ChemicalBook > CAS DataBase List > L-701,324

L-701,324

Product Name
L-701,324
CAS No.
142326-59-8
Chemical Name
L-701,324
Synonyms
L-701;CS-2045;L-701,324;L-701,304;7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(H)-quinolinone;7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE;7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one;7-chloro-1-(4-hydroxy-3-phenoxyphenyl)quinolin-2(1H)-one;7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE;2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-
CBNumber
CB1757589
Molecular Formula
C21H14ClNO3
Formula Weight
363.79
MOL File
142326-59-8.mol
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L-701,324 Property

Melting point:
308 °C
Boiling point:
584.7±50.0 °C(Predicted)
Density 
1.389±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: soluble36.4mg/mL
form 
solid
pka
4.50±1.00(Predicted)
color 
White to off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
0907
Product name
L-701,324
Purity
≥99%(HPLC)
Packaging
10
Price
$156
Updated
2021/12/16
Tocris
Product number
0907
Product name
L-701,324
Purity
≥99%(HPLC)
Packaging
50
Price
$645
Updated
2021/12/16
Usbiological
Product number
453163
Product name
L-701,324
Packaging
10mg
Price
$403
Updated
2021/12/16
TRC
Product number
L009510
Product name
L-701,324
Packaging
10mg
Price
$115
Updated
2021/12/16
ChemScene
Product number
CS-4968
Product name
L-701324
Purity
99.99%
Packaging
10mg
Price
$132
Updated
2021/12/16
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L-701,324 Chemical Properties,Usage,Production

Uses

L-701,324 is a potential anticonvulsant with high selectivity and affinity for the NMDA receptor glycine site. NMDA receptors are expressed by small-cell lung cancer and are potential targets for effective treatment.

Definition

ChEBI: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one is a member of quinolines.

Biological Activity

An orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor.

storage

Store at RT

L-701,324 Preparation Products And Raw materials

Raw materials

Preparation Products

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L-701,324 Suppliers

China 56 Germany 1 Japan 1 South Korea 1 Switzerland 1 United Kingdom 4 United States 16 Global 80
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from L-701,324 manufacturers

Career Henan Chemical Co
Product
L-701,324 142326-59-8
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2020-01-13

142326-59-8, L-701,324Related Search:

Phenol L-701,324 TRANS-4-CHLOROSTILBENE 7-Chloro-2-hydroxyquinoline

  • 7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE
  • 7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE
  • 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(H)-quinolinone
  • L-701,304
  • 7-chloro-1-(4-hydroxy-3-phenoxyphenyl)quinolin-2(1H)-one
  • CS-2045
  • 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one
  • L-701
  • L-701,324
  • 2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-
  • L-701324,Ionotropic glutamate receptors,inhibit,Inhibitor,tail suspension test,chronic unpredictable mild stress,antidepressant,forced swim test,iGluR,glycine B binding site,brain membranes,L 701324
  • 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1,2-dihydroquinolin-2-one
  • 142326-59-8
  • C21H14CINO3
  • Ionotropic Glutamate Receptor Modulators
  • Ion Channels
  • Ligand-Gated Ion Channels
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Inhibitors