ChemicalBook > CAS DataBase List > Epcoritamab
Epcoritamab
- Product Name
- Epcoritamab
- CAS No.
- 2134641-34-0
- Chemical Name
- Epcoritamab
- Synonyms
- Epcoritamab;Research Grade Epcoritamab
- CBNumber
- CB18081169
- Formula Weight
- 0
- MOL File
- Mol file
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Epcoritamab Property
- form
- Liquid
- color
- Colorless to light yellow
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Epcoritamab Chemical Properties,Usage,Production
Uses
Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines[1].
References
[1] van der Horst HJ, et al. Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatment. Blood Cancer J. 2021 Feb 18;11(2):38. DOI:10.1038/s41408-021-00430-6
[2] Thieblemont C, et al. Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell-Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial. J Clin Oncol. 2023 Apr 20;41(12):2238-2247. DOI:10.1200/JCO.22.01725
Epcoritamab Preparation Products And Raw materials
Raw materials
Preparation Products
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Epcoritamab Suppliers
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- 177-54423994 17754423994
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