ChemicalBook > CAS DataBase List > 4-HYDROXYPHENOXYACETIC ACID

4-HYDROXYPHENOXYACETIC ACID

Product Name
4-HYDROXYPHENOXYACETIC ACID
CAS No.
1878-84-8
Chemical Name
4-HYDROXYPHENOXYACETIC ACID
Synonyms
4-HYDROXYPHENOXYACETIC ACID;(4-hydroxyphenoxy)-aceticaci;2-(4-hydroxyphenoxy)aceticaci;(P-HYDROXYPHENOXY)ACETIC ACID;2-(4-Hydroxyphenoxy)acetic acid;4-Hydroxyphenoxyacetic acid, 98+%;Acetic acid, 2-(4-hydroxyphenoxy)-;2-(4-Hydroxyphenoxy)ethanoic acid, 4-(Carboxymethoxy)phenol
CBNumber
CB1760189
Molecular Formula
C8H8O4
Formula Weight
168.15
MOL File
1878-84-8.mol
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4-HYDROXYPHENOXYACETIC ACID Property

Melting point:
154-157 °C (lit.)
Boiling point:
372.6±17.0 °C(Predicted)
Density 
1.367±0.06 g/cm3(Predicted)
solubility 
soluble in Methanol
form 
Fine Crystalline Powder
pka
3.27±0.10(Predicted)
color 
Off-white to beige
BRN 
1952779
LogP
0.650
CAS DataBase Reference
1878-84-8(CAS DataBase Reference)
EPA Substance Registry System
Acetic acid, (4-hydroxyphenoxy)- (1878-84-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
TSCA 
Yes
HS Code 
29189990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
439398
Product name
(4-Hydroxyphenoxy)acetic acid
Purity
98%
Packaging
5g
Price
$49.9
Updated
2024/03/01
TCI Chemical
Product number
H0992
Product name
(4-Hydroxyphenoxy)acetic Acid
Purity
>99.0%(T)
Packaging
5g
Price
$81
Updated
2024/03/01
TCI Chemical
Product number
H0992
Product name
(4-Hydroxyphenoxy)acetic Acid
Purity
>99.0%(T)
Packaging
25g
Price
$262
Updated
2024/03/01
Alfa Aesar
Product number
A12940
Product name
4-Hydroxyphenoxyacetic acid, 98+%
Packaging
5g
Price
$62.65
Updated
2024/03/01
Alfa Aesar
Product number
A12940
Product name
4-Hydroxyphenoxyacetic acid, 98+%
Packaging
25g
Price
$216.65
Updated
2024/03/01
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4-HYDROXYPHENOXYACETIC ACID Chemical Properties,Usage,Production

Chemical Properties

off-white to beige fine crystalline powder

Uses

2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.

Definition

ChEBI: 4-Hydroxypheoxyacetate is a monocarboxylic acid.

General Description

(4-Hydroxyphenoxy)acetic acid along with formaldehyde ammonium salt forms a polyaromatic anionic compound RG-13577. RG-13577 mimics the synthetic heparin and specifically binds to the vascular smooth muscle cells (SMCs) and inhibits their proliferative growth. In the molecules of (4-hydroxyphenoxy)acetic acid, the carboxyl groups are held together by R22(8) hydrogen bonds.

4-HYDROXYPHENOXYACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXYPHENOXYACETIC ACID Suppliers

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1878-84-8, 4-HYDROXYPHENOXYACETIC ACIDRelated Search:

4-BENZYLOXYPHENOXYACETIC ACID Quizalofop-p-ethyl Trolox Diclofop 4-HYDROXYPHENOXYACETIC ACID 4-Methoxyphenoxyacetic acid Diclofop-methyl HYDROQUINONE-O,O'-DIACETIC ACID Haloxyfop-etotyl 4-O-(Carboxymethyl)rifamycin 4-(TRIFLUOROMETHOXY)PHENOXYACETIC ACID 2-HYDROXYPHENOXYACETIC ACID,2-Hydroxyphenoxyacetic acid, 98+% Phenoxyacetic acid 4-ACETOXYPHENOXYACETIC ACID 2-(4-HYDROXYPHENOXY)PROPIONIC ACID 3,5-DIBROMO-4-HYDROXYPHENOXYACETIC ACID DICLOFOP METHYL, 5-HYDROXY DL-2-[4-(TRIFLUOROMETHOXY)PHENOXY]PROPIONIC ACID

  • 4-HYDROXYPHENOXYACETIC ACID
  • 2-(4-Hydroxyphenoxy)acetic acid
  • 2-(4-Hydroxyphenoxy)ethanoic acid, 4-(Carboxymethoxy)phenol
  • (P-HYDROXYPHENOXY)ACETIC ACID
  • (4-hydroxyphenoxy)-aceticaci
  • 4-Hydroxyphenoxyacetic acid, 98+%
  • Acetic acid, 2-(4-hydroxyphenoxy)-
  • 2-(4-hydroxyphenoxy)aceticaci
  • 1878-84-8
  • HOC6H4OCH2CO2H
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • C8
  • Organic Building Blocks
  • Phenoxyacetic Acids and Alcohols (substituted)
  • Carbonyl Compounds
  • Carboxylic Acids
  • C8