ChemicalBook > CAS DataBase List > 5-Chloro-1-indanone

5-Chloro-1-indanone

Product Name
5-Chloro-1-indanone
CAS No.
42348-86-7
Chemical Name
5-Chloro-1-indanone
Synonyms
5-Chloro-2,3-dihydro-1H-inden-1-one;Chloro-1-indan;5-Chloro Indanone;5- chlorineindone;5-CHLORO-1-INDANONE;5-CHLOROINDAN-1-ONE;1-Indanone, 5-chloro-;5-Chloro-1-indanone,98%;5-Chloro-1-indanone,99%;5-Chloro-1-indanone >
CBNumber
CB2148511
Molecular Formula
C9H7ClO
Formula Weight
166.6
MOL File
42348-86-7.mol
More
Less

5-Chloro-1-indanone Property

Melting point:
94-98 °C (lit.)
Boiling point:
124-125 °C (3 mmHg)
Density 
1.1466 (rough estimate)
refractive index 
1.6000 (estimate)
Flash point:
124-125°C/3mm
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly)
form 
Solid
color 
Light Beige to Beige
Water Solubility 
insoluble
BRN 
1448000
InChIKey
MEDSHTHCZIOVPU-UHFFFAOYSA-N
CAS DataBase Reference
42348-86-7(CAS DataBase Reference)
NIST Chemistry Reference
5-Chloro-1-indanone(42348-86-7)
EPA Substance Registry System
1H-Inden-1-one, 5-chloro-2,3-dihydro- (42348-86-7)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
433071
Product name
5-Chloro-1-indanone
Purity
99%
Packaging
5g
Price
$62.3
Updated
2024/03/01
TCI Chemical
Product number
C1644
Product name
5-Chloro-1-indanone
Purity
>97.0%(GC)
Packaging
1g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
C1644
Product name
5-Chloro-1-indanone
Purity
>97.0%(GC)
Packaging
5g
Price
$212
Updated
2024/03/01
Alfa Aesar
Product number
A18308
Product name
5-Chloro-1-indanone, 99%
Packaging
1g
Price
$46.65
Updated
2024/03/01
Alfa Aesar
Product number
A18308
Product name
5-Chloro-1-indanone, 99%
Packaging
5g
Price
$180.65
Updated
2024/03/01
More
Less

5-Chloro-1-indanone Chemical Properties,Usage,Production

Chemical Properties

White Crystal

Uses

5-Chloro-1-indanone is the important intermediate of du pont company's new varieties of pesticides indoxacarb (popular name: indoxacarb), is also a kind of important medicine intermediate simultaneously.
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors.

Uses

5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.

Preparation

3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃.
Synthetic method of 5-chloro-1-indanone

General Description

5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.

5-Chloro-1-indanone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Chloro-1-indanone Suppliers

Fuxin Simai Chemical Technology Co., Ltd.
Tel
13841818553
Email
929964679@qq.com
Country
China
ProdList
446
Advantage
58
Suzhou Runsen Pharmaceutical Technology Co., Ltd.
Tel
0512-65885589 18751140360
Fax
0512-65885589
Email
sales@rosen-chemicals.com
Country
China
ProdList
301
Advantage
58
Beijing Yibai Biotechnology Co., Ltd.
Tel
16600087706
Fax
86-010-60404860
Email
shadow@yibaibiotech.com
Country
China
ProdList
39
Advantage
58
Shandong Yukun Chemical Industry Co. LTD
Tel
18660690289
Email
sales@yukunchem.com
Country
China
ProdList
45
Advantage
58
Shenyang Kelaishen Chemical Products Co., Ltd.
Tel
15840211838; 15840211838
Fax
18640376777
Email
15840211838@163.com
Country
China
ProdList
13
Advantage
58
Shanghai Tuolei Chemical Reagents Co., Ltd.
Tel
86-021-50318510
Fax
021-58650104
Country
China
ProdList
69
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3296
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4550
Advantage
62
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Changzhou Book Chemical Co., Ltd.
Tel
13775119556
Fax
0519-68780180
Email
bookchem@126.com
Country
China
ProdList
552
Advantage
62
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ:3470079902
Email
huawenchem@163.com
Country
China
ProdList
3205
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4000
Advantage
55
Suzhou Guide Fine Material Co.Ltd.
Tel
136-16210669 13914021065
Fax
0512-66627360
Email
sales@guide-chemicals.com
Country
China
ProdList
294
Advantage
60
Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.
Tel
022-60116533 13207668525
Fax
022-60979672
Email
saleskc@scipharmacn.com
Country
China
ProdList
850
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Shanghai Litong Chemical Technology Co.,Ltd.
Tel
13598610367 0373-7129549
Fax
0373-8369699
Email
2468833170@qq.com
Country
China
ProdList
932
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6181
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8888
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Tocopharm Co., Ltd.
Tel
+86-021-69895597 13776836200 +86-13776836200
Fax
021-61292409
Email
tocopharm@gmail.com
Country
China
ProdList
187
Advantage
55
Shanghai Arbor Chemical Co., Ltd.
Tel
021-021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
922
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7876
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
2002
Advantage
62
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Shanghai Hong-chuang Pharma Tech Co., Ltd.
Tel
18151128828
Fax
-
Email
hc-sales@foxmail.com
Country
China
ProdList
2494
Advantage
55
More
Less

View Lastest Price from 5-Chloro-1-indanone manufacturers

Zibo Wei Bin Import & Export Trade Co. Ltd.
Product
5-Chloro-1-indanone 42348-86-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100
Release date
2023-12-14
Henan Fengda Chemical Co., Ltd
Product
5-Chloro-1-indanone 42348-86-7
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
Wuhan Boyuan Import & Export Co., LTD
Product
5-Chloro-1-Indanone 42348-86-7
Price
US $50.00-30.00/kg
Min. Order
1kg
Purity
99.50%
Supply Ability
20tons
Release date
2023-03-02

42348-86-7, 5-Chloro-1-indanoneRelated Search:


  • 5-chloro-2,3-dihydroinden-1-one
  • 5-Chloro-1-indanone,98%
  • 1-Indanone, 5-chloro-5- chlorineindon
  • 5 - chlorine indene ketone
  • Chloro-1-indan
  • 5-CHLORO-1-INDANONE
  • 5-CHLOROINDAN-1-INDANONE
  • 5-CHLOROINDAN-1-ONE
  • 1H-Inden-1-one, 5-chloro-2,3-dihydro-
  • 1-Indanone, 5-chloro-
  • 5-Chloro-2,3-dihydro-1H-inden-1-one
  • 5-Chloro-1-indanone,99%
  • 5-Chloro Indanone
  • 5- chlorineindone
  • 5-Chloro-1-indanone &gt
  • 1-Indanone,5-chloro- (7CI)
  • 2,3- dihydro -5- chloroindolone
  • Indoxacarb intermediate
  • 42348-86-7
  • C9H7OCl
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • Carbonyl Compounds
  • C9
  • Building Blocks
  • C9
  • Carbonyl Compounds
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Benzocycles
  • Indane/Indanone and Derivatives
  • Ketones
  • Indanone & Indene
  • 42348-86-7