5-Chloro-2-nitrotoluene
Application- Product Name
- 5-Chloro-2-nitrotoluene
- CAS No.
- 5367-28-2
- Chemical Name
- 5-Chloro-2-nitrotoluene
- Synonyms
- 5-Chloro-2-nit;3-chloro-6-nitrotoluene;5-CHLORO-2-NITROTOLUENE;5-chloro-2-nitro-toluen;2-Nitro-5-chlorotoluene;Toluene, 5-chloro-2-nitro-;5-Chloro-2-nitrotoluene,98%;5-Chloro-2-nitrotoluene >3-Methyl-4-nitrochlorobenzene;1-Chloro-3-methyl-4-nitrobenzene
- CBNumber
- CB2265005
- Molecular Formula
- C7H6ClNO2
- Formula Weight
- 171.58
- MOL File
- 5367-28-2.mol
5-Chloro-2-nitrotoluene Property
- Melting point:
- 27-30 °C (lit.)
- Boiling point:
- 124-126 °C (16 mmHg)
- Density
- 1.32
- refractive index
- 1.57-1.572
- Flash point:
- 202 °F
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to lump
- color
- White to Light yellow
- Water Solubility
- insoluble
- CAS DataBase Reference
- 5367-28-2(CAS DataBase Reference)
- NIST Chemistry Reference
- 5-Chloro-2-nitrotoluene(5367-28-2)
Safety
- Hazard Codes
- Xn,N
- Risk Statements
- 22-36-36/37/38-20/21/22-52/53
- Safety Statements
- 26-36-36/37/39-61
- RIDADR
- UN 3457 6.1/PG 3
- WGK Germany
- 3
- RTECS
- XS9134000
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29049090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 226653
- Product name
- 5-Chloro-2-nitrotoluene
- Purity
- 98%
- Packaging
- 25g
- Price
- $21.45
- Updated
- 2025/07/31
- Product number
- C2586
- Product name
- 5-Chloro-2-nitrotoluene
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $23
- Updated
- 2025/07/31
- Product number
- C2586
- Product name
- 5-Chloro-2-nitrotoluene
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $70
- Updated
- 2025/07/31
- Product number
- C382403
- Product name
- 5-Chloro-2-nitrotoluene
- Packaging
- 10g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- J92361
- Product name
- 5-Chloro-2-nitrotoluene
- Packaging
- 500g
- Price
- $180
- Updated
- 2021/12/16
5-Chloro-2-nitrotoluene Chemical Properties,Usage,Production
Application
5-Chloro-2-nitrotoluene is an organic intermediate that can be obtained by nitrifying o-chlorotoluene.
Chemical Properties
clear yellow liquid
General Description
The cytotoxicity of 5-chloro-2-nitrotoluene, an analog of chlorphenamidine, was studied.
Synthesis
108-41-8
5367-28-2
38939-88-7
General procedure for the synthesis of 5-chloro-2-nitrotoluene and 3-chloro-4-nitrotoluene from 3-chlorotoluene: Concentrated nitric acid (16 mL) was added slowly and dropwise at 0°C to a solution of glacial acetic acid (20 mL) containing 3-chlorotoluene (3 mL, 25.4 mmol) and concentrated sulfuric acid (6 mL). The reaction mixture was stirred at room temperature for 24 hours. Subsequently, the reaction mixture was poured into ice water and liquid-liquid partitioned with ether. After separating the aqueous phase, the aqueous phase was extracted twice with ether. The organic phases were combined, washed sequentially with water and brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The yellow oily crude product obtained was purified by silica gel column chromatography and after two rapid chromatographic separations, 1.22 g (14% yield) of 5-chloro-2-nitrotoluene (yellow oily) and 3.39 g (39% yield) of 3-chloro-4-nitrotoluene were obtained.
References
[1] Patent: US2012/15962, 2012, A1. Location in patent: Page/Page column 83
[2] Chemische Berichte, 1900, vol. 33, p. 2505
[3] Bulletin de la Societe Chimique de France, 1900, vol. <3> 23, p. 838
[4] Chemische Berichte, 1900, vol. 33, p. 2505,2506
5-Chloro-2-nitrotoluene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloro-2-nitrotoluene manufacturers
- Product
- 5-Chloro-2-nitrotoluene 5367-28-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-28
- Product
- 5-Chloro-2-nitrotoluene 5367-28-2
- Price
- US $6.00/KG
- Min. Order
- 2KG
- Purity
- 98%
- Supply Ability
- 1KG,50KG,100KG
- Release date
- 2019-09-03