6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE
- Product Name
- 6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE
- CAS No.
- 120-15-0
- Chemical Name
- 6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE
- Synonyms
- Thallin;AKOS BB-9796;TIMTEC-BB SBB002326;SALOR-INT L308625-1EA;Debrisoquine Impurity 11;6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE;Quinoline l,2,3,4-tetrahydro-6-methoxy;Quinoline, 1,2,3,4-tetrahydro-6-methoxy-;6-Methoxy-1,2,3,4-tetrahydroquinoline 99%;methyl 1,2,3,4-tetrahydro-6-quinolyl ether
- CBNumber
- CB1764400
- Molecular Formula
- C10H13NO
- Formula Weight
- 163.22
- MOL File
- 120-15-0.mol
6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE Property
- Melting point:
- 37-41 °C (lit.)
- Boiling point:
- 290.31°C (rough estimate)
- Density
- 1.0508 (rough estimate)
- refractive index
- 1.5718 (estimate)
- RTECS
- VC2940000
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 5.95±0.20(Predicted)
- CAS DataBase Reference
- 120-15-0(CAS DataBase Reference)
- EPA Substance Registry System
- Quinoline, 1,2,3,4-tetrahydro-6-methoxy- (120-15-0)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M268808
- Product name
- 6-Methoxy-1,2,3,4-tetrahydroquinoline
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- OR964112
- Product name
- 6-Methoxy-1,2,3,4-tetrahydroquinoline
- Purity
- 95%
- Packaging
- 1g
- Price
- $124
- Updated
- 2021/12/16
- Product number
- P000626393
- Product name
- 6-Methoxy-1,2,3,4-tetrahydroquinoline
- Purity
- 95+%
- Packaging
- 5g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- J98188
- Product name
- 6-Methoxy-1,2,3,4-tetrahydroquinoline
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- P000626393
- Product name
- 6-Methoxy-1,2,3,4-tetrahydroquinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $44
- Updated
- 2021/12/16
6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE Chemical Properties,Usage,Production
Uses
1,2,3,4-Tetrahydro-6-methoxyquinoline is used as chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.
Synthesis
5263-87-6
120-15-0
GENERAL STEPS: 6-methoxyquinoline (1a; 65 mg, 0.5 mmol), Cu(OAc)2 (4.5 mg, 0.025 mmol), B2(OH)4 (135 mg, 1.5 mmol) and acetonitrile (2.0 mL) were added to a 20 mL Schlenk tube. The reaction mixture was stirred at 40 °C for 8 h. The progress of the reaction was monitored by TLC until the reaction was completed. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. Water (10 mL) was added to the concentrated mixture, followed by extraction with ethyl acetate (3 x 10 mL). The organic phases were combined, dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure. The residue was purified by column chromatography using petroleum ether/ethyl acetate (8:1) as eluent to afford the target product 6-methoxy-1,2,3,4-tetrahydroquinoline (2a: 65 mg, 98% yield) as a brown liquid.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 13, p. 3415 - 3418
[2] Advanced Synthesis and Catalysis, 2017, vol. 359, # 4, p. 677 - 686
[3] Advanced Synthesis and Catalysis, 2017, vol. 359, # 6, p. 933 - 940
[4] Chemistry - A European Journal, 2016, vol. 22, # 48, p. 17151 - 17155
[5] ChemCatChem, 2017, vol. 9, # 13, p. 2496 - 2505
6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE Suppliers
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 031185291771 13832391721
- Fax
- 0311-67305698
- yaofeng2005@163.com
- Country
- China
- ProdList
- 978
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 010-56330744 18310155299
- Fax
- 010-56330744
- sales@labter.com.cn
- Country
- China
- ProdList
- 20000
- Advantage
- 55
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
View Lastest Price from 6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE manufacturers
- Product
- 6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE 120-15-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Kg/T
- Release date
- 2019-12-19