ChemicalBook > CAS DataBase List > 5-Chloroindole

5-Chloroindole

Product Name
5-Chloroindole
CAS No.
17422-32-1
Chemical Name
5-Chloroindole
Synonyms
5-CHLORO-1H-INDOLE;oroindoL;ChloroIndole;5-CHLOROINDOLE;6-Chloroindole99%;5-CHLOROINDOLE99%;5-Chloroindole 98%;5-Chloroindole >5-Chloroindole ,98%;1H-Indole,5-chloro-
CBNumber
CB2126773
Molecular Formula
C8H6ClN
Formula Weight
151.59
MOL File
17422-32-1.mol
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5-Chloroindole Property

Melting point:
69-71 °C (lit.)
Boiling point:
130 °C / 0.4mmHg
Density 
1.1976 (rough estimate)
refractive index 
1.5437 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in alcohol.
form 
Crystalline Powder
pka
16.09±0.30(Predicted)
color 
White to slightly grayish-green
BRN 
2651
InChIKey
MYTGFBZJLDLWQG-UHFFFAOYSA-N
CAS DataBase Reference
17422-32-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
22-24/25-36-26-37/39
RIDADR 
2811
WGK Germany 
3
10
HazardClass 
IRRITANT
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C47604
Product name
5-Chloroindole
Purity
98%
Packaging
1g
Price
$44.58
Updated
2024/03/01
Sigma-Aldrich
Product number
C47604
Product name
5-Chloroindole
Purity
98%
Packaging
5g
Price
$80.4
Updated
2024/03/01
TCI Chemical
Product number
C1107
Product name
5-Chloroindole
Purity
>98.0%(GC)
Packaging
5g
Price
$86
Updated
2024/03/01
TCI Chemical
Product number
C1107
Product name
5-Chloroindole
Purity
>98.0%(GC)
Packaging
25g
Price
$254
Updated
2024/03/01
Usbiological
Product number
006333
Product name
5-Chloroindole
Packaging
2.5g
Price
$446
Updated
2021/12/16
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5-Chloroindole Chemical Properties,Usage,Production

Chemical Properties

White to slightly greyish-green crystalline powder

Uses

5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels in the brainstem and telencephalon.

Uses

5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts. 5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 29, p. 1625, 1992 DOI: 10.1002/jhet.5570290644
The Journal of Organic Chemistry, 44, p. 578, 1979 DOI: 10.1021/jo01318a021

General Description

5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT3 receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.

Purification Methods

It is distilled at high vacuum and recrystallises from pet ether (b 40-60o) or (b 80-100o) as glistening plates. The picrate has m 147o (146.5-147.5o)(from *C6H6). [Rydon & Tweddle J Chem Soc 3499 1955, Sugasawa J Org Chem 44 578 1979, Beilstein 20/4 V 34.]

5-Chloroindole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloroindole Suppliers

Chongqing TianyiHenghua Technology Co., Ltd.
Tel
15086758486; 15086758486
Fax
-
Email
chemtyhh@163.com
Country
China
ProdList
86
Advantage
58
Wuhan Luyi New Material Co., Ltd.
Tel
027-81360608 13971310049
Fax
027-81360608
Email
109321999@qq.com
Country
China
ProdList
72
Advantage
58
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
971
Advantage
62
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
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View Lastest Price from 5-Chloroindole manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
5-Chloroindole 17422-32-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-29
Henan Aochuang Chemical Co.,Ltd.
Product
5-Chloroindole 17422-32-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Chemwill Asia Co.,Ltd.
Product
5-Chloroindole in stock Factory 17422-32-1
Price
US $1.00/KG
Min. Order
1KG
Purity
TOP 3 Factory in China
Supply Ability
Top 3 largest production capacity Factory
Release date
2019-04-03

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