Nesvacumab

Product Name: Nesvacumab
CAS No.: 1296818-77-3
Chemical Name: Nesvacumab
Synonyms: Nesvacumab;Nesvacumab (anti-ANGPT2);Research Grade Nesvacumab;Research Grade Nesvacumab(DHA42303)
CBNumber: CB18080874
Formula Weight: 0
MOL File: Mol file

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Nesvacumab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Nesvacumab Chemical Properties,Usage,Production

Uses

Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1[1].

Biological Activity

Nesvacumab is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2. As of May 2017, it is in Phase II clinical trials for the treatment of diabetic macular edema.

References

[1] Kyriakos P Papadopoulos, et al. A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clin Cancer Res. 2016 Mar 15;22(6):1348-55. DOI:10.1158/1078-0432.CCR-15-1221

Nesvacumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Nesvacumab Suppliers

China 17 Global 17

Shanghai YuanYe Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Biolab Reagents

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1296818-77-3, NesvacumabRelated Search:

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Nesvacumab

Research Grade Nesvacumab(DHA42303)

Research Grade Nesvacumab

Nesvacumab (anti-ANGPT2)

1296818-77-3