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ChemicalBook > CAS DataBase List > 4-BROMO-2-IODOPHENOL

4-BROMO-2-IODOPHENOL

Application
Product Name
4-BROMO-2-IODOPHENOL
CAS No.
207115-22-8
Chemical Name
4-BROMO-2-IODOPHENOL
Synonyms
2-Iodo-4-bromophenol;4-BROMO-2-IODOPHENOL;Phenol, 4-bromo-2-iodo-;4-Bromo-2-iodophenol98%;4-Bromo-2-iodophenol 98%;4-BROMO-2-IODOPHENOL ISO 9001:2015 REACH
CBNumber
CB1838862
Molecular Formula
C6H4BrIO
Formula Weight
298.9
MOL File
207115-22-8.mol
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4-BROMO-2-IODOPHENOL Property

Melting point:
90℃ (ethanol )
Boiling point:
243.0±25.0℃ (760 Torr)
Density 
2.369±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
100.8±23.2℃
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder to crystal
pka
7.94±0.18(Predicted)
color 
White to Light yellow to Light orange
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Safety

HS Code 
2908190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4957
Product name
4-Bromo-2-iodophenol
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$106
Updated
2025/07/31
TCI Chemical
Product number
B4957
Product name
4-Bromo-2-iodophenol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$255
Updated
2025/07/31
TRC
Product number
B683913
Product name
4-Bromo-2-iodophenol
Packaging
250mg
Price
$55
Updated
2021/12/16
Apolloscientific
Product number
OR52087
Product name
4-Bromo-2-iodophenol
Purity
98%
Packaging
1g
Price
$41
Updated
2021/12/16
SynQuest Laboratories
Product number
2601-S-X1
Product name
4-Bromo-2-iodophenol
Packaging
1g
Price
$45
Updated
2021/12/16
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4-BROMO-2-IODOPHENOL Chemical Properties,Usage,Production

Application

4-Bromo-2-iodophenol, also known as 2-iodo-4-bromophenol, is an organic intermediate that can be prepared by nitration and reduction of p-bromophenol followed by diazotization and iodination.

Synthesis

533-58-4

207115-22-8

General procedure for the synthesis of 4-bromo-2-iodophenol (4) from 2-iodophenol: 2-iodophenol (11 g, 50 mmol) was dissolved in a solvent mixture of dichloromethane (DCM, 200 mL) and methanol (MeOH, 100 mL). Subsequently, tetrabutylammonium tribromide (TBATB, 25.31 g, 52.5 mmol) was added in batches over 10 min. The reaction mixture was stirred at room temperature for 2 h before the reaction was quenched with 1N hydrochloric acid (HCl, 200 mL). The organic layer (DCM layer) was separated and the aqueous layer was extracted twice more with dichloromethane (DCM). All organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by fast column chromatography (silica gel, 50%-100% dichloromethane/hexane gradient elution) to afford the target product 4-bromo-2-iodophenol (10.2 g, 68% yield).

References

[1] Tetrahedron, 2015, vol. 71, # 35, p. 5946 - 5951
[2] Journal of Organic Chemistry, 2013, vol. 78, # 17, p. 8680 - 8688
[3] Organic Letters, 2015, vol. 17, # 22, p. 5666 - 5669
[4] Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1931, vol. 192, p. 1037
[5] Canadian Journal of Chemistry, 1965, vol. 43, p. 650 - 658

4-BROMO-2-IODOPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-BROMO-2-IODOPHENOL manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-BROMO-2-IODOPHENOL 207115-22-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-07-05
Career Henan Chemical Co
Product
4-BROMO-2-IODOPHENOL 207115-22-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-09

207115-22-8, 4-BROMO-2-IODOPHENOLRelated Search:


  • 4-BROMO-2-IODOPHENOL
  • 2-Iodo-4-bromophenol
  • 4-Bromo-2-iodophenol 98%
  • 4-Bromo-2-iodophenol98%
  • Phenol, 4-bromo-2-iodo-
  • 4-BROMO-2-IODOPHENOL ISO 9001:2015 REACH
  • 207115-22-8