4-Nitrophenyl isocyanate
- Product Name
- 4-Nitrophenyl isocyanate
- CAS No.
- 100-28-7
- Chemical Name
- 4-Nitrophenyl isocyanate
- Synonyms
- ai3-28253;4-Nitrophenyl;TIMTEC-BB SBB006628;4-Nitrophenyl isocya;4-Nitrophenylcarbimide;4-NITROPHENYL ISOCYANATE;P-NITROPHENYL ISOCYANATE;4-Isocyanatonitrobenzene;PARA-NITROPHENYLISOCYANATE;1-isocyanato-4-nitro-benzen
- CBNumber
- CB1757004
- Molecular Formula
- C7H4N2O3
- Formula Weight
- 164.12
- MOL File
- 100-28-7.mol
4-Nitrophenyl isocyanate Property
- Melting point:
- 56-59 °C(lit.)
- Boiling point:
- 137-138 °C11 mm Hg(lit.)
- Density
- 1.5018 (rough estimate)
- refractive index
- 1.5300 (estimate)
- Flash point:
- >110°C
- storage temp.
- 2-8°C
- solubility
- soluble in Benzene,Toluene
- form
- Crystalline Solid
- color
- Yellow
- Water Solubility
- Insoluble in water.
- Sensitive
- Moisture Sensitive
- BRN
- 389516
- CAS DataBase Reference
- 100-28-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, 1-isocyanato-4-nitro-(100-28-7)
- EPA Substance Registry System
- p-Nitrophenyl isocyanate (100-28-7)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38-42
- Safety Statements
- 22-26-36/37/39-45
- RIDADR
- 2206
- WGK Germany
- 3
- RTECS
- DA3692500
- F
- 10-19-21
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29291090
- Toxicity
- LD50 orl-rat: 1600 mg/kg NTIS** OTS0528342
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 269425
- Product name
- 4-Nitrophenyl isocyanate
- Purity
- 97%
- Packaging
- 5g
- Price
- $47.2
- Updated
- 2023/06/20
- Product number
- 269425
- Product name
- 4-Nitrophenyl isocyanate
- Purity
- 97%
- Packaging
- 25g
- Price
- $183
- Updated
- 2023/06/20
- Product number
- I0129
- Product name
- 4-Nitrophenyl Isocyanate (contains varying amounts of polymers)
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $108
- Updated
- 2023/06/20
- Product number
- I0129
- Product name
- 4-Nitrophenyl Isocyanate (contains varying amounts of polymers)
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $313
- Updated
- 2023/06/20
- Product number
- A11194
- Product name
- 4-Nitrophenyl isocyanate, 97%
- Packaging
- 5g
- Price
- $38.6
- Updated
- 2023/06/20
4-Nitrophenyl isocyanate Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline solid
Uses
4-Nitrophenyl isocyanate is used as pharmaceutical intermediates. 4-Nitrophenyl isocyanate was used in the synthesis of 2-(5-methyl-3,4-diphenyl-1H-pyrrole-2-carbonyl)-N-(4-nitrophenyl)hydrazinecarboxamide.
Safety Profile
A poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.
Purification Methods
Distil the isocyanate in a vacuum, and/or recrystallise it from pet ether (b 28-38o), *C6H6/pet ether (m 58o) or CCl4 (m 56-57o). [Beilstein 12 H 725, 12 III 1630.]