ChemicalBook > CAS DataBase List > 4-HYDROXYPHENOXYACETIC ACID

4-HYDROXYPHENOXYACETIC ACID

Product Name: 4-HYDROXYPHENOXYACETIC ACID
CAS No.: 1878-84-8
Chemical Name: 4-HYDROXYPHENOXYACETIC ACID
Synonyms: 4-HYDROXYPHENOXYACETIC ACID;(4-hydroxyphenoxy)-aceticaci;2-(4-hydroxyphenoxy)aceticaci;(P-HYDROXYPHENOXY)ACETIC ACID;2-(4-Hydroxyphenoxy)acetic acid;4-Hydroxyphenoxyacetic acid, 98+%;Acetic acid, 2-(4-hydroxyphenoxy)-;2-(4-Hydroxyphenoxy)ethanoic acid, 4-(Carboxymethoxy)phenol
CBNumber: CB1760189
Molecular Formula: C8H8O4
Formula Weight: 168.15
MOL File: 1878-84-8.mol

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4-HYDROXYPHENOXYACETIC ACID Property

Melting point:: 154-157 °C (lit.)
Boiling point:: 372.6±17.0 °C(Predicted)
Density: 1.367±0.06 g/cm3(Predicted)
storage temp.: RT, stored under nitrogen
solubility: soluble in Methanol
form: Fine Crystalline Powder
pka: 3.27±0.10(Predicted)
color: Off-white to beige
BRN: 1952779
LogP: 0.650
CAS DataBase Reference: 1878-84-8(CAS DataBase Reference)
EPA Substance Registry System: Acetic acid, (4-hydroxyphenoxy)- (1878-84-8)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
TSCA: Yes
HS Code: 29189990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 439398
Product name: (4-Hydroxyphenoxy)acetic acid
Purity: 98%
Packaging: 5g
Price: $51.4
Updated: 2025/07/31

TCI Chemical

Product number: H0992
Product name: (4-Hydroxyphenoxy)acetic Acid
Purity: >99.0%(T)
Packaging: 5g
Price: $80
Updated: 2025/07/31

TCI Chemical

Product number: H0992
Product name: (4-Hydroxyphenoxy)acetic Acid
Purity: >99.0%(T)
Packaging: 25g
Price: $260
Updated: 2025/07/31

TRC

Product number: H801505
Product name: 2-(4-Hydroxyphenoxy)aceticAcid
Packaging: 0.25g
Price: $50
Updated: 2021/12/16

TRC

Product number: H801505
Product name: 2-(4-Hydroxyphenoxy)aceticAcid
Packaging: 5g
Price: $150
Updated: 2021/12/16

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4-HYDROXYPHENOXYACETIC ACID Chemical Properties,Usage,Production

Chemical Properties

off-white to beige fine crystalline powder

Uses

2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.

Definition

ChEBI: 4-Hydroxypheoxyacetate is a monocarboxylic acid.

General Description

(4-Hydroxyphenoxy)acetic acid along with formaldehyde ammonium salt forms a polyaromatic anionic compound RG-13577. RG-13577 mimics the synthetic heparin and specifically binds to the vascular smooth muscle cells (SMCs) and inhibits their proliferative growth. In the molecules of (4-hydroxyphenoxy)acetic acid, the carboxyl groups are held together by R₂²(8) hydrogen bonds.

4-HYDROXYPHENOXYACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXYPHENOXYACETIC ACID Suppliers

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1878-84-8, 4-HYDROXYPHENOXYACETIC ACIDRelated Search:

4-BENZYLOXYPHENOXYACETIC ACID Quizalofop-p-ethyl Trolox Diclofop 4-HYDROXYPHENOXYACETIC ACID 4-Methoxyphenoxyacetic acid Diclofop-methyl HYDROQUINONE-O,O'-DIACETIC ACID Haloxyfop-etotyl 4-O-(Carboxymethyl)rifamycin 4-(TRIFLUOROMETHOXY)PHENOXYACETIC ACID 2-HYDROXYPHENOXYACETIC ACID,2-Hydroxyphenoxyacetic acid, 98+% Phenoxyacetic acid 4-ACETOXYPHENOXYACETIC ACID 2-(4-HYDROXYPHENOXY)PROPIONIC ACID 3,5-DIBROMO-4-HYDROXYPHENOXYACETIC ACID DICLOFOP METHYL, 5-HYDROXY DL-2-[4-(TRIFLUOROMETHOXY)PHENOXY]PROPIONIC ACID

4-HYDROXYPHENOXYACETIC ACID

2-(4-Hydroxyphenoxy)acetic acid

2-(4-Hydroxyphenoxy)ethanoic acid, 4-(Carboxymethoxy)phenol

(P-HYDROXYPHENOXY)ACETIC ACID

(4-hydroxyphenoxy)-aceticaci

4-Hydroxyphenoxyacetic acid, 98+%

Acetic acid, 2-(4-hydroxyphenoxy)-

2-(4-hydroxyphenoxy)aceticaci

1878-84-8

HOC6H4OCH2CO2H

Building Blocks

Carbonyl Compounds

Carboxylic Acids

Organic Building Blocks

Phenoxyacetic Acids and Alcohols (substituted)

Carbonyl Compounds

Carboxylic Acids