ChemicalBook > CAS DataBase List > 5-Chloro-1-indanone

5-Chloro-1-indanone

Product Name
5-Chloro-1-indanone
CAS No.
42348-86-7
Chemical Name
5-Chloro-1-indanone
Synonyms
5-Chloro-2,3-dihydro-1H-inden-1-one;Chloro-1-indan;5-Chloro Indanone;5- chlorineindone;5-CHLORO-1-INDANONE;5-CHLOROINDAN-1-ONE;1-Indanone, 5-chloro-;5-Chloro-1-indanone,98%;5-Chloro-1-indanone,99%;5-Chloro-1-indanone >
CBNumber
CB2148511
Molecular Formula
C9H7ClO
Formula Weight
166.6
MOL File
42348-86-7.mol
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5-Chloro-1-indanone Property

Melting point:
94-98 °C (lit.)
Boiling point:
124-125 °C (3 mmHg)
Density 
1.1466 (rough estimate)
refractive index 
1.6000 (estimate)
Flash point:
124-125°C/3mm
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly)
form 
Solid
color 
Light Beige to Beige
Water Solubility 
insoluble
BRN 
1448000
InChIKey
MEDSHTHCZIOVPU-UHFFFAOYSA-N
CAS DataBase Reference
42348-86-7(CAS DataBase Reference)
NIST Chemistry Reference
5-Chloro-1-indanone(42348-86-7)
EPA Substance Registry System
1H-Inden-1-one, 5-chloro-2,3-dihydro- (42348-86-7)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
433071
Product name
5-Chloro-1-indanone
Purity
99%
Packaging
5g
Price
$62.3
Updated
2024/03/01
TCI Chemical
Product number
C1644
Product name
5-Chloro-1-indanone
Purity
>97.0%(GC)
Packaging
1g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
C1644
Product name
5-Chloro-1-indanone
Purity
>97.0%(GC)
Packaging
5g
Price
$212
Updated
2024/03/01
Alfa Aesar
Product number
A18308
Product name
5-Chloro-1-indanone, 99%
Packaging
1g
Price
$46.65
Updated
2024/03/01
Alfa Aesar
Product number
A18308
Product name
5-Chloro-1-indanone, 99%
Packaging
5g
Price
$180.65
Updated
2024/03/01
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5-Chloro-1-indanone Chemical Properties,Usage,Production

Chemical Properties

White Crystal

Uses

5-Chloro-1-indanone is the important intermediate of du pont company's new varieties of pesticides indoxacarb (popular name: indoxacarb), is also a kind of important medicine intermediate simultaneously.
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors.

Uses

5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.

Preparation

3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃.
Synthetic method of 5-chloro-1-indanone

General Description

5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.

5-Chloro-1-indanone Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-1-indanone Suppliers

Fuxin Simai Chemical Technology Co., Ltd.
Tel
13841818553
Email
929964679@qq.com
Country
China
ProdList
446
Advantage
58
Suzhou Runsen Pharmaceutical Technology Co., Ltd.
Tel
0512-65885589 18751140360
Fax
0512-65885589
Email
sales@rosen-chemicals.com
Country
China
ProdList
313
Advantage
58
Beijing Yibai Biotechnology Co., Ltd.
Tel
16600087706
Fax
86-010-60404860
Email
shadow@yibaibiotech.com
Country
China
ProdList
40
Advantage
58
Shandong Yukun Chemical Industry Co. LTD
Tel
18660690289
Email
sales@yukunchem.com
Country
China
ProdList
45
Advantage
58
Shenyang Kelaishen Chemical Products Co., Ltd.
Tel
15840211838; 15840211838
Fax
18640376777
Email
15840211838@163.com
Country
China
ProdList
14
Advantage
58
Shanghai Tuolei Chemical Reagents Co., Ltd.
Tel
86-021-50318510
Fax
021-58650104
Country
China
ProdList
69
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
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View Lastest Price from 5-Chloro-1-indanone manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
5-Chloro-1-Indanone 42348-86-7
Price
US $100.00-60.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-22
Zhengzhou Anbu Chem Co.,Ltd
Product
5-Chloro-1-indanone 42348-86-7
Price
US $0.00/KG
Min. Order
0.1KG
Purity
98%
Supply Ability
1000KGS
Release date
2023-07-14
Changzhou waston chemical technology Co.,Ltd
Product
5-Chloro-1-indanone 42348-86-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
As your request
Release date
2024-07-01

42348-86-7, 5-Chloro-1-indanoneRelated Search:


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