Methyl 5-chloro-2-nitrobenzoate
- Product Name
- Methyl 5-chloro-2-nitrobenzoate
- CAS No.
- 51282-49-6
- Chemical Name
- Methyl 5-chloro-2-nitrobenzoate
- Synonyms
- RARECHEM AL BF 0190;METHYL 5-CHLORO-2-NITROBENZOATE;METHYL 5-CHLORO-2-NITROBENZONATE;METHYL (2-NITRO-5-CHLORO)BENZOATE;5-chloro-3-methyl-2-nitrobenzoate;Methyl5-Chloro-2-nitrobenzoate>METHYL 5-CHLORO-2-NITROBENZOIC ACID;Methyl 5-chloro-2-nitrobenzoate,99%;5-chloro-2-nitro-benzoicacimethylester;4-Chloro-2-methoxycarbonylnitrobenzene
- CBNumber
- CB7360211
- Molecular Formula
- C8H6ClNO4
- Formula Weight
- 215.59
- MOL File
- 51282-49-6.mol
Methyl 5-chloro-2-nitrobenzoate Property
- Melting point:
- 48-52 °C (lit.)
- Boiling point:
- 306.2±22.0 °C(Predicted)
- Density
- 1.4530
- refractive index
- 1.6000 (estimate)
- Flash point:
- >230 °F
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Pale Yellow
- CAS DataBase Reference
- 51282-49-6(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 5-chloro-2-nitro-, methyl ester (51282-49-6)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 36-37/39-26
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 579823
- Product name
- Methyl 5-chloro-2-nitrobenzoate
- Purity
- 97%
- Packaging
- 5g
- Price
- $31.2
- Updated
- 2023/01/07
- Product number
- 579823
- Product name
- Methyl 5-chloro-2-nitrobenzoate
- Purity
- 97%
- Packaging
- 25g
- Price
- $151
- Updated
- 2023/01/07
- Product number
- M1996
- Product name
- Methyl 5-Chloro-2-nitrobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $16
- Updated
- 2025/07/31
- Product number
- M1996
- Product name
- Methyl 5-Chloro-2-nitrobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $26
- Updated
- 2025/07/31
- Product number
- M295683
- Product name
- Methyl 5-chloro-2-nitrobenzoate
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
Methyl 5-chloro-2-nitrobenzoate Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystalline powder or chunks
Synthesis
2516-95-2
74-88-4
51282-49-6
This embodiment relates to the synthesis of methyl 2-nitro-5-chlorobenzoate: to a stirred solution of 5-chloro-2-nitrobenzoic acid (9.393 g, 46.60 mmol) in anhydrous DMF (155 mL) at 0 °C was added potassium carbonate (K2CO3, 13.23 g, 95.72 mmol) and iodomethane (MeI, 19.38 g, 8.5 mL. 136.5 mmol), followed by slow warming of the reaction mixture to 40 °C. After 1 h of reaction, the solution was cooled to room temperature and diluted with ethyl acetate (EtOAc, 115 mL). The organic phase was washed sequentially with water (3 x 100 mL) and saturated sodium chloride solution (3 x 100 mL). The combined organic phases were dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure, and the resulting crude product was purified by silica gel column chromatography with 40-60% ethyl acetate/hexane as eluent to afford methyl 2-nitro-5-chlorobenzoate (9.244 g, 42.87 mmol, 92% yield) as a light yellow solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and 13C NMR (100 MHz, CDCl3).
References
[1] Journal of Organic Chemistry, 2007, vol. 72, # 26, p. 9857 - 9865
[2] Patent: WO2008/156656, 2008, A2. Location in patent: Page/Page column 44; 179-180
Methyl 5-chloro-2-nitrobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 5-chloro-2-nitrobenzoate manufacturers
- Product
- Methyl 5-chloro-2-nitrobenzoate 51282-49-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25