L-701,324

ChemicalBook > CAS DataBase List > L-701,324

Product Name: L-701,324
CAS No.: 142326-59-8
Chemical Name: L-701,324
Synonyms: L-701;CS-2045;L-701,324;L-701,304;L-701324, 10 mM in DMSO;L 701324, glycine site NMDA receptor antagonist;7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(H)-quinolinone;7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE;7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one;7-chloro-1-(4-hydroxy-3-phenoxyphenyl)quinolin-2(1H)-one
CBNumber: CB1757589
Molecular Formula: C21H14ClNO3
Formula Weight: 363.79
MOL File: 142326-59-8.mol

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L-701,324 Property

Melting point:: 308 °C
Boiling point:: 584.7±50.0 °C(Predicted)
Density: 1.389±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO: soluble36.4mg/mL
form: solid
pka: 4.50±1.00(Predicted)
color: White to off-white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 0907
Product name: L-701,324
Purity: ≥99%(HPLC)
Packaging: 10
Price: $156
Updated: 2021/12/16

Tocris

Product number: 0907
Product name: L-701,324
Purity: ≥99%(HPLC)
Packaging: 50
Price: $645
Updated: 2021/12/16

Usbiological

Product number: 453163
Product name: L-701,324
Packaging: 10mg
Price: $403
Updated: 2021/12/16

TRC

Product number: L009510
Product name: L-701,324
Packaging: 10mg
Price: $115
Updated: 2021/12/16

ChemScene

Product number: CS-4968
Product name: L-701324
Purity: 99.99%
Packaging: 10mg
Price: $132
Updated: 2021/12/16

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L-701,324 Chemical Properties,Usage,Production

Uses

L-701,324 is a potential anticonvulsant with high selectivity and affinity for the NMDA receptor glycine site. NMDA receptors are expressed by small-cell lung cancer and are potential targets for effective treatment.

Definition

ChEBI: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one is a member of quinolines.

Biological Activity

An orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor.

storage

Store at RT

L-701,324 Preparation Products And Raw materials

Raw materials

Preparation Products

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L-701,324 Suppliers

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View Lastest Price from L-701,324 manufacturers

Career Henan Chemical Co

Product: L-701,324 142326-59-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2020-01-13

142326-59-8, L-701,324Related Search:

Phenol L-701,324 TRANS-4-CHLOROSTILBENE 7-Chloro-2-hydroxyquinoline

7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE

7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE

7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(H)-quinolinone

L-701,304

7-chloro-1-(4-hydroxy-3-phenoxyphenyl)quinolin-2(1H)-one

CS-2045

7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one

L-701

L-701,324

2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-

L-701324,Ionotropic glutamate receptors,inhibit,Inhibitor,tail suspension test,chronic unpredictable mild stress,antidepressant,forced swim test,iGluR,glycine B binding site,brain membranes,L 701324

7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1,2-dihydroquinolin-2-one

L 701324, glycine site NMDA receptor antagonist

L-701324, 10 mM in DMSO

142326-59-8

C21H14CINO3

Ionotropic Glutamate Receptor Modulators

Ion Channels

Ligand-Gated Ion Channels

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Inhibitors