ChemicalBook > CAS DataBase List > thonzylamine

thonzylamine

Product Name
thonzylamine
CAS No.
91-85-0
Chemical Name
thonzylamine
Synonyms
NCI-C-60708;Brn 0284655;Neohetramine;thonzylamine;Einecs 202-103-8;thonzylamine USP/EP/BP;63-56-9 (Mono-hydrochloride);2-piriMidina;2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine;N-[2-(Dimethylamino)ethyl]-N-(4-methoxybenzyl)pyrimidin-2-amine
CBNumber
CB1886964
Molecular Formula
C16H22N4O
Formula Weight
286.37
MOL File
91-85-0.mol
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thonzylamine Property

Boiling point:
428.74°C (rough estimate)
Density 
1.0426 (rough estimate)
refractive index 
1.5850 (estimate)
storage temp. 
Hygroscopic, Refrigerator, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Oil
pka
pKa 2.17 (Uncertain);8.96 (Uncertain)
color 
Light Brown to Brown
Water Solubility 
5.441g/L(37.5 ºC)
Stability:
Hygroscopic
CAS DataBase Reference
91-85-0
EPA Substance Registry System
Thonzylamine (91-85-0)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0012617
Product name
THONZYLAMINE
Purity
95.00%
Packaging
1G
Price
$840
Updated
2021/12/16
Chemenu
Product number
CM166801
Product name
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
Purity
95%
Packaging
1g
Price
$729
Updated
2021/12/16
Crysdot
Product number
CD11015812
Product name
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
Purity
95+%
Packaging
1g
Price
$772
Updated
2021/12/16
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thonzylamine Chemical Properties,Usage,Production

Uses

Thonzylamine is a selective H1-histamine receptor anatagonists. Tropine esterase inhibitor.

Definition

ChEBI: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine is a member of methoxybenzenes.

General Description

An oily liquid. Used (in the form of the hydrochloride) as an antihistaminic.

Reactivity Profile

thonzylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products.

Synthesis

Thonzylamine is synthesized by treating the sodium salt of 2-(4-methoxybenzyl)aminopyrimidine with N,N-dimethyl-2-chloroethylamine .

thonzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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thonzylamine Suppliers

Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
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58
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7876
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55
Chengdu Kamel Pharmaceutical Co., Ltd
Tel
028-67136579 15828051124
Email
sales@kamelpharm.com
Country
China
ProdList
1778
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55
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
9038
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
4981
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55
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16028
Advantage
58
Nanjing Xinmeihe Pharmaceutical Co., Ltd.
Tel
025-57672321 13739186949
Fax
025-57672123
Email
2548785915@qq.com
Country
China
ProdList
230
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Hefei TNJ Chemical Industry Co.,Ltd.
Tel
0551-65418671
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34572
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58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
9126
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-87569265 +86-18612256290
Fax
029-88380327
Email
1056@dideu.com
Country
China
ProdList
3131
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58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
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58
Shanghai Luofa Biochemical Technology Co., Ltd.
Tel
021-51111890 15317326293
Email
sales@molnova.com
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China
ProdList
4196
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58
Henan Weitesi Chemical Technology Co. LTD
Tel
0371-0371-55135753 18003832934
Fax
QQ:2853979818
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2853979818@qq.com
Country
China
ProdList
9987
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cjbscvictory
Tel
13348960310 13348960310
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3003867561@qq.com
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China
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9946
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Hubei Baidu Chemical Co., Ltd
Tel
027-59106051 13627137652
Fax
027-59223020
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1438180055@qq.com
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China
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9993
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Hubei xingongli Chemical Co., Ltd
Tel
027-59106151 15172325309
Fax
027-59503710
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1400858877@qq.com
Country
China
ProdList
9965
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840
Email
psaitong@jm-bio.com
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China
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29778
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58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
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product02@bidepharm.com
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China
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63720
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
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1027@dideu.com
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China
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9945
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24018
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Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
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China
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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+86-18521732826
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market@aladdin-e.com
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China
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48467
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Hangzhou FandaChem Co.,Ltd.
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008657128800458; +8615858145714
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LEAPCHEM CO., LTD.
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Hebei Duling International Trade Co. LTD
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+8617333973358
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Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
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info@zzsrm.com
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CHINA
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View Lastest Price from thonzylamine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Thonzylamine 91-85-0
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-08

91-85-0, thonzylamineRelated Search:


  • thonzylamine
  • N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
  • N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine
  • N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyrimidinyl)-1,2-ethanediamine
  • N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-(2-pyrimidinyl)-1,2-ethanediamine
  • N-[2-(Dimethylamino)ethyl]-N-(4-methoxybenzyl)pyrimidin-2-amine
  • NCI-C-60708
  • Neohetramine
  • 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyrimidinyl-
  • 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine
  • 63-56-9 (Mono-hydrochloride)
  • Brn 0284655
  • Einecs 202-103-8
  • Ethylenediamine, N-(p-methoxybenzyl)-N',N'-dimethyl-N-2-pyrimidinyl-
  • N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2-pyrimidyl)ethylenediamine
  • 2-<p.Metossibenzil-(2-diMetilaMinoetil)aMino>piriMidina
  • thonzylamine USP/EP/BP
  • nasal,inhibit,histamine,hypersensitivity,antihistaminic,Thonzylamine,allergic,conjunctivitis,Histamine Receptor,antianaphylactic,congestion,Inhibitor
  • 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyrimidinyl-
  • 91-85-0