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4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE

Product Name
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
CAS No.
14279-91-5
Chemical Name
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
Synonyms
BW 65-100 (hydrochloride);4-ChlorophenylguanidineHCl;(4-Chlorophenyl)guanidine Hydrochlo;p-Chlorophenylguanidine Hydrochloride;4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE;Chlorhexidine Digluconate EP Impurity E;1-(4-chlorophenyl)guanidine hydrochloride;Chlorhexidine Diacetate Impurity E as Hydrochloride;Chlorhexidine Diacetate EP Impurity E as Hydrochloride;4 Chlorophenylguanidine hydrochloride,4Chlorophenylguanidine hydrochloride
CBNumber
CB1779701
Molecular Formula
C7H9Cl2N3
Formula Weight
206.07
MOL File
14279-91-5.mol
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4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Property

Melting point:
237-238 °C(Solv: water (7732-18-5))
storage temp. 
Store at RT
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Pale Green
Water Solubility 
Soluble to 100 mM in water
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
0442
Product name
4-Chlorophenylguanidinehydrochloride
Purity
≥98%(HPLC)
Packaging
100
Price
$210
Updated
2021/12/16
Usbiological
Product number
254406
Product name
4-Chlorophenylguanidine hydrochloride
Packaging
100mg
Price
$495
Updated
2021/12/16
TRC
Product number
C377740
Product name
p-​Chlorophenylguanidin​eHydrochloride
Packaging
25mg
Price
$130
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0002752
Product name
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$497.99
Updated
2021/12/16
Labseeker
Product number
SC-60354
Product name
4-CHLOROPHENYLGUANIDINEHYDROCHLORIDE
Purity
95
Packaging
10g
Price
$2475
Updated
2021/12/16
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4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

p-Chlorophenylguanidine Hydrochloride is an reagent used in the synthesis of pyrimidine derivatives as hSMG-1 inhibitors, potential targets for cancer treatment.

Biological Activity

4-chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase [1].urokinase is a serine protease. its primary physiological substrate is plasminogen, which is an inactive form of plasmin. urokinase plays an important role in vascular diseases and cancer.4-chlorophenylguanidine hydrochloride inhibited urokinase and trypsin with ki value of 6.07 μm and 120 μm, respectively [1].

storage

Store at RT

References

[1]. yang h, henkin j, kim kh, et al. selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. j med chem, 1990, 33(11): 2956-2961.

4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Suppliers

China 31 Germany 1 India 3 United Kingdom 2 United States 8 Global 45
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66

14279-91-5, 4-CHLOROPHENYLGUANIDINE HYDROCHLORIDERelated Search:

Chlorhexidine digluconate Chlorhexidine Chlorhexidine Diacetate Chlorhexidine hydrochloride picloxydine 4-CHLOROPHENYLGUANIDINE CARBONATE PROGUANIL HYDROCHLORIDE 1-(4-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Chlorhexidine diacetate Cycloguanil 4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE 1,5-BIS-(4-CHLOROPHENYL)-BIGUANIDE HCL chlorhexidine phosphanilate BUTTPARK 4\01-66 BUTTPARK 7\02-86 1-(3,4-DICHLOROPHENYL)BIGUANIDE HYDROCHLORIDE CHLORHEXIDINE-RING-UL-14C DIGLUCONATE CHLORHEXIDINE-RING-UL-14C DIHYDROCHLORIDE

  • 4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
  • 4-ChlorophenylguanidineHCl
  • p-Chlorophenylguanidine Hydrochloride
  • Chlorhexidine Digluconate EP Impurity E
  • (4-Chlorophenyl)guanidine Hydrochlo
  • 1-(4-chlorophenyl)guanidine hydrochloride
  • BW 65-100 (hydrochloride)
  • 4 Chlorophenylguanidine hydrochloride,4Chlorophenylguanidine hydrochloride
  • Chlorhexidine Diacetate Impurity E as Hydrochloride
  • Chlorhexidine Diacetate EP Impurity E as Hydrochloride
  • 14279-91-5
  • C7H9Cl2N3
  • C7H8CIN3HCl