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thonzylamine

Product Name
thonzylamine
CAS No.
91-85-0
Chemical Name
thonzylamine
Synonyms
NCI-C-60708;Brn 0284655;Neohetramine;thonzylamine;Einecs 202-103-8;thonzylamine USP/EP/BP;63-56-9 (Mono-hydrochloride);2-piriMidina;2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine;N-[2-(Dimethylamino)ethyl]-N-(4-methoxybenzyl)pyrimidin-2-amine
CBNumber
CB1886964
Molecular Formula
C16H22N4O
Formula Weight
286.37
MOL File
91-85-0.mol
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thonzylamine Property

Boiling point:
428.74°C (rough estimate)
Density 
1.0426 (rough estimate)
refractive index 
1.5850 (estimate)
storage temp. 
Hygroscopic, Refrigerator, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Oil
pka
pKa 2.17 (Uncertain);8.96 (Uncertain)
color 
Light Brown to Brown
Water Solubility 
5.441g/L(37.5 ºC)
Stability:
Hygroscopic
CAS DataBase Reference
91-85-0
EPA Substance Registry System
Thonzylamine (91-85-0)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0012617
Product name
THONZYLAMINE
Purity
95.00%
Packaging
1G
Price
$840
Updated
2021/12/16
Chemenu
Product number
CM166801
Product name
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
Purity
95%
Packaging
1g
Price
$729
Updated
2021/12/16
Crysdot
Product number
CD11015812
Product name
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
Purity
95+%
Packaging
1g
Price
$772
Updated
2021/12/16
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thonzylamine Chemical Properties,Usage,Production

Uses

Thonzylamine is a selective H1-histamine receptor anatagonists. Tropine esterase inhibitor.

Definition

ChEBI: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine is a member of methoxybenzenes.

General Description

An oily liquid. Used (in the form of the hydrochloride) as an antihistaminic.

Reactivity Profile

thonzylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products.

Synthesis

Thonzylamine is synthesized by treating the sodium salt of 2-(4-methoxybenzyl)aminopyrimidine with N,N-dimethyl-2-chloroethylamine .

thonzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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thonzylamine Suppliers

China 29 India 1 United States 8 Global 38
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View Lastest Price from thonzylamine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Thonzylamine 91-85-0
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-12
Shaanxi Dideu Medichem Co. Ltd
Product
Thonzylamine 91-85-0
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-08

91-85-0, thonzylamineRelated Search:

N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine HEXADECYL[2-([P-METHOXYBENZYL]-2-PYRIMIDINYLAMINO)ETHYL]DIMETHYL-AMMONIUM BROMIDE thonzylamine Hetramine thonzylamine hydrochloride

  • thonzylamine
  • N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
  • N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine
  • N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyrimidinyl)-1,2-ethanediamine
  • N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-(2-pyrimidinyl)-1,2-ethanediamine
  • N-[2-(Dimethylamino)ethyl]-N-(4-methoxybenzyl)pyrimidin-2-amine
  • NCI-C-60708
  • Neohetramine
  • 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyrimidinyl-
  • 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine
  • 63-56-9 (Mono-hydrochloride)
  • Brn 0284655
  • Einecs 202-103-8
  • Ethylenediamine, N-(p-methoxybenzyl)-N',N'-dimethyl-N-2-pyrimidinyl-
  • N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2-pyrimidyl)ethylenediamine
  • 2-<p.Metossibenzil-(2-diMetilaMinoetil)aMino>piriMidina
  • thonzylamine USP/EP/BP
  • nasal,inhibit,histamine,hypersensitivity,antihistaminic,Thonzylamine,allergic,conjunctivitis,Histamine Receptor,antianaphylactic,congestion,Inhibitor
  • 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyrimidinyl-
  • 91-85-0