5-Chloroindole

Product Name: 5-Chloroindole
CAS No.: 17422-32-1
Chemical Name: 5-Chloroindole
Synonyms: 5-CHLORO-1H-INDOLE;oroindoL;ChloroIndole;5-CHLOROINDOLE;6-Chloroindole99%;5-CHLOROINDOLE99%;5-Chloroindole 98%;5-Chloroindole >5-Chloroindole ,98%;1H-Indole,5-chloro-
CBNumber: CB2126773
Molecular Formula: C8H6ClN
Formula Weight: 151.59
MOL File: 17422-32-1.mol

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5-Chloroindole Property

Melting point:: 69-71 °C (lit.)
Boiling point:: 130 °C / 0.4mmHg
Density: 1.1976 (rough estimate)
refractive index: 1.5437 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in alcohol.
form: Crystalline Powder
pka: 16.09±0.30(Predicted)
color: White to slightly grayish-green
BRN: 2651
InChIKey: MYTGFBZJLDLWQG-UHFFFAOYSA-N
CAS DataBase Reference: 17422-32-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-20/21/22
Safety Statements: 22-24/25-36-26-37/39
RIDADR: 2811
WGK Germany: 3
F: 10
HazardClass: IRRITANT
HS Code: 29339990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C47604
Product name: 5-Chloroindole
Purity: 98%
Packaging: 1g
Price: $44.58
Updated: 2024/03/01

Sigma-Aldrich

Product number: C47604
Product name: 5-Chloroindole
Purity: 98%
Packaging: 5g
Price: $80.4
Updated: 2024/03/01

TCI Chemical

Product number: C1107
Product name: 5-Chloroindole
Purity: >98.0%(GC)
Packaging: 5g
Price: $86
Updated: 2024/03/01

TCI Chemical

Product number: C1107
Product name: 5-Chloroindole
Purity: >98.0%(GC)
Packaging: 25g
Price: $254
Updated: 2024/03/01

TRC

Product number: C367010
Product name: 5-Chloroindole
Packaging: 2.5g
Price: $155
Updated: 2021/12/16

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5-Chloroindole Chemical Properties,Usage,Production

Chemical Properties

White to slightly greyish-green crystalline powder

Uses

5-Chloroindole is a halo-substituted indole used in the preparation of neurologically active compounds such as atypical antipsychotic agents. 5-Chloroindole has been shown to depress serotonin levels in the brainstem and telencephalon.

Uses

5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts. 5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 29, p. 1625, 1992 DOI: 10.1002/jhet.5570290644
The Journal of Organic Chemistry, 44, p. 578, 1979 DOI: 10.1021/jo01318a021

General Description

5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT₃ receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.

Purification Methods

It is distilled at high vacuum and recrystallises from pet ether (b 40-60o) or (b 80-100o) as glistening plates. The picrate has m 147o (146.5-147.5o)(from *C6H6). [Rydon & Tweddle J Chem Soc 3499 1955, Sugasawa J Org Chem 44 578 1979, Beilstein 20/4 V 34.]

5-Chloroindole Preparation Products And Raw materials

Raw materials

5-Chloro-2-nitrotoluene Diethyl oxalate Ferrous sulfate heptahydrate Potassium

Preparation Products

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5-Chloroindole Suppliers

Americas 1 Belgium 1 Canada 5 China 294 Europe 4 France 1 Germany 8 India 30 Japan 3 Poland 1 Slovakia 1 South Korea 1 Switzerland 4 Ukraine 1 United Kingdom 21 United States 63 Global 439

Clearsynth Labs Limited

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View Lastest Price from 5-Chloroindole manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 5-Chloroindole 17422-32-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Chloroindole 17422-32-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Chemwill Asia Co.,Ltd.

Product: 5-Chloroindole in stock Factory 17422-32-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: TOP 3 Factory in China
Supply Ability: Top 3 largest production capacity Factory
Release date: 2019-04-03

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