ETHYLMALONIC ACID
- Product Name
- ETHYLMALONIC ACID
- CAS No.
- 601-75-2
- Chemical Name
- ETHYLMALONIC ACID
- Synonyms
- ETHYLMALONIC ACID;2-Ethylmalonicaci;2-Ethylmalonic acid;RARECHEM DK HD C012;EthylmalonicAcid>Malonic acid, ethyl-;2-ethylpropanedioate;Ethyl propoinic acid;Ethylmalonicacid,98%;Ethylmalonic acid 97%
- CBNumber
- CB1782664
- Molecular Formula
- C5H8O4
- Formula Weight
- 132.11
- MOL File
- 601-75-2.mol
ETHYLMALONIC ACID Property
- Melting point:
- 112-114 °C (lit.)
- Boiling point:
- 292.77°C (rough estimate)
- Density
- 1.5633 (rough estimate)
- refractive index
- 1.4016 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- pK1:2.90(0);pK2:5.55(+1) (25°C)
- color
- Off-White
- Water Solubility
- Soluble in water, methanol (very faint turbidity), and ethanol.
- BRN
- 774334
- InChI
- 1S/C5H8O4/c1-2-3(4(6)7)5(8)9/h3H,2H2,1H3,(H,6,7)(H,8,9)
- InChIKey
- UKFXDFUAPNAMPJ-UHFFFAOYSA-N
- SMILES
- CCC(C(O)=O)C(O)=O
- CAS DataBase Reference
- 601-75-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Ethylmalonic acid(601-75-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 102687
- Product name
- Ethylmalonic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $70.5
- Updated
- 2025/07/31
- Product number
- 102687
- Product name
- Ethylmalonic acid
- Purity
- 97%
- Packaging
- 50g
- Price
- $361
- Updated
- 2025/07/31
- Product number
- E0137
- Product name
- Ethylmalonic Acid
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $89
- Updated
- 2025/07/31
- Product number
- E0137
- Product name
- Ethylmalonic Acid
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $357
- Updated
- 2025/07/31
- Product number
- E922020
- Product name
- Ethylmalonic Acid
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
ETHYLMALONIC ACID Chemical Properties,Usage,Production
Chemical Properties
white to faintly pink crystalline powder
Uses
Ethylmalonic acid is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.
Definition
ChEBI: Ethylmalonic acid is a dicarboxylic acid obtained by substitution of one of the methylene hydrogens of malonic acid by an ethyl group. It has a role as a human metabolite. It is a dicarboxylic acid and a dicarboxylic fatty acid. It is functionally related to a malonic acid. It is a conjugate acid of an ethylmalonate and an ethylmalonate(2-).
Synthesis
6148-64-7
601-75-2
Step 2: In a 250 mL three-necked flask equipped with a magnetic stirrer, a dosing funnel and a thermometer, monoethyl malonate potassium salt (17.77 g, 104.49 mmol) was dissolved in 18 mL of water. The reaction mixture was cooled in an ice bath and 8 mL of concentrated hydrochloric acid (about 2 mL) was added slowly and dropwise. Upon completion of the reaction, the mixture was filtered to remove the resulting KCl precipitate and the precipitate was washed with ether (3 x 50 mL). The filtrate was separated and the aqueous phase was further extracted with ether (3 x 50 mL). All ether phases were combined, dried with anhydrous MgSO4, filtered and concentrated under reduced pressure to give the colorless oily product ethylmalonic acid (13.45 g, 82% overall yield in two steps).
IC 50
Human Endogenous Metabolite
References
[1] Patent: US6780887, 2004, B1
ETHYLMALONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYLMALONIC ACID manufacturers
- Product
- Ethylmalonic acid 601-75-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-28
- Product
- ETHYLMALONIC ACID 601-75-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-13