methyl pyridine-3-acetate
- Product Name
- methyl pyridine-3-acetate
- CAS No.
- 39998-25-9
- Chemical Name
- methyl pyridine-3-acetate
- Synonyms
- Methyl 2-(pyridin-3-yl)acetate;EOS-62049;Einecs 254-739-0;METHYL 3-PYRIDYLACETATE;methyl pyridine-3-acetate;Methyl pyridin-3-ylacetate;Methyl 2-(3-Pyridyl)acetate;3-Pyridineacetic acid methyl ester;3-Pyridinylacetic acid methyl ester;Pyridin-3-yl-acetic acid methyl ester
- CBNumber
- CB1894918
- Molecular Formula
- C8H9NO2
- Formula Weight
- 151.16
- MOL File
- 39998-25-9.mol
methyl pyridine-3-acetate Property
- Boiling point:
- 112 °C(Press: 10 Torr)
- Density
- 1.115±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 4.40±0.11(Predicted)
- Appearance
- Light yellow to yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S363855
- Product name
- METHYL 3-PYRIDYLACETATE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $113
- Updated
- 2025/07/31
- Product number
- S363855
- Product name
- METHYL 3-PYRIDYLACETATE
- Purity
- Aldrich
- Packaging
- 250mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- M219543
- Product name
- Methyl2-(Pyridin-3-yl)acetate
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- X5277
- Product name
- Methylpyridine-3-acetate
- Packaging
- 250mg
- Price
- $82
- Updated
- 2021/12/16
- Product number
- 113966
- Product name
- Methyl pyridin-3-ylacetate
- Purity
- 97%
- Packaging
- 1g
- Price
- $371
- Updated
- 2021/12/16
methyl pyridine-3-acetate Chemical Properties,Usage,Production
Synthesis
67-56-1
6419-36-9
39998-25-9
To synthesize methyl (pyridin-3-yl)acetate, the following procedure was used: in a 1L four-necked flask equipped with a nitrogen introduction tube, thermometer, Dimroth condenser, and a dropping funnel, 25.12 g (0.145 mol) of pyridine-3-acetic acid hydrochloride was added. Subsequently 500mL of anhydrous methanol was added. Stir at room temperature under nitrogen protection until the hydrochloride is completely dissolved. 31.12 g (0.248 mol) of thionyl chloride was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was heated to reflux and the reaction was continued for 2.5 hours. After completion of the reaction, the mixture was cooled to room temperature and methanol was removed by distillation under reduced pressure by rotary evaporator. The residue was neutralized to pH neutral with saturated aqueous sodium bicarbonate. The aqueous phase was extracted with 100 mL of ethyl acetate in three fractions, the organic phases were combined and dried over anhydrous sodium sulfate. After filtration to remove the desiccant, the solvent was removed by distillation under reduced pressure to give 21.29 g (0.141 mol) of methyl (pyridin-3-yl)acetate in 97% yield.
References
[1] Patent: EP2390243, 2011, A1. Location in patent: Page/Page column 26
[2] Tetrahedron Letters, 1993, vol. 34, # 2, p. 331 - 334
methyl pyridine-3-acetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from methyl pyridine-3-acetate manufacturers
- Product
- methyl pyridine-3-acetate 39998-25-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2020-01-02