2-Iodophenol

Product Name: 2-Iodophenol
CAS No.: 533-58-4
Chemical Name: 2-Iodophenol
Synonyms: O-IODOPHENOL;ORTHO-IODOPHENOL;DK807;NSC 9245;o-Jodfenol;2-Jodfenol;2-iodo-pheno;2-IODOPHENOL;o-iodo-pheno;2-lodophenol
CBNumber: CB4130718
Molecular Formula: C6H5IO
Formula Weight: 220.01
MOL File: 533-58-4.mol

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2-Iodophenol Property

Melting point:: 37-40 °C (lit.)
Boiling point:: 186-187 °C/160 mmHg (lit.)
Density: 1.947 g/mL at 25 °C (lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Crystalline Powder or Crystalline Low Melting Mass
pka: 8.51(at 25℃)
color: White or cream to brown
Specific Gravity: 1.947
Water Solubility: slightly soluble
Sensitive: Light Sensitive
Merck: 14,5035
BRN: 1855300
Stability:: Stable. Incompatible with strong oxidizing agents.
InChI: 1S/C6H5IO/c7-5-3-1-2-4-6(5)8/h1-4,8H
InChIKey: KQDJTBPASNJQFQ-UHFFFAOYSA-N
SMILES: Oc1ccccc1I
CAS DataBase Reference: 533-58-4(CAS DataBase Reference)
NIST Chemistry Reference: Phenol, 2-iodo-(533-58-4)
EPA Substance Registry System: Phenol, 2-iodo- (533-58-4)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: SL5500000
TSCA: TSCA listed
HazardClass: IRRITANT, LIGHT SENSITIVE
HS Code: 29081000
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 281409
Product name: 2-Iodophenol
Purity: 98%
Packaging: 5g
Price: $43.61
Updated: 2025/07/31

Sigma-Aldrich

Product number: 281409
Product name: 2-Iodophenol
Purity: 98%
Packaging: 25g
Price: $125
Updated: 2025/07/31

TCI Chemical

Product number: I0460
Product name: 2-Iodophenol
Purity: >99.0%(GC)
Packaging: 5g
Price: $41
Updated: 2025/07/31

TCI Chemical

Product number: I0460
Product name: 2-Iodophenol
Purity: >99.0%(GC)
Packaging: 25g
Price: $134
Updated: 2025/07/31

TRC

Product number: I717500
Product name: 2-Iodophenol
Packaging: 5g
Price: $45
Updated: 2021/12/16

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2-Iodophenol Chemical Properties,Usage,Production

Chemical Properties

colorless needle-like crystals or Pale Yellow Low Melting Solid. Slightly soluble in water, easily soluble in organic solvents such as ethanol and ether.

Uses

2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.

Application

2-Iodophenol is a halophenol with antifungal activity. 2-Iodophenol was used in the synthesis of:
aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity
3,3-disubstituted-2,3-dihydrobenzofurans
1,3,5-substituted benzenes.
2-Iodophenol is also used as additive tracers for resist plasm a etching and suzuki reaction.

Preparation

synthesis of 2-iodophenol: phenol (1a) to react with 0.5 equivalent of iodine and 1 equivalent of hydrogen peroxide in water at room temperature for 24 h, 2,6-diiodophenol (2a) and 2-iodophenol (3) were isolated in yields of 21 and 49%, respectively.

Definition

ChEBI: 2-iodophenol is a 2-halophenol and an iodophenol.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 5281, 1988 DOI: 10.1021/jo00257a014

General Description

Rapid palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with various alkyne under microwave irradiation using Mo(CO)₆ as the CO source has been investigated.

Purification Methods

Crystallise 2-iodophenol from CHCl3 or diethyl ether. The acetate has m 65-66o (from MeOH). [Beilstein 6 H 208, 6 II 198, 6 III 774, 6 IV 1074.]

2-Iodophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Iodophenol Suppliers

Americas 1 Belgium 1 Canada 3 China 330 Europe 3 Germany 6 India 41 Japan 5 Slovakia 1 Switzerland 2 United Kingdom 17 United States 44 Global 454

Suzhou chems bio-tech.co.,Ltd.

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J & K SCIENTIFIC LTD.

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Alfa Aesar

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TAIYUAN RHF CO.,LTD.

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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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ProdList: 24529
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View Lastest Price from 2-Iodophenol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Iodophenol 533-58-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2025-03-10

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Iodophenol 533-58-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-25

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2-Iodophenol 533-58-4
Price: US $30.00-10.00/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 100000kg
Release date: 2024-08-14

533-58-4, 2-IodophenolRelated Search:

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Adjacent iodine phenol

2-IODOPHENOL

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2-iodo-pheno

2-Jodfenol

o-iodo-pheno

o-Jodfenol

Phenol, o-iodo-

PHENOL, 2-IODO-

O-IODOPHENOL

ORTHO-IODOPHENOL

o-iodophenic acid

1-Hydroxy-2-iodobenzene

2-Iodophenol, 98% 5GR

o-Iodophenol 2-Iodophenol

2-Iodophenol,98%

NSC 9245

2-lodophenol

2-Iodophenol&gt

533-58-4 2-Iodophenol

DK807

2-Iodophenol, 95%

533-58-4

C6H7IN

ALCOHOL

Organic Building Blocks

Oxygen Compounds

Phenols

Building Blocks

C6 to C8

Chemical Synthesis

Organic Building Blocks

Oxygen Compounds

Aromatic Phenols

Phenol&Thiophenol&Mercaptan

Iodine Compounds

Phenols

Phenyls & Phenyl-Het

Organic Building Blocks

Oxygen Compounds

alcohol| alkyl Iodine