5-Chloroindole
- Product Name
- 5-Chloroindole
- CAS No.
- 17422-32-1
- Chemical Name
- 5-Chloroindole
- Synonyms
- 5-CHLORO-1H-INDOLE;oroindoL;ChloroIndole;5-CHLOROINDOLE;6-Chloroindole99%;5-CHLOROINDOLE99%;5-Chloroindole 98%;5-Chloroindole >5-Chloroindole ,98%;1H-Indole,5-chloro-
- CBNumber
- CB2126773
- Molecular Formula
- C8H6ClN
- Formula Weight
- 151.59
- MOL File
- 17422-32-1.mol
5-Chloroindole Property
- Melting point:
- 69-71 °C (lit.)
- Boiling point:
- 130 °C / 0.4mmHg
- Density
- 1.1976 (rough estimate)
- refractive index
- 1.5437 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in alcohol.
- form
- Crystalline Powder
- pka
- 16.09±0.30(Predicted)
- color
- White to slightly grayish-green
- BRN
- 2651
- InChIKey
- MYTGFBZJLDLWQG-UHFFFAOYSA-N
- CAS DataBase Reference
- 17422-32-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 22-24/25-36-26-37/39
- RIDADR
- 2811
- WGK Germany
- 3
- F
- 10
- HazardClass
- IRRITANT
- HS Code
- 29339990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C47604
- Product name
- 5-Chloroindole
- Purity
- 98%
- Packaging
- 1g
- Price
- $44.58
- Updated
- 2024/03/01
- Product number
- C47604
- Product name
- 5-Chloroindole
- Purity
- 98%
- Packaging
- 5g
- Price
- $80.4
- Updated
- 2024/03/01
- Product number
- C1107
- Product name
- 5-Chloroindole
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $86
- Updated
- 2024/03/01
- Product number
- C1107
- Product name
- 5-Chloroindole
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $254
- Updated
- 2024/03/01
- Product number
- 006333
- Product name
- 5-Chloroindole
- Packaging
- 2.5g
- Price
- $446
- Updated
- 2021/12/16
5-Chloroindole Chemical Properties,Usage,Production
Chemical Properties
White to slightly greyish-green crystalline powder
Uses
5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels in the brainstem and telencephalon.
Uses
5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts. 5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 29, p. 1625, 1992 DOI: 10.1002/jhet.5570290644
The Journal of Organic Chemistry, 44, p. 578, 1979 DOI: 10.1021/jo01318a021
General Description
5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT3 receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.
Purification Methods
It is distilled at high vacuum and recrystallises from pet ether (b 40-60o) or (b 80-100o) as glistening plates. The picrate has m 147o (146.5-147.5o)(from *C6H6). [Rydon & Tweddle J Chem Soc 3499 1955, Sugasawa J Org Chem 44 578 1979, Beilstein 20/4 V 34.]
5-Chloroindole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloroindole manufacturers
- Product
- 5-Chloroindole 17422-32-1
- Price
- US $35.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2022-12-27
- Product
- 5-Chloroindole 17422-32-1
- Price
- US $80.00-55.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-05
- Product
- 5-Chloroindole 17422-32-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-10-21