5,7-DIMETHOXY-INDAN-1-ONE
Uses- Product Name
- 5,7-DIMETHOXY-INDAN-1-ONE
- CAS No.
- 880-87-5
- Chemical Name
- 5,7-DIMETHOXY-INDAN-1-ONE
- Synonyms
- 5,7-Dimethoxy-1-indanone;5,7-DIMETHOXY-INDAN-1-ONE;5,7-dimethoxy-2,3-dihydroinden-1-one;5,7-diMethoxy-2,3-dihydro-1H-inden-1-one;2,3-Dihydro-5,7-dimethoxy-1H-inden-1-one;1H-Inden-1-one, 2,3-dihydro-5,7-dimethoxy-
- CBNumber
- CB1841583
- Molecular Formula
- C11H12O3
- Formula Weight
- 192.21
- MOL File
- 880-87-5.mol
5,7-DIMETHOXY-INDAN-1-ONE Property
- Melting point:
- 99-100 °C
- Boiling point:
- 352.6±42.0 °C(Predicted)
- Density
- 1.34 g/cm3
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D470535
- Product name
- 5,7-Dimethoxyindan-1-one
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 4040AC
- Product name
- 5,7-Dimethoxyindan-1-one
- Packaging
- 250mg
- Price
- $91
- Updated
- 2021/12/16
- Product number
- CHM0079787
- Product name
- 5,7-DIMETHOXY-INDAN-1-ONE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1899.98
- Updated
- 2021/12/16
- Product number
- H-2426
- Product name
- 5,7-Dimethoxy-1-indanone
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $146.67
- Updated
- 2021/12/16
- Product number
- CM185996
- Product name
- 5,7-DIMETHOXY-INDAN-1-ONE
- Purity
- 95%
- Packaging
- 1g
- Price
- $194
- Updated
- 2021/12/16
5,7-DIMETHOXY-INDAN-1-ONE Chemical Properties,Usage,Production
Uses
5,7-Dimethoxyindan-1-one acts as a reagent for the preparation and antitumor activities of phenyl- and benzothiazolylisoquinolinedienes.
Uses
5,7-Dimethoxyindan-1-one acts as a reagent for the preparation and antitumor activities of phenyl- and benzothiazolylisoquinolinedienes.
Synthesis
717-94-2
880-87-5
The general procedure for the synthesis of 5,7-dimethoxyindanone from 3,5-dimethoxyphenylpropionic acid was as follows: 3-(3,5-dimethoxyphenyl)propionic acid (2 g x 5) was dissolved in methanesulfonic acid (10 ml x 5) in a microwave treated vial (20 ml x 5). The reaction mixture was heated at 90°C for 10 min under microwave radiation. After completion of the reaction, the mixture was slowly poured into ice (250 g) and neutralized to pH 8-9 with 2 M NaOH solution, followed by extraction with EtOAc. The organic layers were combined and the target product 5,7-dimethoxyindanone (8.8 g, 96.2% yield) was obtained after concentration. The product was analyzed by LC-MS and showed m/e 193 (MH+).
References
[1] Chemistry - An Asian Journal, 2015, vol. 10, # 4, p. 1050 - 1064
[2] Tetrahedron, 2007, vol. 63, # 2, p. 389 - 395
[3] Patent: WO2007/71348, 2007, A1. Location in patent: Page/Page column 87
[4] ChemMedChem, 2018, vol. 13, # 18, p. 1949 - 1956
[5] Tetrahedron Letters, 1980, vol. 21, # 37, p. 3603 - 3606
5,7-DIMETHOXY-INDAN-1-ONE Preparation Products And Raw materials
Raw materials
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View Lastest Price from 5,7-DIMETHOXY-INDAN-1-ONE manufacturers
- Product
- 5,7-DIMETHOXY-INDAN-1-ONE 880-87-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 100kg
- Release date
- 2020-01-10