-YL]-4-PIPERIDINECARBOXAMIDE 1-(2-PYRIMIDINYL)-4-PIPERIDINECARBOXAMIDE N-(4-CHLOROPHENYL)-1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4-PIPERIDINECARBOXAMIDE (1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4-PIPERIDINYL)[4-(4-METHOXYPHENYL)PIPERAZINO]METHANONE

N-METHYLPIPERIDINE-4-CARBOXAMIDE

1-METHYLPIPERIDINE-4-CARBOXAMIDE

4-Piperidinecarboxamide,1-methyl-(9CI)

1-Methyl-4-PiperidinecarboxaMide

1-methylisonipecotamide

4-Piperidinecarboxamide, 1-methyl-

62718-28-9

AMIDE

Pyrans, Piperidines &Piperazines

Pyrans, Piperidines & Piperazines