4-(4'-Bromophenyl)piperidine
- Product Name
- 4-(4'-Bromophenyl)piperidine
- CAS No.
- 80980-89-8
- Chemical Name
- 4-(4'-Bromophenyl)piperidine
- Synonyms
- 4-(4-BROMOPHENYL)PIPERIDINE;4-(4'-Bromophenyl)piperidine;Piperidine, 4-(4-bromophenyl)-;4-(4′-Bromophenyl)piperidine, CAS 80980-89-8
- CBNumber
- CB1748699
- Molecular Formula
- C11H14BrN
- Formula Weight
- 240.14
- MOL File
- 80980-89-8.mol
4-(4'-Bromophenyl)piperidine Property
- Melting point:
- 144-146 °C
- Boiling point:
- 307.6±42.0 °C(Predicted)
- Density
- 1.313±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- solid
- pka
- 10.14±0.10(Predicted)
- color
- Pale yellow
- InChI
- InChI=1S/C11H14BrN/c12-11-3-1-9(2-4-11)10-5-7-13-8-6-10/h1-4,10,13H,5-8H2
- InChIKey
- ZKABWLFDCJKQRE-UHFFFAOYSA-N
- SMILES
- N1CCC(C2=CC=C(Br)C=C2)CC1
- CAS DataBase Reference
- 80980-89-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-52
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 037289
- Product name
- 4-(4-Bromophenyl)piperidine
- Packaging
- 500mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- FB150418
- Product name
- 4-(4'-Bromophenyl)piperidine
- Packaging
- 50mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- 3H31-9-47
- Product name
- 4-(4-Bromophenyl)piperidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- FB150418
- Product name
- 4-(4'-Bromophenyl)piperidine
- Packaging
- 100mg
- Price
- $103
- Updated
- 2021/12/16
- Product number
- FB150418
- Product name
- 4-(4'-Bromophenyl)piperidine
- Packaging
- 250mg
- Price
- $205
- Updated
- 2021/12/16
4-(4'-Bromophenyl)piperidine Chemical Properties,Usage,Production
Synthesis
91347-99-8
80980-89-8
General procedure for the synthesis of 4-(4-bromophenyl)piperidine from 4-(4-bromophenyl)-1,2,3,6-tetrahydropyridine: to a solution of 4-(4-bromophenyl)-1,2,3,6-tetrahydropyridine (0.90 g, 3.78 mmol) in anhydrous methanol (20 mL) and triethylamine (2 mL), the Rh/C catalyst (0.060 g, J. Bishop & Co. Platinum). The reaction mixture was placed in a hydrogen atmosphere (100 psi) and stirred at room temperature for 24 hours. Upon completion of the reaction, the mixture was filtered through a Celite?(Sigma Aldrich, St. Louis, MO) filter cake and the filtrate was concentrated to afford 4-(4-bromophenyl)piperidine as a white solid (0.91 g, 98% yield). The product was confirmed by 1H NMR (400 MHz, MeOD): δ 1.55-1.59 (2H, m), 1.61-1.70 (2H, m), 2.55-2.56 (1H, m), 2.64-2.70 (2H, m), 3.09-3.06 (2H, m), 7.13 (2H, J = 8.0 Hz, d), 7.31 ( 2H, J = 8.0 Hz, d).13C NMR (100 MHz, MeOD): δ 32.7, 41.4, 45.6, 119.4, 126.4, 128.2, 128.5, 131.2, 145.3. m/z of mass spectrum (ESI-MS): 241 [M+H]+.
References
[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 13, p. 6149 - 6168
[2] Patent: WO2017/53769, 2017, A1. Location in patent: Paragraph 0117; 0118
4-(4'-Bromophenyl)piperidine Preparation Products And Raw materials
Raw materials
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View Lastest Price from 4-(4'-Bromophenyl)piperidine manufacturers
- Product
- 4-(4"-Bromophenyl)piperidine 80980-89-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 4-(4"-Bromophenyl)piperidine 80980-89-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 4-(4'-Bromophenyl)piperidine 80980-89-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2018-08-06