2-Iodophenol
- Product Name
- 2-Iodophenol
- CAS No.
- 533-58-4
- Chemical Name
- 2-Iodophenol
- Synonyms
- O-IODOPHENOL;ORTHO-IODOPHENOL;DK807;NSC 9245;o-Jodfenol;2-Jodfenol;2-iodo-pheno;2-IODOPHENOL;o-iodo-pheno;2-lodophenol
- CBNumber
- CB4130718
- Molecular Formula
- C6H5IO
- Formula Weight
- 220.01
- MOL File
- 533-58-4.mol
2-Iodophenol Property
- Melting point:
- 37-40 °C (lit.)
- Boiling point:
- 186-187 °C/160 mmHg (lit.)
- Density
- 1.947 g/mL at 25 °C (lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Crystalline Powder or Crystalline Low Melting Mass
- pka
- 8.51(at 25℃)
- Specific Gravity
- 1.947
- color
- White or cream to brown
- Water Solubility
- slightly soluble
- Sensitive
- Light Sensitive
- Merck
- 14,5035
- BRN
- 1855300
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- KQDJTBPASNJQFQ-UHFFFAOYSA-N
- CAS DataBase Reference
- 533-58-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Phenol, 2-iodo-(533-58-4)
- EPA Substance Registry System
- Phenol, 2-iodo- (533-58-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- SL5500000
- TSCA
- T
- HazardClass
- IRRITANT, LIGHT SENSITIVE
- HS Code
- 29081000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 281409
- Product name
- 2-Iodophenol
- Purity
- 98%
- Packaging
- 5g
- Price
- $60.4
- Updated
- 2024/03/01
- Product number
- 281409
- Product name
- 2-Iodophenol
- Purity
- 98%
- Packaging
- 25g
- Price
- $121
- Updated
- 2024/03/01
- Product number
- I0460
- Product name
- 2-Iodophenol
- Purity
- >99.0%(GC)
- Packaging
- 5g
- Price
- $41
- Updated
- 2024/03/01
- Product number
- I0460
- Product name
- 2-Iodophenol
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $134
- Updated
- 2024/03/01
- Product number
- A13599
- Product name
- 2-Iodophenol, 98%
- Packaging
- 5g
- Price
- $34.65
- Updated
- 2024/03/01
2-Iodophenol Chemical Properties,Usage,Production
Chemical Properties
colorless needle-like crystals or Pale Yellow Low Melting Solid. Slightly soluble in water, easily soluble in organic solvents such as ethanol and ether.
Uses
2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.
Application
2-Iodophenol is a halophenol with antifungal activity. 2-Iodophenol was used in the synthesis of:
aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity
3,3-disubstituted-2,3-dihydrobenzofurans
1,3,5-substituted benzenes.
2-Iodophenol is also used as additive tracers for resist plasm a etching and suzuki reaction.
Preparation
synthesis of 2-iodophenol: phenol (1a) to react with 0.5 equivalent of iodine and 1 equivalent of hydrogen peroxide in water at room temperature for 24 h, 2,6-diiodophenol (2a) and 2-iodophenol (3) were isolated in yields of 21 and 49%, respectively.
Definition
ChEBI: 2-iodophenol is a 2-halophenol and an iodophenol.
Synthesis Reference(s)
The Journal of Organic Chemistry, 53, p. 5281, 1988 DOI: 10.1021/jo00257a014
General Description
Rapid palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with various alkyne under microwave irradiation using Mo(CO)6 as the CO source has been investigated.
Purification Methods
Crystallise 2-iodophenol from CHCl3 or diethyl ether. The acetate has m 65-66o (from MeOH). [Beilstein 6 H 208, 6 II 198, 6 III 774, 6 IV 1074.]
2-Iodophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Iodophenol manufacturers
- Product
- 2-Iodophenol 533-58-4
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-24
- Product
- 2-Iodophenol 533-58-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2023-04-27
- Product
- 2-Iodophenol 533-58-4
- Price
- US $30.00-10.00/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 100000kg
- Release date
- 2023-04-11