ChemicalBook > CAS DataBase List > Avermectin B1b

Avermectin B1b

Product Name
Avermectin B1b
CAS No.
65195-56-4
Chemical Name
Avermectin B1b
Synonyms
AbaMectin B1b;C-076B1b;avermectin b1b;Antibiotic C-076B1b;Abamectin B1b (~90%);Dolamectin Impurity 2;Avermectin B1b 100 μg/ml Acetonitrile;Ivermectin Impurity 2(Ivermectin EP Impurity B);5-O-Demethyl-25-de(1-methylpropyl)-25-isopropylAvermectin A1a;Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-
CBNumber
CB1855054
Molecular Formula
C47H70O14
Formula Weight
859.05
MOL File
65195-56-4.mol
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Avermectin B1b Property

Boiling point:
934.6±65.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
solid
pka
12.42±0.70(Predicted)
color 
white
Stability:
Unstable in Solution, Very Hygroscopic
EPA Substance Registry System
Avermectin B1b (65195-56-4)
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Safety

RIDADR 
2588
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H332Harmful if inhaled

H400Very toxic to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17453
Product name
Avermectin B1b
Purity
≥99%
Packaging
500μg
Price
$189
Updated
2024/03/01
Cayman Chemical
Product number
17453
Product name
Avermectin B1b
Purity
≥99%
Packaging
2.5mg
Price
$802
Updated
2024/03/01
TRC
Product number
A107010
Product name
AbamectinB1b(~90%)
Packaging
0.5mg
Price
$150
Updated
2021/12/16
Usbiological
Product number
A4447-01
Product name
Avermectin B1b
Packaging
500ug
Price
$513
Updated
2021/12/16
TRC
Product number
A107010
Product name
AbamectinB1b(~90%)
Packaging
5mg
Price
$1225
Updated
2021/12/16
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Avermectin B1b Chemical Properties,Usage,Production

Uses

Avermectin B1b is the minor component (<20%) of a commercially available anthelmintic used to control parasitic nematodes in livestock. Avermectin B1b contains a isopropyl residue in the 25-position. In vitro and in vivo studies have shown this analogue to be active, but less potent than the B1a analogue

Definition

ChEBI: Avermectin B1b is an avermectin.

brand name

(Merck)Avomec [Veterinary] (Merial); Bovitin [Veterinary] (Merial); Doratect [Veterinary] (Merial); Duomectin [Veterinary] (Merial); Duotin [Veterinary] (Merial); Endecto (Merck); Enzec (Merck); Enzek (Merck); Parafoil (Merck); Vertimil (Zectin (Merck).

Biological Activity

avermectin b1 is a mixture of avermectins containing >80% avermectin b1a and <20% avermectin b1b. b1a and b1b have very similar biological and toxicological properties.

in vitro

the avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium. avermectin b1 is a natural fermentation product of this bacterium.

in vivo

avermectin b1 therapy resulted in significant decreases in mean strongyle egg after treatment. all horses given ivermectin or avermectin b1 had zero strongyle egg counts 14 and 28 d after treatment. the oral administration of avermectin b1 appeared to be highly efficacious against intestinal strongyles and onchocera microfilaria [1].

References

[1] mogg td, pollitt cc, willmore jp, thompson h. efficacy of avermectin b1 given orally against equine intestinal strongyles and onchocera microfilaria. aust vet j. 1990;67(11):399-401.

Avermectin B1b Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Avermectin B1b manufacturers

Career Henan Chemical Co
Product
avermectin B1b 65195-56-4
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
G/KG/TON
Release date
2020-02-13